Q51400 (Q51400_PSEAI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Beta-lactamase EMBL AAC46344.1

Gene names

Name:

bla oxa-13 EMBL AAC46344.1

Organism

Pseudomonas aeruginosa EMBL AAC46344.1

Taxonomic identifier

287 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	266 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1H5X PDB 1H8Y PDB 1H8Z
Gene Ontology (GO)
Biological process	antibiotic catabolic process Inferred from electronic annotation. Source: InterPro peptidoglycan-based cell wall biogenesis Inferred from electronic annotation. Source: InterPro
Molecular function	beta-lactamase activity Inferred from electronic annotation. Source: InterPro penicillin binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q51400 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 69A4C4607C8E58C4	FASTA	266	29,364
	10 20 30 40 50 60 MKTFAAYVIT ACLSSTALAS SITENTSWNK EFSAEAVNGV FVLCKSSSKS CATNNLARAS 70 80 90 100 110 120 KEYLPASTFK IPSAIIGLET GVIKNEHQVF KWDGKPRAMK QWERDLSLRG AIQVSAVPVF 130 140 150 160 170 180 QQIAREVGEV RMQKYLKKFS YGNQNISGGI DKFWLEGQLR ISAVNQVEFL ESLFLNKLSA 190 200 210 220 230 240 SKENQLIVKE ALVTEAAPEY LVHSKTGFSG VGTESNPGVA WWVGWVEKGT EVYFFAFNMD 250 260 IDNENKLPLR KSIPTKIMAS EGIIGG

References

[1]	"Carbapenems as inhibitors of OXA-13, a novel, integron-encoded beta-lactamase in Pseudomonas aeruginosa." Mugnier P., Podglajen I., Goldstein F.W., Collatz E. Microbiology 144:1021-1031(1998) [PubMed: 9579076] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: PAe391 EMBL AAC46344.1.
[2]	"Crystal structures of the class D beta-lactamase OXA-13 in the native form and in complex with meropenem." Pernot L., Frenois F., Rybkine T., L'Hermite G., Petrella S., Delettre J., Jarlier V., Collatz E., Sougakoff W. J. Mol. Biol. 310:859-874(2001) [PubMed: 11453693] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 20-266.
[3]	"Crystal Structure of the Acyl-Enzyme Intermediate Oxa-13:Imipenem." Pernot L., Mayer C., Sougakoff W. Submitted (MAY-2001) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 20-266.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U59183 Genomic DNA. Translation: AAC46344.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1H5X	X-ray	1.90	A/B	20-266	[»]
1H8Y	X-ray	2.00	A/B	20-266	[»]
1H8Z	X-ray	1.80	A/B	20-266	[»]

ProteinModelPortal

Q51400.

SMR

Q51400. Positions 20-266.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR012338. Beta-lactam/transpept-like.
IPR002137. Beta-lactam_class-D_AS.
IPR001460. PCN-bd_Tpept.
[Graphical view]

Gene3D

G3DSA:3.40.710.10. G3DSA:3.40.710.10. 1 hit.

Pfam

PF00905. Transpeptidase. 1 hit.
[Graphical view]

SUPFAM

SSF56601. PBP_transp_fold. 1 hit.

PROSITE

PS00337. BETA_LACTAMASE_D. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q51400_PSEAI

Accession

Primary (citable) accession number: Q51400

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	November 16, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)