Q52402 (AARD_PROST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transport ATP-binding protein AarD

Gene names

Name:

aarD

Organism

Providencia stuartii

Taxonomic identifier

588 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Providencia

Protein attributes

Sequence length	588 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein Probable.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Nucleotide-binding
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC cysteine transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 588	588	Transport ATP-binding protein AarD		PRO_0000091919
Regions
	Transmembrane	29 – 49	21	Helical; Potential
	Transmembrane	62 – 82	21	Helical; Potential
	Transmembrane	149 – 169	21	Helical; Potential
	Transmembrane	170 – 190	21	Helical; Potential
	Transmembrane	250 – 270	21	Helical; Potential
	Transmembrane	276 – 296	21	Helical; Potential
	Domain	24 – 316	293	ABC transmembrane type-1
	Domain	350 – 583	234	ABC transporter
	Nucleotide binding	383 – 390	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q52402 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 3CCE18DDA53B7D36	FASTA	588	65,778
	10 20 30 40 50 60 MDKTRQTELV RWLKQHSTSA KRWLRISMLL GVVSGLLIIA QAWFLAVILQ ALIMEHTPRE 70 80 90 100 110 120 QLLTPFILLL AVFVLRALLT VIRERVGFRC GQVVRQEVRN MVLNKLQALG PVWVKGKPAG 130 140 150 160 170 180 SWATIVLEQI EDMQEYYSRY LPQMYLAGII PIMILIAIFP FNWAAALILF ATAPLIPIFM 190 200 210 220 230 240 ALVGLGAADA NRRNFVALGR LSGSFLDRLR GLDTLRLFFR EKAEVQQIRE STEDFRSRTM 250 260 270 280 290 300 EVLRMAFLSS GVLEFFASIS IAIVAVYFGF SYLGELNFGS YGLPVTMFAG FLALILSPEF 310 320 330 340 350 360 FQPLRDLGTY YHAKAQAVGA AESLVTLLES DGEQKTETGD KTPQDKPIQI EANKLEIYSH 370 380 390 400 410 420 DGQRLVGPLD FTIEPQQRIA VFGQSGAGKS SLLNLLLGFL PYKGSIKING DELKELCPDK 430 440 450 460 470 480 WRALIGWVGQ NPHLPEQTLI ENICLGKPTA SEAEIQQAID DAYVSEFLPM LPDGLNTRLG 490 500 510 520 530 540 DYAARLSVGQ AQRVAVARTL LKPSRILLLD EPAASLDAHS EKRVMHTLNQ LAQQQTTIMV 550 560 570 580 THLLEETVNY DQIWVMANGQ IIQRGHYAQL SQSEGPFARL LAHRSEEL

References

[1]

"aarD, a Providencia stuartii homologue of cydD: role in 2'-N-acetyltransferase expression, cell morphology and growth in the presence of an extracellular factor." Macinga D.R., Rather P.N. Mol. Microbiol. 19:511-520(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: PR50.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U30383 Genomic DNA. Translation: AAB18930.1.
PIR	S70900.
3D structure databases
ProteinModelPortal	Q52402.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR014216. ABC_transptr_CydD. IPR001140. ABC_transptr_TM_dom. IPR011527. ABC_transptrTM_dom_typ1. [Graphical view]
Pfam	PF00664. ABC_membrane. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF90123. ABC_TM_1. 1 hit.
TIGRFAMs	TIGR02857. CydD. 1 hit.
PROSITE	PS50929. ABC_TM1F. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AARD_PROST

Accession

Primary (citable) accession number: Q52402

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program