Q51802 (VORB_PYRFU) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 68.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Ketoisovalerate oxidoreductase subunit vorB Short name=VOR EC=1.2.7.7 Alternative name(s): 2-oxoisovalerate ferredoxin reductase subunit beta 2-oxoisovalerate oxidoreductase beta chain | ||||
| Gene names |
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| Organism | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | ||||
| Taxonomic identifier | 186497 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus |
Protein attributes
| Sequence length | 311 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Catalytic activity | 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+. |
| Subunit structure | Heterotetramer of one alpha, one beta, one delta and one gamma chain. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Direct protein sequencing Reference proteome |
| Gene Ontology (GO) | |
| Molecular function | 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 311 | 311 | Ketoisovalerate oxidoreductase subunit vorB | PRO_0000099957 | |||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Molecular and phylogenetic characterization of pyruvate and 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga maritima." Kletzin A., Adams M.W.W. J. Bacteriol. 178:248-257(1996) [PubMed: 8550425] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-7. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1. |
| [2] | "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences." Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T. Genetics 152:1299-1305(1999) [PubMed: 10430560] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | X85250 Genomic DNA. Translation: CAA59503.1. AE009950 Genomic DNA. Translation: AAL81092.1. |
| PIR | T45086. |
| RefSeq | NP_578697.1. NC_003413.1. |
3D structure databases | |
| ProteinModelPortal | Q51802. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBPYRT00000005158; EBPYRP00000005019; EBPYRG00000005157. |
| GeneID | 1468833. |
| GenomeReviews | Gene locus PF0968 in contig AE009950_GR. |
| KEGG | pfu:PF0968. |
| NMPDR | fig|186497.1.peg.1004. |
Phylogenomic databases | |
| GeneTree | EBGT00050000022253. |
| HOGENOM | HBG313203. |
| OMA | HKKKVID. |
| ProtClustDB | PRK11864. |
Family and domain databases | |
| InterPro | IPR011766. TPP_enzyme-bd_C. [Graphical view] |
| KO | K00187. |
| Pfam | PF02775. TPP_enzyme_C. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | VORB_PYRFU | ||||||||
| Accession | Primary (citable) accession number: Q51802 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||

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