Q52999 (Y2095_RHIME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein R02095

Gene names

Ordered Locus Names:	R02095
ORF Names:	SMc01491

Organism

Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]

Taxonomic identifier

266834 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › Rhizobium meliloti

Protein attributes

Sequence length	1029 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 guanylate cyclase domain.
Sequence caution	The sequence AAA88525.1 differs from that shown. Reason: Frameshift at positions 311 and 321.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cyclic nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphorus-oxygen lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1029	1029	Uncharacterized protein R02095		PRO_0000074134
Regions
	Domain	39 – 168	130	Guanylate cyclase
	Nucleotide binding	261 – 268	8	ATP Potential
Experimental info
	Sequence conflict	323	1	A → P Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q52999 [UniParc]. Last modified May 30, 2000. Version 2. Checksum: 4EA478188B601958	FASTA	1,029	112,710
	10 20 30 40 50 60 MREWCMLRES RTNTPRRAAE RGKRPGGSSV RGGERRIVTA LCYDLVGSTD LMHVMDIEDY 70 80 90 100 110 120 QELMSAFQLA SKQAIASHSG VMQHEAGDGG VALFPIELEA KDAASLAIRA GLGIVEACKR 130 140 150 160 170 180 VGREAGQDDL QVRVGIATSV ALVLEGSREG WTREPVTGAA LAMAARLQAI TAPNSVLVSE 190 200 210 220 230 240 ETRHLAGRSY AFVFQGSKEL KGFAAPEKVW RALGHKVGVD RFYAFGRMGG PLINRENELN 250 260 270 280 290 300 TIGQLWDGVL AGQGSVVLIQ GDAGIGKSRL LREIRRRTRA KRSKLLFFQC LPGGFRSTLH 310 320 330 340 350 360 PLLNNLPEAV SGSAGQMGPT AAAVAALFER NGIRDPAVVD VFSYLLGAQG SRLQSNEDPK 370 380 390 400 410 420 AIREKAHRAL LRALEAVCRR GPAVVAVEDV HWIDPTSRDL LGEAARIIAK FPVLLVTTSR 430 440 450 460 470 480 PSYASEWLDA ANPTRLALRP LDSDETRLAI KAKWPEHRLA LLPDLFDATE RISGGVPLFI 490 500 510 520 530 540 EEICQWVSQN VEPDTMRLSE SANPSHVSAF ESILESRLQQ LGTAREVARA AAVAGTQVTL 550 560 570 580 590 600 PLLRALLPDF GKSALANAAD TLCETGFLTR IRVPGRTAYG FRHTLIQETI YNAVLRKQRQ 610 620 630 640 650 660 VLHRRLFTAV NQNRGMAAWI DTGALAEHAE RAGLVEEAVP LFIAAGKESS SRSAMIEARQ 670 680 690 700 710 720 FLEHALDLCG QMSESDTAEA LKLLALTALG PILIGTVGLS SEPARRLYED AVEIARRRPM 730 740 750 760 770 780 SEQSQWFPIY WGWWLTGQDF RVMHDRALEV RSMLSKANEP EIQLQVNHCI WAIDFNLGRH 790 800 810 820 830 840 RETQDAIKAG LALYDEKRAK ESRTEFGGHD AKVCGLGQLA LSLWLTGRTK ASDAALSRMI 850 860 870 880 890 900 AFTDRIAHAH SKAHSLDTEA VSAFYRDDFE RLTEVSARMA DFAKRHKMQS LSGQSLLFSG 910 920 930 940 950 960 WAEAHRTGLA SGHARFQNGL SLLRELGAVA DLPIYLCMHA TLLGLAGKIE PAIEVVNEAI 970 980 990 1000 1010 1020 GRGEETGHAY WLAELHRCRA ILRARAGERK DAVAADLRCA VEIAESQGAT ALTRRARHSM RELGIVIGR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021." Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D. , Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F. Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
[2]	"The composite genome of the legume symbiont Sinorhizobium meliloti." Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. , Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S., Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I., Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S., Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C., Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R., Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H., Wong K., Yeh K.-C., Batut J. Science 293:668-672(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
[3]	Bent A.F., Signer E.R. Submitted (NOV-1990) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-483. Strain: 1021.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL591688 Genomic DNA. Translation: CAC46674.1. M30934 Genomic DNA. Translation: AAA88525.1. Frameshift.
RefSeq	NP_386201.1. NC_003047.1.
3D structure databases
ProteinModelPortal	Q52999.
ModBase	Search...
Protein-protein interaction databases
STRING	266834.SMc01491.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAC46674; CAC46674; SMc01491.
GeneID	1233761.
KEGG	sme:SMc01491.
PATRIC	23633627. VBISinMel96828_3551.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3903.
HOGENOM	HOG000295609.
OMA	GGHDAKV.
ProtClustDB	CLSK783000.
Enzyme and pathway databases
BioCyc	SMEL266834:GJF6-2146-MONOMER.
Family and domain databases
Gene3D	3.30.70.1230. 1 hit.
InterPro	IPR001054. A/G_cyclase. [Graphical view]
Pfam	PF00211. Guanylate_cyc. 1 hit. [Graphical view]
SMART	SM00044. CYCc. 1 hit. [Graphical view]
SUPFAM	SSF55073. A/G_cyclase. 1 hit.
PROSITE	PS50125. GUANYLATE_CYCLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y2095_RHIME

Accession

Primary (citable) accession number: Q52999

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 30, 2000
Last modified:	May 1, 2013
This is version 86 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program