Q52R86 (Q52R86_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Janus kinase EMBL AAY16348.1

Submitted name:
Janus kinase 2 EMBL ABK91947.1

Gene names

Name:

JAK2 EMBL AAY16348.1

Organism

Homo sapiens (Human) EMBL AAY16348.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	29 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Kinase EMBL AAY16348.1 Transferase
Gene Ontology (GO)
Molecular function	kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAY16348.1
	Non-terminal residue	29	1	EMBL AAY16348.1

Sequences

	Sequence		Length	Mass (Da)
	Q52R86 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 82C6C73015A51975	FASTA	29	3,252
	10 20 SFFEAASMMS KLSHKHLVLN YGVCFCGDE

References

[1]	"A gain of function mutation of Jak2 in myeloproliferative disorders." Kralovics R., Passamonti F., Buser A.S., Teo S.-S., Tiedt R., Passweg J.R., Cazzola M., Skoda R.C. N. Engl. J. Med. 0:0-0(2005) Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Frequencies of JAK2 (Janus kinase 2 protein gene) V617F G->T mutation detected in patients with 'Polycythemia Vera'." Kutlar F., Li T., Davis D.H., Jillella A., Natarajan K., McDonough C., Dainer P., Nechtman J., Kutlar A. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"A novel JAK2 mutation." Wong C.L.P., Ma E.S.K., Wang C.L.N., Lam H.Y., Ma S.Y. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY973037 Genomic DNA. Translation: AAY16348.1. EF094945 Genomic DNA. Translation: ABK91947.1. EF194100 Genomic DNA. Translation: ABM69254.1.
IPI	IPI00973392.
UniGene	Hs.656213.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q52R86.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q52R86.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

Q52R86_HUMAN

Accession

Primary (citable) accession number: Q52R86

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	November 16, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.