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Protein
Submitted name:

Enterotoxin type I

Gene
N/A
Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi169 – 1691Zinc; via pros nitrogenCombined sources
Metal bindingi207 – 2071Zinc; via tele nitrogenCombined sources
Metal bindingi209 – 2091ZincCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Enterotoxin type IImported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2G9HX-ray2.00D1-218[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di3.10.20.120. 1 hit.
InterProiIPR008992. Enterotoxin.
IPR006126. Staph/Strept_toxin_CS.
IPR006173. Staph_tox_OB.
IPR016091. SuperAg_toxin_C.
IPR013307. Superantigen_bac.
IPR006123. Toxin_b-grasp_Staph/Strep.
[Graphical view]
PfamiPF02876. Stap_Strp_tox_C. 1 hit.
PF01123. Stap_Strp_toxin. 1 hit.
[Graphical view]
PRINTSiPR01898. SAGSUPRFAMLY.
SUPFAMiSSF50203. SSF50203. 1 hit.
SSF54334. SSF54334. 1 hit.
PROSITEiPS00278. STAPH_STREP_TOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q52T95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QGDIGVGNLR NFYTKHDYID LKGLIDKNLP SANQLEFSTG INDLISESNN
60 70 80 90 100
WDEISKFKGK KLDIFGIDYN GPCKSKYMYG GATLSGQYLN SARKIPINLW
110 120 130 140 150
VNGKHKTIST DKISTNKKLV TAQEIDVKLR RYLQEEYNIY GHNSTGKGKE
160 170 180 190 200
YGYKSKFYSG FNKGKVLFHL NDEKSFSYDL FYTGDGVPVS FLKIYEDNKI
210
IESEKFHLDV EISYVDSN
Length:218
Mass (Da):24,927
Last modified:May 2, 2006 - v2
Checksum:i72874C10B8717038
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei218 – 2181Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY961381 Genomic DNA. Translation: AAX84810.2.
AY961387 Genomic DNA. Translation: AAX84816.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY961381 Genomic DNA. Translation: AAX84810.2.
AY961387 Genomic DNA. Translation: AAX84816.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2G9HX-ray2.00D1-218[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.10.20.120. 1 hit.
InterProiIPR008992. Enterotoxin.
IPR006126. Staph/Strept_toxin_CS.
IPR006173. Staph_tox_OB.
IPR016091. SuperAg_toxin_C.
IPR013307. Superantigen_bac.
IPR006123. Toxin_b-grasp_Staph/Strep.
[Graphical view]
PfamiPF02876. Stap_Strp_tox_C. 1 hit.
PF01123. Stap_Strp_toxin. 1 hit.
[Graphical view]
PRINTSiPR01898. SAGSUPRFAMLY.
SUPFAMiSSF50203. SSF50203. 1 hit.
SSF54334. SSF54334. 1 hit.
PROSITEiPS00278. STAPH_STREP_TOXIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule."
    Fernandez M.M., Guan R., Swaminathan C.P., Malchiodi E.L., Mariuzza R.A.
    J. Biol. Chem. 281:25356-25364(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH ZINC.
  2. "Binding of natural variants of staphylococcal superantigens SEG and SEI to TCR and MHC class II molecule."
    Fernandez M.M., De Marzi M.C., Berguer P., Burzyn D., Langley R.J., Piazzon I., Mariuzza R.A., Malchiodi E.L.
    Mol. Immunol. 43:927-938(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Fc30Imported and Fc35Imported.

Entry informationi

Entry nameiQ52T95_STAAU
AccessioniPrimary (citable) accession number: Q52T95
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 2, 2006
Last modified: January 7, 2015
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.