Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q51P78

- ATG12_MAGO7

UniProt

Q51P78 - ATG12_MAGO7

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ubiquitin-like protein ATG12

Gene

ATG12

Organism
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).By similarity

GO - Biological processi

  1. autophagic vacuole assembly Source: InterPro
  2. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Autophagy, Protein transport, Transport, Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-like protein ATG12
Alternative name(s):
Autophagy-related protein 12
Gene namesi
Name:ATG12
ORF Names:MGG_00598
OrganismiMagnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
Taxonomic identifieri242507 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeMagnaporthalesMagnaporthaceaeMagnaporthe
ProteomesiUP000009058: Chromosome 5

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
  2. membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 181181Ubiquitin-like protein ATG12PRO_0000212481Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki181 – 181Glycyl lysine isopeptide (Gly-Lys) (interchain with K-162 in ATG5)By similarity

Keywords - PTMi

Isopeptide bond

Interactioni

Subunit structurei

Forms a conjugate with ATG5.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ51P78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG12 family.Curated

Phylogenomic databases

eggNOGiNOG236266.
InParanoidiQ51P78.
KOiK08336.
OrthoDBiEOG7ZSJ5R.

Family and domain databases

InterProiIPR007242. Atg12.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR13385. PTHR13385. 1 hit.
PfamiPF04110. APG12. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.

Sequencei

Sequence statusi: Complete.

Q51P78-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSPPTRYTR NPQLRRPSLS TPTPPPPSSS STAPASSSAT PIPDDAPDAD
60 70 80 90 100
DNDGSPPSPD LPLTMSASVM LTQLPRDATA ALATAGEFPA DQKVVVRFKP
110 120 130 140 150
VGGSAPALRK ELCKISAAQR FEAVVAYLRR TLKVGNGESV FLYINSTFAP
160 170 180
ALDEIVGNLH RCFKDSNGQL NVSYSMTPAF G
Length:181
Mass (Da):19,118
Last modified:June 7, 2005 - v1
Checksum:i86A3BC56930DE80B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM001235 Genomic DNA. Translation: EHA48856.1.
RefSeqiXP_003718440.1. XM_003718392.1.

Genome annotation databases

EnsemblFungiiMGG_00598T0; MGG_00598T0; MGG_00598.
GeneIDi2674234.
KEGGimgr:MGG_00598.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM001235 Genomic DNA. Translation: EHA48856.1 .
RefSeqi XP_003718440.1. XM_003718392.1.

3D structure databases

ProteinModelPortali Q51P78.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii MGG_00598T0 ; MGG_00598T0 ; MGG_00598 .
GeneIDi 2674234.
KEGGi mgr:MGG_00598.

Phylogenomic databases

eggNOGi NOG236266.
InParanoidi Q51P78.
KOi K08336.
OrthoDBi EOG7ZSJ5R.

Family and domain databases

InterProi IPR007242. Atg12.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
PANTHERi PTHR13385. PTHR13385. 1 hit.
Pfami PF04110. APG12. 1 hit.
[Graphical view ]
SUPFAMi SSF54236. SSF54236. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 70-15 / ATCC MYA-4617 / FGSC 8958.

Entry informationi

Entry nameiATG12_MAGO7
AccessioniPrimary (citable) accession number: Q51P78
Secondary accession number(s): A4REQ6, G4NB95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: June 7, 2005
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3