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Protein
Submitted name:

Hepatopancreas trypsin

Gene
N/A
Organism
Astacus leptodactylus (Turkish narrow-clawed crayfish) (Pontastacus leptodactylus)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi64Calcium 1Combined sources1
Metal bindingi66Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi69Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi71Calcium 1Combined sources1
Metal bindingi74Calcium 1Combined sources1
Metal bindingi156Calcium 2Combined sources1
Metal bindingi170Calcium 2; via carbonyl oxygenCombined sources1
Metal bindingi172Calcium 2; via carbonyl oxygenCombined sources1
Metal bindingi224Calcium 2Combined sources1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation
LigandCalciumCombined sources, Metal-bindingCombined sources

Protein family/group databases

MEROPSiS01.035

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatopancreas trypsinImported
OrganismiAstacus leptodactylus (Turkish narrow-clawed crayfish) (Pontastacus leptodactylus)Imported
Taxonomic identifieri6717 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAstacideaAstacoideaAstacidaeAstacus

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 46Combined sources
Disulfide bondi159 ↔ 174Combined sources
Disulfide bondi185 ↔ 213Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
P009745EBI-8755401,EBI-1032263From Bos taurus.

Protein-protein interaction databases

IntActiQ52V24, 1 interactor
MINTiQ52V24

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2F91X-ray1.20A1-237[»]
4BNRX-ray2.00A/B1-237[»]
SMRiQ52V24
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ52V24

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 237Peptidase S1InterPro annotationAdd BLAST237

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Fragment.

Q52V24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IVGGTDATLG EFPYQLSFQE TFIGFSFHFC GASIYNENYA ITAGHCAYGD
60 70 80 90 100
DYENPSGLQI VAGELDMSVN EGSEQIITVS KIILHENFDY NLLDNDISLL
110 120 130 140 150
KLSGSLTFND NVAPIALPEQ GHTATGDVIV TGWGTTSEGG NTPDVLQKVT
160 170 180 190 200
VPLVSDEDCR ADYGADEILD SMICAGVPEG GKDSCQGDSG GPLAASDTGS
210 220 230
TYLAGIVSWG YGCARPGYPG VYTEVSYHVD WIKANAV
Length:237
Mass (Da):25,033
Last modified:May 24, 2005 - v1
Checksum:iE9C74D1EA3847025
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY906961 mRNA Translation: AAX98287.1

Similar proteinsi

Entry informationi

Entry nameiQ52V24_ASTLP
AccessioniPrimary (citable) accession number: Q52V24
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: February 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

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