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Protein

Importin subunit alpha

Gene

Kpna2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Functions in nuclear protein import.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Importin subunit alphaUniRule annotation
Gene namesi
Name:Kpna2Imported
ORF Names:mCG_2886Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:103561. Kpna2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000018362.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137310.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6060IBBInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the importin alpha family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0166. Eukaryota.
COG5064. LUCA.
GeneTreeiENSGT00760000119094.
HOVERGENiHBG001846.
KOiK15043.
OMAiIVPICIR.
OrthoDBiEOG091G095Z.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR032413. Arm_3.
IPR000225. Armadillo.
IPR002652. Importin-a_IBB.
IPR024931. Importing_su_alpha.
[Graphical view]
PfamiPF00514. Arm. 8 hits.
PF16186. Arm_3. 1 hit.
PF01749. IBB. 1 hit.
[Graphical view]
PIRSFiPIRSF005673. Importin_alpha. 1 hit.
SMARTiSM00185. ARM. 8 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 6 hits.
PS51214. IBB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q52L97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTNENANLP AARLNRFKNK GKDSTEMRRR RIEVNVELRK AKKDEQMLKR
60 70 80 90 100
RNVSSFPDDA TSPLQENRNN QGTVNWSVED IVKGINSNNL ESQLQATQAA
110 120 130 140 150
RKLLSREKQP PIDNIIRAGL IPKFVSFLGK TDCSPIQFES AWALTNIASG
160 170 180 190 200
TSEQTKAVVD GGAIPAFISL LASPHAHISE QAVWALGNIA GDGSAFRDLV
210 220 230 240 250
IKHGAIDPLL ALLAVPDLST LACGYLRNLT WTLSNLCRNK NPAPPLDAVE
260 270 280 290 300
QILPTLVRLL HHNDPEVLAD SCWAISYLTD GPNERIEMVV KKGVVPQLVK
310 320 330 340 350
LLGATELPIV TPALRAIGNI VTGTDEQTQK VIDAGALAVF PSLLTNPKTN
360 370 380 390 400
IQKEATWTMS NITAGRQDQI QQVVNHGLVP FLVGVLSKAD FKTQKEAAWA
410 420 430 440 450
ITNYTSGGTV EQIVYLVHCG IIEPLMNLLS AKDTKIIQVI LDAISNIFQA
460 470 480 490 500
AEKLGETEKL SIMIEECGGL DKIEALQRHE NESVYKASLN LIEKYFSVEE
510 520
EEDQNVVPET TSEGFAFQVQ DGAPGTFNF
Length:529
Mass (Da):57,928
Last modified:May 24, 2005 - v1
Checksum:i19E64AA3E9C3C7B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC094011 mRNA. Translation: AAH94011.1.
AK139850 mRNA. Translation: BAE24160.1.
AK147135 mRNA. Translation: BAE27705.1.
AK165577 mRNA. Translation: BAE38268.1.
AK166577 mRNA. Translation: BAE38866.1.
AK166790 mRNA. Translation: BAE39020.1.
AK166982 mRNA. Translation: BAE39164.1.
AK167551 mRNA. Translation: BAE39616.1.
AK169283 mRNA. Translation: BAE41041.1.
CH466558 Genomic DNA. Translation: EDL34317.1.
CH466558 Genomic DNA. Translation: EDL34318.1.
CH466558 Genomic DNA. Translation: EDL34319.1.
RefSeqiNP_034785.1. NM_010655.3.
UniGeneiMm.12508.
Mm.391577.
Mm.423000.

Genome annotation databases

GeneIDi16647.
KEGGimmu:16647.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC094011 mRNA. Translation: AAH94011.1.
AK139850 mRNA. Translation: BAE24160.1.
AK147135 mRNA. Translation: BAE27705.1.
AK165577 mRNA. Translation: BAE38268.1.
AK166577 mRNA. Translation: BAE38866.1.
AK166790 mRNA. Translation: BAE39020.1.
AK166982 mRNA. Translation: BAE39164.1.
AK167551 mRNA. Translation: BAE39616.1.
AK169283 mRNA. Translation: BAE41041.1.
CH466558 Genomic DNA. Translation: EDL34317.1.
CH466558 Genomic DNA. Translation: EDL34318.1.
CH466558 Genomic DNA. Translation: EDL34319.1.
RefSeqiNP_034785.1. NM_010655.3.
UniGeneiMm.12508.
Mm.391577.
Mm.423000.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137310.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi16647.
KEGGimmu:16647.

Organism-specific databases

CTDi3838.
MGIiMGI:103561. Kpna2.

Phylogenomic databases

eggNOGiKOG0166. Eukaryota.
COG5064. LUCA.
GeneTreeiENSGT00760000119094.
HOVERGENiHBG001846.
KOiK15043.
OMAiIVPICIR.
OrthoDBiEOG091G095Z.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018362.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR032413. Arm_3.
IPR000225. Armadillo.
IPR002652. Importin-a_IBB.
IPR024931. Importing_su_alpha.
[Graphical view]
PfamiPF00514. Arm. 8 hits.
PF16186. Arm_3. 1 hit.
PF01749. IBB. 1 hit.
[Graphical view]
PIRSFiPIRSF005673. Importin_alpha. 1 hit.
SMARTiSM00185. ARM. 8 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 6 hits.
PS51214. IBB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ52L97_MOUSE
AccessioniPrimary (citable) accession number: Q52L97
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.