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Protein

General L-amino acid transport system permease protein AapM

Gene

aapM

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Protein family/group databases

TCDBi3.A.1.3.8. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
General L-amino acid transport system permease protein AapM
Gene namesi
Name:aapM
Ordered Locus Names:RL2202
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000006575 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 64HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei117 – 137HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei144 – 164HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei179 – 199HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei220 – 240HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei250 – 270HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei319 – 339HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei347 – 367HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000599381 – 384General L-amino acid transport system permease protein AapMAdd BLAST384

Interactioni

Protein-protein interaction databases

STRINGi216596.RL2202.

Structurei

3D structure databases

ProteinModelPortaliQ52814.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini175 – 364ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST190

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DRP. Bacteria.
COG0765. LUCA.
HOGENOMiHOG000125341.
KOiK09971.
OMAiLVFWVFC.
OrthoDBiPOG091H0AU2.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q52814-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVADKPFVR TSILAAEPPP PGERGAVAWI RRNLLATPKD VILTILALAL
60 70 80 90 100
IAWAVPHLVN WLFIQAVWSG PDRTFCATTL QGGIQPDGWS GACWAFISAK
110 120 130 140 150
YDQFIFGRYP LGERWRPAIV GILFILLLVP MLIPSAPRKG LNAILLFAVL
160 170 180 190 200
PVIAFWLLHG GFGLEVVETP LWGGLMVTLV LSFVGIAVSL PVGILLALGR
210 220 230 240 250
RSRMPVIRML CVTFIEVIRG VPLITVLFMA SVMLPLFLPT GWNVDKLLRA
260 270 280 290 300
LIGVSIFTSA YMAEVIRGGL QAIPKGQFEG ADSLGLGYWQ KTRLIIMPQA
310 320 330 340 350
IKLVIPSIVN TFIGTFKDTS LVTIIGMFDL LGIVKLNFSD ANWASAVTPI
360 370 380
TGLIFAGFIF WLFCFGMSRY SGFMERHLDT GHKR
Length:384
Mass (Da):42,150
Last modified:November 1, 1996 - v1
Checksum:i6D4927918F60872F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X82596 Genomic DNA. Translation: CAA57935.1.
AM236080 Genomic DNA. Translation: CAK07694.1.
RefSeqiWP_011651799.1. NC_008380.1.

Genome annotation databases

EnsemblBacteriaiCAK07694; CAK07694; RL2202.
KEGGirle:RL2202.
PATRICi23141007. VBIRhiLeg32091_3428.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X82596 Genomic DNA. Translation: CAA57935.1.
AM236080 Genomic DNA. Translation: CAK07694.1.
RefSeqiWP_011651799.1. NC_008380.1.

3D structure databases

ProteinModelPortaliQ52814.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216596.RL2202.

Protein family/group databases

TCDBi3.A.1.3.8. the atp-binding cassette (abc) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAK07694; CAK07694; RL2202.
KEGGirle:RL2202.
PATRICi23141007. VBIRhiLeg32091_3428.

Phylogenomic databases

eggNOGiENOG4105DRP. Bacteria.
COG0765. LUCA.
HOGENOMiHOG000125341.
KOiK09971.
OMAiLVFWVFC.
OrthoDBiPOG091H0AU2.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAAPM_RHIL3
AccessioniPrimary (citable) accession number: Q52814
Secondary accession number(s): Q1MH73
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.