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Protein

Cytochrome c4

Gene

cc4

Organism
Pseudomonas stutzeri (Pseudomonas perfectomarina)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei34Heme 1 (covalent)1
Binding sitei37Heme 1 (covalent)1
Metal bindingi38Iron (heme 1 axial ligand)1
Metal bindingi86Iron (heme 1 axial ligand)1
Binding sitei139Heme 2 (covalent)1
Binding sitei142Heme 2 (covalent)1
Metal bindingi143Iron (heme 2 axial ligand)1
Metal bindingi187Iron (heme 2 axial ligand)1

GO - Molecular functioni

Keywordsi

Biological processElectron transport, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c4
Gene namesi
Name:cc4
OrganismiPseudomonas stutzeri (Pseudomonas perfectomarina)
Taxonomic identifieri316 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

Pathology & Biotechi

Chemistry databases

DrugBankiDB04077 Glycerol
DB03317 Heme C
DB03754 Tris

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Add BLAST20
ChainiPRO_000000650921 – 210Cytochrome c4Add BLAST190

Post-translational modificationi

Binds 2 heme groups per subunit.

Structurei

Secondary structure

1210
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi24 – 28Combined sources5
Helixi32 – 34Combined sources3
Helixi35 – 38Combined sources4
Helixi57 – 71Combined sources15
Helixi84 – 86Combined sources3
Turni87 – 92Combined sources6
Helixi95 – 107Combined sources13
Helixi117 – 129Combined sources13
Helixi132 – 134Combined sources3
Helixi140 – 143Combined sources4
Helixi151 – 153Combined sources3
Helixi163 – 174Combined sources12
Turni180 – 184Combined sources5
Helixi186 – 191Combined sources6
Helixi196 – 207Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ETPX-ray2.20A/B21-210[»]
1M6ZX-ray1.35A/B/C/D21-210[»]
1M70X-ray1.25A/B/C/D21-210[»]
ProteinModelPortaliQ52369
SMRiQ52369
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ52369

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4106RE7 Bacteria
COG2863 LUCA

Family and domain databases

Gene3Di1.10.760.10, 2 hits
InterProiView protein in InterPro
IPR009056 Cyt_c-like_dom
IPR036909 Cyt_c-like_dom_sf
IPR024167 Cytochrome_c4-like
PfamiView protein in Pfam
PF00034 Cytochrom_C, 2 hits
PIRSFiPIRSF000005 Cytochrome_c4, 1 hit
SUPFAMiSSF46626 SSF46626, 2 hits
PROSITEiView protein in PROSITE
PS51007 CYTC, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q52369-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKVLVSLLL TLGITGMAHA AGDAEAGQGK VAVCGACHGV DGNSPAPNFP
60 70 80 90 100
KLAGQGERYL LKQLQDIKAG STPGAPEGVG RKVLEMTGML DPLSDQDLED
110 120 130 140 150
IAAYFSSQKG SVGYADPALA KQGEKLFRGG KLDQGMPACT GCHAPNGVGN
160 170 180 190 200
DLAGFPKLGG QHAAYTAKQL TDFREGNRTN DGDTMIMRGV AAKLSNKDIE
210
ALSSYIQGLH
Length:210
Mass (Da):21,742
Last modified:November 1, 1996 - v1
Checksum:iC33CF23A6FAA6F99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U05988 Genomic DNA Translation: AAA20247.1
RefSeqiWP_014818660.1, NZ_POUV01000003.1

Similar proteinsi

Entry informationi

Entry nameiCYC4_PSEST
AccessioniPrimary (citable) accession number: Q52369
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure
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Main funding by: National Institutes of Health