ID   Q52NH2_BACAN            Unreviewed;       800 AA.
AC   Q52NH2;
DT   24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT   24-MAY-2005, sequence version 1.
DT   21-SEP-2011, entry version 17.
DE   SubName: Full=Edema factor;
GN   Name=cya;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=A16R;
RA   Xu J., Dong D., Chen W.;
RT   "Edema factor gene of Bacillus anthracis strain A16R.";
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AY997301; AAY15238.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q52NH2; -.
DR   SMR; Q52NH2; 64-798.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0008294; F:calcium- and calmodulin-responsive adenylate cyclase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0009405; P:pathogenesis; IEA:InterPro.
DR   InterPro; IPR005165; Anthrax_toxin_edema_cen.
DR   InterPro; IPR003541; Anthrax_toxin_lethal/edema.
DR   InterPro; IPR014781; Anthrax_toxin_lethal/edema_N/C.
DR   InterPro; IPR024079; MetalloPept_cat_dom.
DR   Gene3D; G3DSA:3.40.390.10; G3DSA:3.40.390.10; 1.
DR   Pfam; PF03497; Anthrax_toxA; 1.
DR   Pfam; PF07737; ATLF; 1.
DR   PRINTS; PR01392; ANTHRAXTOXNA.
PE   4: Predicted;
SQ   SEQUENCE   800 AA;  92462 MW;  D739CCE23950EDC8 CRC64;
     MTRNKFIPNK FSIISFSVLL FAISSSQAIE VNAMNEHYTE SDIKRNHKTE KNKTEKEKFK
     DSINNLVKTE FTNETLDKIQ QTQGLLKKIP KDVLEIYSEL GGEIYFTDID LVEHKELQDL
     SEEEKNSMNS RGEKVPFASR FVFEKKRETP KLIINIKDYA INSEQSKEVY YEIGKGISLD
     IISKDKSLDP EFLNLIKSLS DDSDSSDLLF SQKFKEKLEL NNKSIDINFI KENLTEFQHA
     FSLAFSYYFA PDHRTVLELY APDMFEYMNK LEKGGFEKIS ESLKKEGVEK DRIDVLKGEK
     ALKASGLVPE HADAFKKIAR ELNTYILFRP VNKLATNLIK SGVATKGLNV HVKSSDWGPV
     AGYIPFDQDL SKKHGQQLAV EKGNLENKKS ITEHEGEIGK IPLKLDHLRI EELKENGIIL
     KGKKEIDNGK KYYLLESNNQ VYEFRISDEN NEVQYKTKEG KITVLGEKFN WRNIEVMAKN
     VEGVLKPLTA DYDLFALAPS LTEIKKQIPQ KEWDKVVNTP NSLEKQKGVT NLLIKYGIER
     KPDSTKGTLS NWQKQMLDRL NEAVKYTGYT GGDVVNHGTE QDNEEFPEKD NEIFIINPEG
     EFILTKNWEM TGRFIEKNIT GKDYLYYFNR SYNKIAPGNK AYIEWTDPIT KAKINTIPTS
     AEFIKNLSSI RRSSNVGVYK DSGDKDEFAK KESVKKIAGY LSDYYNSANH IFSQEKKRKI
     SIFRGIQAYN EIENVLKSKQ IAPEYKNYFQ YLKERITNQV QLLLTHQKSN IEFKLLYKQL
     NFTENETDNF EVFQKIIDEK
//