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Protein

Glucose-1-phosphatase

Gene

agp

Organism
Providencia rettgeri
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei41SubstrateBy similarity1
Active sitei42NucleophileBy similarity1
Binding sitei45SubstrateBy similarity1
Binding sitei118SubstrateBy similarity1
Binding sitei220SubstrateBy similarity1
Active sitei315Proton donorBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-1-phosphatase (EC:3.1.3.10)
Short name:
G1Pase
Gene namesi
Name:agp
OrganismiProvidencia rettgeri
Taxonomic identifieri587 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaeProvidencia

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000002395024 – 417Glucose-1-phosphataseAdd BLAST394

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ52309.
SMRiQ52309.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Keywords - Domaini

Signal

Family and domain databases

CDDicd07061. HP_HAP_like. 1 hit.
Gene3Di3.40.50.1240. 3 hits.
InterProiIPR033379. Acid_Pase_AS.
IPR000560. His_Pase_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q52309-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYKVLTLCL SAALFAPIAP TMASTDNQAD MVLDQVLVLS RHNLRTPIVN
60 70 80 90 100
TGILTEVTDK KWPDWDAKSG YLTTQGGALE VYMGHYFREW IDQNKLLADE
110 120 130 140 150
LCPTSNEDIY LYTNSLQRTI ATAQFFAAGA FPGCKVNIHH QPEIGKMDPV
160 170 180 190 200
FNPIITNGSP EFKQKALAAM DDYLKGLSLK AGYEELDTVL NIKDSQKCKT
210 220 230 240 250
DKLCNLDSQK NSFIIEADKE PGVSGPLKIA NSAVDAIDLQ YYEGFPADQV
260 270 280 290 300
AWGLVDTPEK WKKLNTLKNA YQETLFTPKI IAKNVAHPIL NYIDKGFVSV
310 320 330 340 350
DKGETAKFIF LVGHDSNIAS LMSAMDFKPY QLAQQYEHTP IGGKLVFQRW
360 370 380 390 400
TDKQTKKDFM KVEYVYQTAD QLRDNAYLSL ETPPKHVTLE LKDCPVDKNG
410
YCSWEDFQKV MAKALEQ
Length:417
Mass (Da):46,941
Last modified:November 1, 1996 - v1
Checksum:i8CC4CA4F55DBFB90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68201 Genomic DNA. Translation: CAA48288.1.
PIRiS25627.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68201 Genomic DNA. Translation: CAA48288.1.
PIRiS25627.

3D structure databases

ProteinModelPortaliQ52309.
SMRiQ52309.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd07061. HP_HAP_like. 1 hit.
Gene3Di3.40.50.1240. 3 hits.
InterProiIPR033379. Acid_Pase_AS.
IPR000560. His_Pase_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAGP_PRORE
AccessioniPrimary (citable) accession number: Q52309
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.