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Q52T95

- Q52T95_STAAU

UniProt

Q52T95 - Q52T95_STAAU

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Protein
Submitted name:

Enterotoxin type I

Gene
N/A
Organism
Staphylococcus aureus
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi169 – 1691Zinc; via pros nitrogenImported
Metal bindingi207 – 2071Zinc; via tele nitrogenImported
Metal bindingi209 – 2091ZincImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. pathogenesis Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-bindingImported, ZincImported

Names & Taxonomyi

Protein namesi
Submitted name:
Enterotoxin type IImported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2G9HX-ray2.00D1-218[»]

Family & Domainsi

Family and domain databases

Gene3Di3.10.20.120. 1 hit.
InterProiIPR008992. Enterotoxin.
IPR006126. Staph/Strept_toxin_CS.
IPR006173. Staph_tox_OB.
IPR016091. SuperAg_toxin_C.
IPR013307. Superantigen_bac.
IPR006123. Toxin_b-grasp_Staph/Strep.
[Graphical view]
PfamiPF02876. Stap_Strp_tox_C. 1 hit.
PF01123. Stap_Strp_toxin. 1 hit.
[Graphical view]
PRINTSiPR01898. SAGSUPRFAMLY.
SUPFAMiSSF50203. SSF50203. 1 hit.
SSF54334. SSF54334. 1 hit.
PROSITEiPS00278. STAPH_STREP_TOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q52T95-1 [UniParc]FASTAAdd to Basket

« Hide

QGDIGVGNLR NFYTKHDYID LKGLIDKNLP SANQLEFSTG INDLISESNN    50
WDEISKFKGK KLDIFGIDYN GPCKSKYMYG GATLSGQYLN SARKIPINLW 100
VNGKHKTIST DKISTNKKLV TAQEIDVKLR RYLQEEYNIY GHNSTGKGKE 150
YGYKSKFYSG FNKGKVLFHL NDEKSFSYDL FYTGDGVPVS FLKIYEDNKI 200
IESEKFHLDV EISYVDSN 218
Length:218
Mass (Da):24,927
Last modified:May 2, 2006 - v2
Checksum:i72874C10B8717038
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei218 – 2181Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY961381 Genomic DNA. Translation: AAX84810.2.
AY961387 Genomic DNA. Translation: AAX84816.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY961381 Genomic DNA. Translation: AAX84810.2 .
AY961387 Genomic DNA. Translation: AAX84816.2 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2G9H X-ray 2.00 D 1-218 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.10.20.120. 1 hit.
InterProi IPR008992. Enterotoxin.
IPR006126. Staph/Strept_toxin_CS.
IPR006173. Staph_tox_OB.
IPR016091. SuperAg_toxin_C.
IPR013307. Superantigen_bac.
IPR006123. Toxin_b-grasp_Staph/Strep.
[Graphical view ]
Pfami PF02876. Stap_Strp_tox_C. 1 hit.
PF01123. Stap_Strp_toxin. 1 hit.
[Graphical view ]
PRINTSi PR01898. SAGSUPRFAMLY.
SUPFAMi SSF50203. SSF50203. 1 hit.
SSF54334. SSF54334. 1 hit.
PROSITEi PS00278. STAPH_STREP_TOXIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule."
    Fernandez M.M., Guan R., Swaminathan C.P., Malchiodi E.L., Mariuzza R.A.
    J. Biol. Chem. 281:25356-25364(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH ZINC.
  2. "Binding of natural variants of staphylococcal superantigens SEG and SEI to TCR and MHC class II molecule."
    Fernandez M.M., De Marzi M.C., Berguer P., Burzyn D., Langley R.J., Piazzon I., Mariuzza R.A., Malchiodi E.L.
    Mol. Immunol. 43:927-938(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Fc30Imported and Fc35Imported.

Entry informationi

Entry nameiQ52T95_STAAU
AccessioniPrimary (citable) accession number: Q52T95
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 2, 2006
Last modified: September 3, 2014
This is version 40 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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