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Q52LC2 (VAS1L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
V-type proton ATPase subunit S1-like protein
Alternative name(s):
Vacuolar proton pump subunit S1-like protein
Gene names
Name:ATP6AP1L
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the vacuolar ATPase subunit S1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 224224V-type proton ATPase subunit S1-like protein
PRO_0000342377

Regions

Transmembrane147 – 16721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q52LC2 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 65C104B815443678

FASTA22425,310
        10         20         30         40         50         60 
MRLWKARVLK LVLKTAKDSR LGLNSKWLSL KLGDAGNPRS LAIRFILTNY NKLSIQSWFS 

        70         80         90        100        110        120 
LRRVEIISNN SIQAVFNPTG VYAPSGYSYR CQRVGSLQQD QALLLPSDTD DGSSLWEVTF 

       130        140        150        160        170        180 
IDFQIQGFAI KGGRFTKAQD CASSFSPAFL IGLAMSLILL LVLAYALHML IYLRYLDQQY 

       190        200        210        220 
DLIASPAHFS QLKARDTAEE KELLRSQGAE CYKLRSQQIS KIYV 

« Hide

References

[1]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH471084 Genomic DNA. Translation: EAW95889.1.
BC093982 mRNA. Translation: AAH93982.1.
BC112191 mRNA. Translation: AAI12192.1.
RefSeqNP_001017971.1. NM_001017971.1.
UniGeneHs.729805.

3D structure databases

ProteinModelPortalQ52LC2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000369513.

PTM databases

PhosphoSiteQ52LC2.

Polymorphism databases

DMDM74735800.

Proteomic databases

PaxDbQ52LC2.
PRIDEQ52LC2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000380167; ENSP00000369513; ENSG00000205464.
ENST00000439350; ENSP00000391381; ENSG00000205464.
GeneID92270.
KEGGhsa:92270.
UCSCuc003khv.3. human.

Organism-specific databases

CTD92270.
GeneCardsGC05P081612.
HGNCHGNC:28091. ATP6AP1L.
HPAHPA053771.
neXtProtNX_Q52LC2.
PharmGKBPA164716384.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG248409.
HOGENOMHOG000154807.
InParanoidQ52LC2.
OMAQIQGFAI.
OrthoDBEOG75TMBV.
PhylomeDBQ52LC2.
TreeFamTF325819.

Gene expression databases

BgeeQ52LC2.
GenevestigatorQ52LC2.

Family and domain databases

InterProIPR008388. ATPase_V1-cplx_s1su.
[Graphical view]
PANTHERPTHR12471. PTHR12471. 1 hit.
ProtoNetSearch...

Other

GenomeRNAi92270.
NextBio77659.
PROQ52LC2.

Entry information

Entry nameVAS1L_HUMAN
AccessionPrimary (citable) accession number: Q52LC2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 5

Human chromosome 5: entries, gene names and cross-references to MIM