Q52309 (AGP_PRORE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucose-1-phosphatase
Short name=G1Pase
EC=3.1.3.10

Gene names

Name:

agp

Organism

Providencia rettgeri

Taxonomic identifier

587 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Providencia

Protein attributes

Sequence length	417 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.
Subunit structure	Homodimer By similarity.
Subcellular location	Periplasm By similarity.
Sequence similarities	Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Hydrolase
Gene Ontology (GO)
Cellular_component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	acid phosphatase activity Inferred from electronic annotation. Source: InterPro glucose-1-phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 417	394	Glucose-1-phosphatase		PRO_0000023950
Sites
	Active site	42	1	Nucleophile By similarity
	Active site	315	1	Proton donor By similarity
	Binding site	41	1	Substrate By similarity
	Binding site	45	1	Substrate By similarity
	Binding site	118	1	Substrate By similarity
	Binding site	220	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q52309 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 8CC4CA4F55DBFB90	FASTA	417	46,941
	10 20 30 40 50 60 MKYKVLTLCL SAALFAPIAP TMASTDNQAD MVLDQVLVLS RHNLRTPIVN TGILTEVTDK 70 80 90 100 110 120 KWPDWDAKSG YLTTQGGALE VYMGHYFREW IDQNKLLADE LCPTSNEDIY LYTNSLQRTI 130 140 150 160 170 180 ATAQFFAAGA FPGCKVNIHH QPEIGKMDPV FNPIITNGSP EFKQKALAAM DDYLKGLSLK 190 200 210 220 230 240 AGYEELDTVL NIKDSQKCKT DKLCNLDSQK NSFIIEADKE PGVSGPLKIA NSAVDAIDLQ 250 260 270 280 290 300 YYEGFPADQV AWGLVDTPEK WKKLNTLKNA YQETLFTPKI IAKNVAHPIL NYIDKGFVSV 310 320 330 340 350 360 DKGETAKFIF LVGHDSNIAS LMSAMDFKPY QLAQQYEHTP IGGKLVFQRW TDKQTKKDFM 370 380 390 400 410 KVEYVYQTAD QLRDNAYLSL ETPPKHVTLE LKDCPVDKNG YCSWEDFQKV MAKALEQ

References

[1]	Riccio M.L., Chiesurin A., Lombardi G., Satta G. Submitted (SEP-1992) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: PV7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X68201 Genomic DNA. Translation: CAA48288.1.
PIR	S25627.
3D structure databases
ProteinModelPortal	Q52309.
SMR	Q52309. Positions 29-416.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000560. His_Pase_superF_clade-2. [Graphical view]
Pfam	PF00328. His_Phos_2. 1 hit. [Graphical view]
PROSITE	PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AGP_PRORE

Accession

Primary (citable) accession number: Q52309

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 1, 1996
Last modified:	June 13, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program