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Protein

Ferredoxin--nitrite reductase

Gene

nirA

Organism
Phormidium laminosum
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi396 – 3961Iron-sulfur (4Fe-4S)By similarity
Metal bindingi402 – 4021Iron-sulfur (4Fe-4S)By similarity
Metal bindingi437 – 4371Iron-sulfur (4Fe-4S)By similarity
Metal bindingi441 – 4411Iron (siroheme axial ligand)By similarity
Metal bindingi441 – 4411Iron-sulfur (4Fe-4S)By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Nitrate assimilation, Transport

Keywords - Ligandi

4Fe-4S, Heme, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin--nitrite reductase (EC:1.7.7.1)
Gene namesi
Name:nirA
Synonyms:nir
OrganismiPhormidium laminosum
Taxonomic identifieri32059 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesPhormidium

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 510510Ferredoxin--nitrite reductasePRO_0000199956Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ51879.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.90.480.10. 2 hits.
InterProiIPR005117. NiRdtase/SiRdtase_haem-b_fer.
IPR006067. NO2/SO3_Rdtase_4Fe4S_dom.
IPR006066. NO2/SO3_Rdtase_FeS/sirohaem_BS.
[Graphical view]
PfamiPF01077. NIR_SIR. 2 hits.
PF03460. NIR_SIR_ferr. 2 hits.
[Graphical view]
PRINTSiPR00397. SIROHAEM.
SUPFAMiSSF55124. SSF55124. 2 hits.
PROSITEiPS00365. NIR_SIR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q51879-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSTVPAETS LNKFEKLKSE KDGLAVKSEL EDFARLGWEA MDETDRDHRL
60 70 80 90 100
RWMGVFFRPV SQGKFMLRMR IPNGILTSGQ IRVLAEVVER YGEDGNADIT
110 120 130 140 150
TRPNLQLRGI RLEDIPDIFR RFEQAGLTSI QSGMDNVRNI TGSPVAGIDA
160 170 180 190 200
DELIDTRGLV RKVQDMITNN GEGNPSFSNL PRKFNIAIAG CRDNSVHAEI
210 220 230 240 250
NDIAFVPAYK DGKLGFNVLV GGFFSAKRCE AAVPLNAWVD PRDVVALCEA
260 270 280 290 300
ILIVYRITGC GANRQKSRLM WLIDEWGMDK FRAEVEQQLG HPLQTAAPKD
310 320 330 340 350
EILWDKRDHI GIHAQKKPGL NYVGLLVPVG RLYAPMFDLA RIAEVYGDGE
360 370 380 390 400
MRLTVERKRD HSRTCPMSSV ASLLKEPLLE KFSVSPGLLV RSLVSCTGAQ
410 420 430 440 450
FCNFALIETK NRAMALIREL ESELELARPV RIHWTGCPNS CGQPQVADIG
460 470 480 490 500
LMGTKVRKDG KATEGVDLYM GGKVGKHAEL GTCVQKGIPC DDLKPILRNL
510
LIEHFGARPK
Length:510
Mass (Da):56,709
Last modified:November 1, 1996 - v1
Checksum:iD4BB0816EABD9C80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z19598 Genomic DNA. Translation: CAA79655.1.
PIRiS56640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z19598 Genomic DNA. Translation: CAA79655.1.
PIRiS56640.

3D structure databases

ProteinModelPortaliQ51879.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.90.480.10. 2 hits.
InterProiIPR005117. NiRdtase/SiRdtase_haem-b_fer.
IPR006067. NO2/SO3_Rdtase_4Fe4S_dom.
IPR006066. NO2/SO3_Rdtase_FeS/sirohaem_BS.
[Graphical view]
PfamiPF01077. NIR_SIR. 2 hits.
PF03460. NIR_SIR_ferr. 2 hits.
[Graphical view]
PRINTSiPR00397. SIROHAEM.
SUPFAMiSSF55124. SSF55124. 2 hits.
PROSITEiPS00365. NIR_SIR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Isolation, sequence and expression in Escherichia coli of the nitrite reductase gene from the filamentous, thermophilic cyanobacterium Phormidium laminosum."
    Merchan F., Prieto R., Kindle K.L., Llama M.J., Serra J.L., Fernandez E.
    Plant Mol. Biol. 27:1037-1042(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: OH-1-P-CL1.

Entry informationi

Entry nameiNIR_PHOLA
AccessioniPrimary (citable) accession number: Q51879
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 1, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.