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Q51841 (PPNK_PORGI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase

Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23
Gene names
Name:ppnK
Synonyms:put
Ordered Locus Names:PG_0629
OrganismPorphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]
Taxonomic identifier242619 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas

Protein attributes

Sequence length288 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 288288Probable inorganic polyphosphate/ATP-NAD kinase HAMAP-Rule MF_00361
PRO_0000120645

Experimental info

Sequence conflict81 – 9212HQIGV…IPVLG → IKSAFRRSLSWA in CAA65865. Ref.1
Sequence conflict2691R → G in CAA65865. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q51841 [UniParc].

Last modified October 3, 2003. Version 2.
Checksum: 49C6D0570B5AE8B7

FASTA28831,731
        10         20         30         40         50         60 
MKKIAIFGSR HKSEQGASIK ALILKLEEAG TPLYIERKFL SFLKQDLDFH PAICGVIDTL 

        70         80         90        100        110        120 
PEHIDYVICM GGDGTFLRTA HQIGVSQIPV LGVNTGRLGF LTDVDCHEAS ELITRLLDGD 

       130        140        150        160        170        180 
FTIETRSLLE VTEDNGSSPS YALNEAAILK RETGSMIRVN ACLNDDYLAA YDADGLVVAT 

       190        200        210        220        230        240 
PSGSTAYSLS GNGPIIMPAC RNFVLTPIAP HSLNMRPLVV PDDTVIRLEV DSRSRNYLLV 

       250        260        270        280 
LDGRTRTLPC DTSILLKRAP HTLRMIRLRP HSFAETLRRK LMWGAAVR 

« Hide

References

« Hide 'large scale' references
[1]"Cloning of pyridoxal phosphate from P.gingivalis."
Wallace A.M., Roberts I.S.
Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC BAA-308 / W83.
[2]"Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83."
Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E., Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J., Granger D., Tettelin H. expand/collapse author list , Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E., Fraser C.M.
J. Bacteriol. 185:5591-5601(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-308 / W83.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X97228 Genomic DNA. Translation: CAA65865.1.
AE015924 Genomic DNA. Translation: AAQ65813.1.
RefSeqNP_904914.1. NC_002950.2.

3D structure databases

ProteinModelPortalQ51841.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING242619.PG0629.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAQ65813; AAQ65813; PG_0629.
GeneID2552505.
KEGGpgi:PG0629.
PATRIC22978338. VBIPorGin134034_0575.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0061.
KOK00858.
OMAGMVELRV.
OrthoDBEOG6PZXDR.
ProtClustDBPRK01911.

Enzyme and pathway databases

BioCycPGIN242619:GHX8-576-MONOMER.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK_PORGI
AccessionPrimary (citable) accession number: Q51841
Entry history
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: October 3, 2003
Last modified: February 19, 2014
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families