Q52QJ1 (Q52QJ1_PRODI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Thiazoline oxidase/subtilisin-like protease EMBL AAY21156.1

Gene names

Name:

patG EMBL AAY21156.1

Organism

Prochloron didemni EMBL AAY21156.1

Taxonomic identifier

1216 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Prochlorales › Prochloraceae › Prochloron

Protein attributes

Sequence length	1191 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Hydrolase Protease EMBL AAY21156.1
Technical term	3D-structure PDB 4AKS PDB 4AKT PDB 4H6X
Gene Ontology (GO)
Biological_process	oxidation-reduction process Inferred from electronic annotation. Source: GOC proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	oxidoreductase activity Inferred from electronic annotation. Source: InterPro serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q52QJ1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: BE9075F6BBCF3CCC	FASTA	1,191	130,557
	10 20 30 40 50 60 MFSIMITIDY PFTVSLNRDI QVTSTEDYYT LQVTESDPSA WLTFATTPAM DMAFDHLKAG 70 80 90 100 110 120 TTTESLVQTL AELGGPAARE QFALTLQQLD ERGWLSYAVL PLAEAIPMVE SAELNLPGNP 130 140 150 160 170 180 HWMETGVTLS RFAYQHPYEG TMVLESPLSK FRVKLLDWRA SALLAQLAQP QTLGTIAPPP 190 200 210 220 230 240 YLGPETAYQF LNLLWATGFL ASDHEPVSLQ LWDFHNLLFH SRSRLGRHDY PGTDLNVDNW 250 260 270 280 290 300 SDFPVVKPPM SDRIVPLPRP NLEALMSNDA TLTEAIETRK SVREYDDDNP ITIEQLGELL 310 320 330 340 350 360 YRAARVTKLL SPEERFGKLW QQNKPVFEEA GVDEGEFSHR PYPGGGAMYE LEIYPVVRLC 370 380 390 400 410 420 QGLSQGVYHY DPLNHQLEQI VESKDDIFAV SGSPLASKLG PHVLLVITAR FGRLFRLYRS 430 440 450 460 470 480 VAYALVLKHV GVLQQNLYLV ATNMGLAPCA GGAGDSDAFA QVTGIDYVEE SAVGEFILGS 490 500 510 520 530 540 LASEVESDVV EGEDEIESAG VSASEVESSA TKQKVALHPH DLDERIPGLA DLHNQTLGDP 550 560 570 580 590 600 QITIVIIDGD PDYTLSCFEG AEVSKVFPYW HEPAEPITPE DYAAFQSIRD QGLKGKEKEE 610 620 630 640 650 660 ALEAVIPDTK DRIVLNDHAC HVTSTIVGQE HSPVFGIAPN CRVINMPQDA VIRGNYDDVM 670 680 690 700 710 720 SPLNLARAID LALELGANII HCAFCRPTQT SEGEEILVQA IKKCQDNNVL IVSPTGNNSN 730 740 750 760 770 780 ESWCLPAVLP GTLAVGAAKV DGTPCHFSNW GGNNTKEGIL APGEEILGAQ PCTEEPVRLT 790 800 810 820 830 840 GTSMAAPVMT GISALLMSLQ VQQGKPVDAE AVRTALLKTA IPCDPEVVEE PERCLRGFVN 850 860 870 880 890 900 IPGAMKVLFG QPSVTVSFAG GQATRTEHPG YATVAPASIP EPMAERATPA VQAATATEMV 910 920 930 940 950 960 IAPSTEPANP ATVEASTAFS GNVYALGTIG YDFGDEARRD TFKERMADPY DARQMVDYLD 970 980 990 1000 1010 1020 RNPDEARSLI WTLNLEGDVI YALDPKGPFA TNVYEIFLQM LAGQLEPETS ADFIERLSVP 1030 1040 1050 1060 1070 1080 ARRTTRTVEL FSGEVMPVVN VRDPRGMYGW NVNALVDAAL ATVEYEEADE DSLRQGLTAF 1090 1100 1110 1120 1130 1140 LNRVYHDLHN LGQTSRDRAL NFTVTNTFQA ASTFAQAIAS GRQLDTIEVN KSPYCRLNSD 1150 1160 1170 1180 1190 CWDVLLTFYD PEHGRRSRRV FRFTLDVVYV LPVTVGSIKS WSLPGKGTVS K

References

[1]	"Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella." Schmidt E.W., Nelson J.T., Rasko D.A., Sudek S., Eisen J.A., Haygood M.G., Ravel J. Proc. Natl. Acad. Sci. U.S.A. 102:7315-7320(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Reef EMBL AAY21156.1.
[2]	"Structures of cyanobactin maturation enzymes define a family of transamidating proteases." Agarwal V., Pierce E., McIntosh J., Schmidt E.W., Nair S.K. Chem. Biol. 19:1411-1422(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 513-866.
[3]	"The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain." Koehnke J., Bent A., Houssen W.E., Zollman D., Morawitz F., Shirran S., Vendome J., Nneoyiegbe A.F., Trembleau L., Botting C.H., Smith M.C., Jaspars M., Naismith J.H. Nat. Struct. Mol. Biol. 19:767-772(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.19 ANGSTROMS) OF 492-851.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY986476 Genomic DNA. Translation: AAY21156.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4AKS	X-ray	2.19	A/B	492-851	[»]
4AKT	X-ray	2.63	A/B	492-851	[»]
4H6X	X-ray	2.00	A/B	513-866	[»]

ProteinModelPortal

Q52QJ1.

ModBase

Search...

Protein family/group databases

MEROPS

S08.146.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

3.40.109.10. 2 hits.
3.40.50.200. 2 hits.

InterPro

IPR000415. Nitroreductase-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR023830. Peptidase_S8A_PatG.
IPR020051. SagB-type_dehydrogenase.
[Graphical view]

PANTHER

PTHR10795. PTHR10795. 1 hit.

Pfam

PF00881. Nitroreductase. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]

SUPFAM

SSF55469. Nitroreductase. 1 hit.
SSF52743. Pept_S8_S53. 1 hit.

TIGRFAMs

TIGR03605. antibiot_sagB. 1 hit.
TIGR03895. protease_PatA. 1 hit.

PROSITE

PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q52QJ1_PRODI

Accession

Primary (citable) accession number: Q52QJ1

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)