Q52KF7 (Q52KF7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Discs, large homolog 3 (Drosophila) EMBL CAM15070.1

Submitted name:
Dlgh3 protein EMBL AAH94368.1
Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000000901

Gene names

Name:	Dlg3 Ensembl ENSMUSP00000000901 MGI 1888986
Synonyms:	Dlgh3 MGI 1888986 EMBL AAH94368.1
ORF Names:	RP23-142M12.1-006 EMBL CAM15070.1

Organism

Mus musculus (Mouse) EMBL AAH94368.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	817 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. SAAS SAAS008145 RuleBase RU003338 Contains 3 PDZ (DHR) domains. RuleBase RU003354

Ontologies

Keywords
Domain	SH3 domain SAAS SAAS008145 RuleBase RU003338
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q52KF7 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: F969768FA0D82350	FASTA	817	90,328
	10 20 30 40 50 60 MHKHQHCCKC PECYEVTRLA ALRRLEPPGY GDWQVPDPYG PSGGNGASSG YGGYSSQTLP 70 80 90 100 110 120 SQAGATPTPR TKAKLIPTGR DVGPVPPKPV PGKSTPKLNG SGPGWWPECT CTNRDWYEQV 130 140 150 160 170 180 NGSDGMFKYE EIVLERGNSG LGFSIAGGID NPHVPDDPGI FITKIIPGGA AAMDGRLGVN 190 200 210 220 230 240 DCVLRVNEVD VSEVVHSRAV EALKEAGPVV RLVVRRRQPP PETIMEVNLL KGPKGLGFSI 250 260 270 280 290 300 AGGIGNQHIP GDNSIYITKI IEGGAAQKDG RLQIGDRLLA VNNTNLQDVR HEEAVASLKN 310 320 330 340 350 360 TSDMVYLKVA KPGSIHLNDM YAPPDYASTF TALADNHISH NSSLGYLGAV ESKVTYPAPP 370 380 390 400 410 420 QVPPTRYSPI PRHMLAEEDF TREPRKIILH KGSTGLGFNI VGGEDGEGIF VSFILAGGPA 430 440 450 460 470 480 DLSGELRRGD RILSVNGVNL RNATHEQAAA ALKRAGQSVT IVAQYRPEEY SRFESKIHDL 490 500 510 520 530 540 REQMMNSSMS SGSGSLRTSE KRSLYVRALF DYDRTRDSCL PSQGLSFSYG DILHVINASD 550 560 570 580 590 600 DEWWQARLVT PHGESEQIGV IPSKKRVEKK ERARLKTVKF HARTGMIESN RDFPGLSDDY 610 620 630 640 650 660 YGAKNLKGQE DAILSYEPVT RQEIHYARPV IILGPMKDRV NDDLISEFPH KFGSCVPHTT 670 680 690 700 710 720 RPRRDNEVDG QDYHFVVSRE QMEKDIQDNK FIEAGQFNDN LYGTSIQSVR AVAERGKHCI 730 740 750 760 770 780 LDVSGNAIKR LQQAQLYPIA IFIKPKSIEA LMEMNRRQTY EQANKIFDKA MKLEQEFGEY 790 800 810 FTAIVQGDSL EEIYNKIKQI IEDQSGHYIW VPSPEKL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000000901.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6 EMBL AAH94368.1. Tissue: Brain EMBL AAH94368.1.
[3]	Whitehead S. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000000901.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC094368 mRNA. Translation: AAH94368.1. BX005480 Genomic DNA. Translation: CAM15070.1.
IPI	IPI00623890.
RefSeq	NP_058027.1. NM_016747.3.
UniGene	Mm.4615.
3D structure databases
ProteinModelPortal	Q52KF7.
SMR	Q52KF7. Positions 126-817.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q52KF7. 1 interaction.
STRING	Q52KF7.
Proteomic databases
PRIDE	Q52KF7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000000901; ENSMUSP00000000901; ENSMUSG00000000881.
GeneID	53310.
KEGG	mmu:53310.
UCSC	uc009twp.2. mouse.
Organism-specific databases
CTD	1741.
MGI	MGI:1888986. Dlg3.
Phylogenomic databases
GeneTree	ENSGT00560000076879.
HOVERGEN	HBG107814.
Gene expression databases
ArrayExpress	Q52KF7.
Bgee	Q52KF7.
Genevestigator	Q52KF7.
Family and domain databases
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR016313. M-assoc_guanylate_kinase. IPR019590. MAGUK_PEST_N. IPR001478. PDZ/DHR/GLGF. IPR019583. PDZ_assoc. IPR001452. SH3_domain. [Graphical view]
KO	K12075.
Pfam	PF00625. Guanylate_kin. 1 hit. PF10608. MAGUK_N_PEST. 1 hit. PF00595. PDZ. 3 hits. PF10600. PDZ_assoc. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
PIRSF	PIRSF001741. MAGUK_DLGH. 1 hit.
SMART	SM00072. GuKc. 1 hit. SM00228. PDZ. 3 hits. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF50156. PDZ. 3 hits. SSF50044. SH3. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. PS50106. PDZ. 3 hits. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q52KF7_MOUSE

Accession

Primary (citable) accession number: Q52KF7

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)