Q51517 (PHZC_PSECL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable phospho-2-dehydro-3-deoxyheptonate aldolase
EC=2.5.1.54

Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
DAHP synthase
Phospho-2-keto-3-deoxyheptonate aldolase

Gene names

Name:	phzC
Synonyms:	phzF

Organism

Pseudomonas chlororaphis (Pseudomonas aureofaciens)

Taxonomic identifier

333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate.
Pathway	Antibiotic biosynthesis; phenazine biosynthesis.
Sequence similarities	Belongs to the class-II DAHP synthase family.

Ontologies

Keywords
Biological process	Antibiotic biosynthesis Virulence
Molecular function	Transferase
Gene Ontology (GO)
Biological process	antibiotic biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: InterPro pathogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3-deoxy-7-phosphoheptulonate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 400	400	Probable phospho-2-dehydro-3-deoxyheptonate aldolase		PRO_0000140857

Sequences

	Sequence		Length	Mass (Da)
	Q51517 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 426EC6FF4F399769	FASTA	400	43,942
	10 20 30 40 50 60 MEDLLKRVLS CEAFQQPQWS EPSQLHDAQA YLRDSASLIR VEDILVLRAT LARVAAGEAM 70 80 90 100 110 120 VIQSGDCAED MDESTPDHVA RKAAVLDILA GTFRLVTQQP VVRVGRIAGQ FAKPRSNNNE 130 140 150 160 170 180 RIGDVELPVY RGDMVNGREA VCGHRQHDAQ RLVRGYSAAR DIMQHLGWKA SASQEQLSGS 190 200 210 220 230 240 PAWTNHEMLV LDYELPQLRQ DEQGRVFLGS THWPWIGERT RQLTGAHVTL LSEVLNPVAC 250 260 270 280 290 300 KVGPDITQDQ LLSLCERLDA KREPGRLTLI ARMGAQKVAE RLPPLVEAVR QAGHKIIWLS 310 320 330 340 350 360 DPMHGNTIVA PCGNKTRMVQ AITEEIAAFK HAVTSAGGVA AGLHLETTPD DVSECASDAA 370 380 390 400 GLHQVASRYK SLCDPRLNPW QAITAVMAWK NQPSSTLASF

References

[1]

"Molecular analysis of genes encoding phenazine biosynthesis in the biological control bacterium. Pseudomonas aureofaciens 30-84." Pierson L.S. III, Gaffney T., Lam S., Gong F. FEMS Microbiol. Lett. 134:299-307(1995) [PubMed: 8586283] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 30-84.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L48339 Genomic DNA. Translation: AAB00328.1.
3D structure databases
ProteinModelPortal	Q51517.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR002480. DAHP_synth_2. [Graphical view]
PANTHER	PTHR21337. DAHP_synth_2. 1 hit.
Pfam	PF01474. DAHP_synth_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHZC_PSECL

Accession

Primary (citable) accession number: Q51517

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	September 21, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program