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Protein

Uncharacterized protein R02095

Gene

R02095

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi261 – 2688ATPSequence Analysis

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorus-oxygen lyase activity Source: InterPro

GO - Biological processi

  1. cyclic nucleotide biosynthetic process Source: InterPro
  2. intracellular signal transduction Source: InterPro
Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-2146-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein R02095
Gene namesi
Ordered Locus Names:R02095
ORF Names:SMc01491
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001976: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10291029Uncharacterized protein R02095PRO_0000074134Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266834.SMc01491.

Structurei

3D structure databases

ProteinModelPortaliQ52999.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 168130Guanylate cyclasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 guanylate cyclase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG3903.
HOGENOMiHOG000295609.
OMAiGHDAKVC.
OrthoDBiEOG61CKW9.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q52999-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MREWCMLRES RTNTPRRAAE RGKRPGGSSV RGGERRIVTA LCYDLVGSTD
60 70 80 90 100
LMHVMDIEDY QELMSAFQLA SKQAIASHSG VMQHEAGDGG VALFPIELEA
110 120 130 140 150
KDAASLAIRA GLGIVEACKR VGREAGQDDL QVRVGIATSV ALVLEGSREG
160 170 180 190 200
WTREPVTGAA LAMAARLQAI TAPNSVLVSE ETRHLAGRSY AFVFQGSKEL
210 220 230 240 250
KGFAAPEKVW RALGHKVGVD RFYAFGRMGG PLINRENELN TIGQLWDGVL
260 270 280 290 300
AGQGSVVLIQ GDAGIGKSRL LREIRRRTRA KRSKLLFFQC LPGGFRSTLH
310 320 330 340 350
PLLNNLPEAV SGSAGQMGPT AAAVAALFER NGIRDPAVVD VFSYLLGAQG
360 370 380 390 400
SRLQSNEDPK AIREKAHRAL LRALEAVCRR GPAVVAVEDV HWIDPTSRDL
410 420 430 440 450
LGEAARIIAK FPVLLVTTSR PSYASEWLDA ANPTRLALRP LDSDETRLAI
460 470 480 490 500
KAKWPEHRLA LLPDLFDATE RISGGVPLFI EEICQWVSQN VEPDTMRLSE
510 520 530 540 550
SANPSHVSAF ESILESRLQQ LGTAREVARA AAVAGTQVTL PLLRALLPDF
560 570 580 590 600
GKSALANAAD TLCETGFLTR IRVPGRTAYG FRHTLIQETI YNAVLRKQRQ
610 620 630 640 650
VLHRRLFTAV NQNRGMAAWI DTGALAEHAE RAGLVEEAVP LFIAAGKESS
660 670 680 690 700
SRSAMIEARQ FLEHALDLCG QMSESDTAEA LKLLALTALG PILIGTVGLS
710 720 730 740 750
SEPARRLYED AVEIARRRPM SEQSQWFPIY WGWWLTGQDF RVMHDRALEV
760 770 780 790 800
RSMLSKANEP EIQLQVNHCI WAIDFNLGRH RETQDAIKAG LALYDEKRAK
810 820 830 840 850
ESRTEFGGHD AKVCGLGQLA LSLWLTGRTK ASDAALSRMI AFTDRIAHAH
860 870 880 890 900
SKAHSLDTEA VSAFYRDDFE RLTEVSARMA DFAKRHKMQS LSGQSLLFSG
910 920 930 940 950
WAEAHRTGLA SGHARFQNGL SLLRELGAVA DLPIYLCMHA TLLGLAGKIE
960 970 980 990 1000
PAIEVVNEAI GRGEETGHAY WLAELHRCRA ILRARAGERK DAVAADLRCA
1010 1020
VEIAESQGAT ALTRRARHSM RELGIVIGR
Length:1,029
Mass (Da):112,710
Last modified:May 30, 2000 - v2
Checksum:i4EA478188B601958
GO

Sequence cautioni

The sequence AAA88525.1 differs from that shown. Reason: Frameshift at positions 311 and 321. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti323 – 3231A → P1 PublicationCurated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591688 Genomic DNA. Translation: CAC46674.1.
M30934 Genomic DNA. Translation: AAA88525.1. Frameshift.
RefSeqiNP_386201.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC46674; CAC46674; SMc01491.
GeneIDi1233761.
KEGGisme:SMc01491.
PATRICi23633627. VBISinMel96828_3551.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591688 Genomic DNA. Translation: CAC46674.1.
M30934 Genomic DNA. Translation: AAA88525.1. Frameshift.
RefSeqiNP_386201.1. NC_003047.1.

3D structure databases

ProteinModelPortaliQ52999.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266834.SMc01491.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC46674; CAC46674; SMc01491.
GeneIDi1233761.
KEGGisme:SMc01491.
PATRICi23633627. VBISinMel96828_3551.

Phylogenomic databases

eggNOGiCOG3903.
HOGENOMiHOG000295609.
OMAiGHDAKVC.
OrthoDBiEOG61CKW9.

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-2146-MONOMER.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  3. Bent A.F., Signer E.R.
    Submitted (NOV-1990) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-483.
    Strain: 1021.

Entry informationi

Entry nameiY2095_RHIME
AccessioniPrimary (citable) accession number: Q52999
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: February 4, 2015
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.