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Q52T95

- Q52T95_STAAU

UniProt

Q52T95 - Q52T95_STAAU

Protein
Submitted name:

Enterotoxin type I

Gene
N/A
Organism
Staphylococcus aureus
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 2 (02 May 2006)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi169 – 1691Zinc; via pros nitrogenImported
    Metal bindingi207 – 2071Zinc; via tele nitrogenImported
    Metal bindingi209 – 2091ZincImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. pathogenesis Source: InterPro

    Keywords - Ligandi

    Metal-bindingImported, ZincImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Enterotoxin type IImported
    OrganismiStaphylococcus aureusImported
    Taxonomic identifieri1280 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: InterPro

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2G9HX-ray2.00D1-218[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.10.20.120. 1 hit.
    InterProiIPR008992. Enterotoxin.
    IPR006126. Staph/Strept_toxin_CS.
    IPR006173. Staph_tox_OB.
    IPR016091. SuperAg_toxin_C.
    IPR013307. Superantigen_bac.
    IPR006123. Toxin_b-grasp_Staph/Strep.
    [Graphical view]
    PfamiPF02876. Stap_Strp_tox_C. 1 hit.
    PF01123. Stap_Strp_toxin. 1 hit.
    [Graphical view]
    PRINTSiPR01898. SAGSUPRFAMLY.
    SUPFAMiSSF50203. SSF50203. 1 hit.
    SSF54334. SSF54334. 1 hit.
    PROSITEiPS00278. STAPH_STREP_TOXIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q52T95-1 [UniParc]FASTAAdd to Basket

    « Hide

    QGDIGVGNLR NFYTKHDYID LKGLIDKNLP SANQLEFSTG INDLISESNN    50
    WDEISKFKGK KLDIFGIDYN GPCKSKYMYG GATLSGQYLN SARKIPINLW 100
    VNGKHKTIST DKISTNKKLV TAQEIDVKLR RYLQEEYNIY GHNSTGKGKE 150
    YGYKSKFYSG FNKGKVLFHL NDEKSFSYDL FYTGDGVPVS FLKIYEDNKI 200
    IESEKFHLDV EISYVDSN 218
    Length:218
    Mass (Da):24,927
    Last modified:May 2, 2006 - v2
    Checksum:i72874C10B8717038
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei218 – 2181Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY961381 Genomic DNA. Translation: AAX84810.2.
    AY961387 Genomic DNA. Translation: AAX84816.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY961381 Genomic DNA. Translation: AAX84810.2 .
    AY961387 Genomic DNA. Translation: AAX84816.2 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2G9H X-ray 2.00 D 1-218 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.10.20.120. 1 hit.
    InterProi IPR008992. Enterotoxin.
    IPR006126. Staph/Strept_toxin_CS.
    IPR006173. Staph_tox_OB.
    IPR016091. SuperAg_toxin_C.
    IPR013307. Superantigen_bac.
    IPR006123. Toxin_b-grasp_Staph/Strep.
    [Graphical view ]
    Pfami PF02876. Stap_Strp_tox_C. 1 hit.
    PF01123. Stap_Strp_toxin. 1 hit.
    [Graphical view ]
    PRINTSi PR01898. SAGSUPRFAMLY.
    SUPFAMi SSF50203. SSF50203. 1 hit.
    SSF54334. SSF54334. 1 hit.
    PROSITEi PS00278. STAPH_STREP_TOXIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule."
      Fernandez M.M., Guan R., Swaminathan C.P., Malchiodi E.L., Mariuzza R.A.
      J. Biol. Chem. 281:25356-25364(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH ZINC.
    2. "Binding of natural variants of staphylococcal superantigens SEG and SEI to TCR and MHC class II molecule."
      Fernandez M.M., De Marzi M.C., Berguer P., Burzyn D., Langley R.J., Piazzon I., Mariuzza R.A., Malchiodi E.L.
      Mol. Immunol. 43:927-938(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Fc30Imported and Fc35Imported.

    Entry informationi

    Entry nameiQ52T95_STAAU
    AccessioniPrimary (citable) accession number: Q52T95
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 24, 2005
    Last sequence update: May 2, 2006
    Last modified: October 1, 2014
    This is version 41 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3