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Q51826 (FIMA3_PORGN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Major fimbrial subunit protein type-3
Alternative name(s):
Fimbrillin
Short name=Fimbrilin
Major fimbrial subunit protein type III
Gene names
Name:fimA
OrganismPorphyromonas gingivalis
Taxonomic identifier837 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas

Protein attributes

Sequence length353 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Fimbrillin is the structural subunit of the fimbriae, that are filamentous appendages on the cell surface. Fimbriae of P.gingivalis are recognized as a major virulence factor as they mediate cell adhesion and play an important role in invasion of periodontal tissues. Ref.2

Subcellular location

Fimbrium.

Sequence similarities

Belongs to the P.gingivalis fimbrillin family.

Ontologies

Keywords
   Biological processCell adhesion
Virulence
   Cellular componentFimbrium
Gene Ontology (GO)
   Biological_processcell adhesion

Inferred from electronic annotation. Source: UniProtKB-KW

pathogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentpilus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionstructural molecule activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Propeptide1 – 1010 By similarity
PRO_0000009164
Chain11 – 353343Major fimbrial subunit protein type-3
PRO_0000009165

Sequences

Sequence LengthMass (Da)Tools
Q51826 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 7FBE4FBF427EA2AB

FASTA35338,024
        10         20         30         40         50         60 
MVLKTSNPNR AFGNAGDEAK VAKLTVMVYK GEQQEAIKSV ENAIKVENIK CGAGQRTLVV 

        70         80         90        100        110        120 
MANTGGMELA GKTLAEVKAL TTELTEGNQE AAGLIMTAEP VEVTLVAGNN YYGYDGSQGG 

       130        140        150        160        170        180 
NQISQGTPLE IKRVHARIAF TKIEVTMSQS YANKYNFAPE NIYALVAKKK SNLFGASLAN 

       190        200        210        220        230        240 
SDDAYLTGSL TTFNGAYSPA NYTHVDWLGR DYTEIGAATV NTPKGFYVLE STYAQNAGLR 

       250        260        270        280        290        300 
PTILCVKGKL TKHDGTALSS EEMTAAFNAG WIVANNDPTT YYPVLVNFES NNYTYTGEAV 

       310        320        330        340        350 
EKGKIVRNHK FDINLTITGP GTNNPENPIT ESANLNVNCV VAAWKGVVQN VIW 

« Hide

References

[1]"Molecular cloning and sequencing of the fimbrilin gene of Porphyromonas gingivalis strains and characterization of recombinant proteins."
Fujiwara T., Morishima S., Takahashi I., Hamada S.
Biochem. Biophys. Res. Commun. 197:241-247(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 6/26.
[2]"Functional differences among FimA variants of Porphyromonas gingivalis and their effects on adhesion to and invasion of human epithelial cells."
Nakagawa I., Amano A., Kuboniwa M., Nakamura T., Kawabata S., Hamada S.
Infect. Immun. 70:277-285(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, CLASSIFICATION INTO TYPES.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D17801 Genomic DNA. Translation: BAA04627.1.
PIRD60275.
JN0920.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR029141. FimA_N.
IPR008110. Fimbrillin.
[Graphical view]
PfamPF06321. P_gingi_FimA. 1 hit.
[Graphical view]
PRINTSPR01737. FIMBRILLIN.
ProtoNetSearch...

Entry information

Entry nameFIMA3_PORGN
AccessionPrimary (citable) accession number: Q51826
Entry history
Integrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families