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Q51162

- Q51162_NEIME

UniProt

Q51162 - Q51162_NEIME

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Protein
Submitted name: Fe-regulated protein B
Gene
frpB
Organism
Neisseria meningitidis
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. receptor activity Source: InterPro
  3. siderophore transmembrane transporter activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Fe-regulated protein BImported
Gene namesi
Name:frpBImported
OrganismiNeisseria meningitidisImported
Taxonomic identifieri487 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Subcellular locationi

Cell outer membrane By similarity UniRule annotation

GO - Cellular componenti

  1. cell outer membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell outer membraneSAAS annotations, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222 PredictedImported
Add
BLAST
Chaini23 – 720698 PredictedImported
PRO_5000146568Add
BLAST

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4AIPX-ray2.40A/B/C23-720[»]
ProteinModelPortaliQ51162.

Family & Domainsi

Sequence similaritiesi

Belongs to the TonB-dependent receptor family.UniRule annotation

Keywords - Domaini

SignalImported, TonB boxUniRule annotationSAAS annotations

Phylogenomic databases

KOiK16087.

Family and domain databases

Gene3Di2.170.130.10. 1 hit.
2.40.170.20. 1 hit.
InterProiIPR017690. OM_insertion_C_omp85_target.
IPR012910. Plug.
IPR000531. TonB-dep_rcpt_b-brl.
IPR010917. TonB_rcpt_CS.
IPR010105. TonB_sidphr_rcpt.
[Graphical view]
PfamiPF07715. Plug. 1 hit.
PF00593. TonB_dep_Rec. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03304. OMP85_target. 2 hits.
TIGR01783. TonB-siderophor. 1 hit.
PROSITEiPS01156. TONB_DEPENDENT_REC_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q51162-1 [UniParc]FASTAAdd to Basket

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MNTPLFRLSL LSLTLAAGFA HAAENNAKVV LDTVTVKGDR QGSKIRTNIV    50
TLQQKDESTA TDMRELLKEE PSIDFGGGNG TSQFLTLRGM GQNSVDIKVD 100
NAYSDSQILY HQGRFIVDPA LVKVVSVQKG AGSASAGIGA TNGAIIAKTV 150
DAQDLLKGLD KNWGVRLNSG FASNEGVSYG ASVFGKEGNF DGLFSYNRND 200
EKDYEAGKGF RNVNGGKTVP YSALDKRSYL AKIGTTFGDD DHRIVLSHMK 250
DQHRGIRTVR EEFTVGDKSS RINIDRQAPA YRETTQSNTN LAYTGKNLGF 300
VEKLDANAYV LEKERYSADD SGTGYAGNVK GPNHTRITTR GANFNFDSRL 350
AEQTLLKYGI NYRHQEIKPQ AFLNSKFSIP TTEEKNGQKV DKPMEQQMKD 400
RADEDTVHAY KLSNPTKTDT GVYVEAIHDI GDFTLTGGLR YDRFKVKTHD 450
GKTVSSSNLN PSFGVIWQPH EHWSFSASHN YASRSPRLYD ALQTHGKRGI 500
ISIADGTKAE RARNTEIGFN YNDGTFAANG SYFWQTIKDA LANPQNRHDS 550
VAVREAVNAG YIKNHGYELG ASYRTGGLTA KVGVSHSKPR FYDTHKDKLL 600
SANPEFGAQV GRTWTASLAY RFQNPNLEIG WRGRYVQKAT GSILAAGQKD 650
RKGNLENVVR KGFGVNDVFA NWKPLGKDTL NVNLSVNNVF NKFYYPHSQR 700
WTNTLPGVGR DVRLGVNYKF 720
Length:720
Mass (Da):79,612
Last modified:November 1, 1996 - v1
Checksum:i7F9E540A12A3DB2D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X89755 Genomic DNA. Translation: CAA61902.1.
PIRiS58133.
RefSeqiYP_005900546.1. NC_017516.1.

Genome annotation databases

GeneIDi12491084.
KEGGinmh:NMBH4476_1926.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X89755 Genomic DNA. Translation: CAA61902.1 .
PIRi S58133.
RefSeqi YP_005900546.1. NC_017516.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4AIP X-ray 2.40 A/B/C 23-720 [» ]
ProteinModelPortali Q51162.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 12491084.
KEGGi nmh:NMBH4476_1926.

Phylogenomic databases

KOi K16087.

Family and domain databases

Gene3Di 2.170.130.10. 1 hit.
2.40.170.20. 1 hit.
InterProi IPR017690. OM_insertion_C_omp85_target.
IPR012910. Plug.
IPR000531. TonB-dep_rcpt_b-brl.
IPR010917. TonB_rcpt_CS.
IPR010105. TonB_sidphr_rcpt.
[Graphical view ]
Pfami PF07715. Plug. 1 hit.
PF00593. TonB_dep_Rec. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03304. OMP85_target. 2 hits.
TIGR01783. TonB-siderophor. 1 hit.
PROSITEi PS01156. TONB_DEPENDENT_REC_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular characterization of FrpB, the 70-kilodalton iron-regulated outer membrane protein of Neisseria meningitidis."
    Pettersson A.M., Maas, van Wassenaar, van der Ley, Tommassen
    Infect. Immun. 63:4181-4184(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H44/76Imported.
  2. "Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis."
    Saleem M., Prince S.M., Rigby S.E., Imran M., Patel H., Chan H., Sanders H., Maiden M.C., Feavers I.M., Derrick J.P.
    PLoS ONE 8:e56746-e56746(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 23-720.

Entry informationi

Entry nameiQ51162_NEIME
AccessioniPrimary (citable) accession number: Q51162
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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