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Protein

Probable enoyl-CoA hydratase

Gene

fadB1

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Could possibly oxidize fatty acids using specific components.By similarity

Catalytic activityi

(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Fatty acid metabolism, Lipid metabolism

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-377-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable enoyl-CoA hydratase (EC:4.2.1.17)
Gene namesi
Name:fadB1
Ordered Locus Names:R00366
ORF Names:SMc01153
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001976 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 257257Probable enoyl-CoA hydratasePRO_0000109344Add
BLAST

Proteomic databases

PRIDEiQ52995.

Interactioni

Protein-protein interaction databases

STRINGi266834.SMc01153.

Structurei

3D structure databases

ProteinModelPortaliQ52995.
SMRiQ52995. Positions 14-255.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105E39. Bacteria.
COG1024. LUCA.
HOGENOMiHOG000027939.
KOiK01692.
OMAiTLIVETR.
OrthoDBiEOG6M9F0M.

Family and domain databases

Gene3Di3.90.226.10. 1 hit.
InterProiIPR029045. ClpP/crotonase-like_dom.
IPR001753. Crotonase_core_superfam.
IPR018376. Enoyl-CoA_hyd/isom_CS.
[Graphical view]
PfamiPF00378. ECH_1. 1 hit.
[Graphical view]
SUPFAMiSSF52096. SSF52096. 1 hit.
PROSITEiPS00166. ENOYL_COA_HYDRATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q52995-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYETLLVET QGRVGLITLN RPQALNALNA VLMRELDAAL KAFDADRAVG
60 70 80 90 100
AIVLAGSEKA FAAGADIKEM QGLDFVDGYL ADFLGGWEHV ANARKPMIAA
110 120 130 140 150
VSGFALGGGC ELAMMCDFII ASETAKFGQP EITLGVIPGM GGSQRLTRAV
160 170 180 190 200
GKAKAMDLIL TGRMMDAAEA ERSGLVSRVV APDRLLEEAL GAAEKIASFS
210 220 230 240 250
LPAAMMAKEA VNRSLELTLA EGLRFERRLF QSLFATEDQK EGMAAFVAKR

KAEFKHR
Length:257
Mass (Da):27,472
Last modified:May 30, 2000 - v2
Checksum:i971970C6C6E780A7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti129 – 1291Q → L in AAA91095 (PubMed:7751302).Curated
Sequence conflicti196 – 1961I → T in AAA91095 (PubMed:7751302).Curated
Sequence conflicti220 – 2201A → T in AAA91095 (PubMed:7751302).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39265 Genomic DNA. Translation: AAA91095.1.
AL591688 Genomic DNA. Translation: CAC41803.1.
RefSeqiNP_384472.1. NC_003047.1.
WP_010968532.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC41803; CAC41803; SMc01153.
GeneIDi1232000.
KEGGisme:SMc01153.
PATRICi23629937. VBISinMel96828_1738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39265 Genomic DNA. Translation: AAA91095.1.
AL591688 Genomic DNA. Translation: CAC41803.1.
RefSeqiNP_384472.1. NC_003047.1.
WP_010968532.1. NC_003047.1.

3D structure databases

ProteinModelPortaliQ52995.
SMRiQ52995. Positions 14-255.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266834.SMc01153.

Proteomic databases

PRIDEiQ52995.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC41803; CAC41803; SMc01153.
GeneIDi1232000.
KEGGisme:SMc01153.
PATRICi23629937. VBISinMel96828_1738.

Phylogenomic databases

eggNOGiENOG4105E39. Bacteria.
COG1024. LUCA.
HOGENOMiHOG000027939.
KOiK01692.
OMAiTLIVETR.
OrthoDBiEOG6M9F0M.

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-377-MONOMER.

Family and domain databases

Gene3Di3.90.226.10. 1 hit.
InterProiIPR029045. ClpP/crotonase-like_dom.
IPR001753. Crotonase_core_superfam.
IPR018376. Enoyl-CoA_hyd/isom_CS.
[Graphical view]
PfamiPF00378. ECH_1. 1 hit.
[Graphical view]
SUPFAMiSSF52096. SSF52096. 1 hit.
PROSITEiPS00166. ENOYL_COA_HYDRATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The dnaA gene of Rhizobium meliloti lies within an unusual gene arrangement."
    Margolin W., Bramhill D., Long S.R.
    J. Bacteriol. 177:2892-2900(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 1021.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.

Entry informationi

Entry nameiECHH_RHIME
AccessioniPrimary (citable) accession number: Q52995
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: November 11, 2015
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.