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Q51162

- Q51162_NEIME

UniProt

Q51162 - Q51162_NEIME

Protein
Submitted name:

Fe-regulated protein B

Gene

frpB

Organism
Neisseria meningitidis
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. iron ion binding Source: InterPro
    2. receptor activity Source: InterPro
    3. siderophore transmembrane transporter activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Fe-regulated protein BImported
    Gene namesi
    Name:frpBImported
    OrganismiNeisseria meningitidisImported
    Taxonomic identifieri487 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

    Subcellular locationi

    Cell outer membrane UniRule annotation

    GO - Cellular componenti

    1. cell outer membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell outer membraneSAAS annotation, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222 PotentialImportedAdd
    BLAST
    Chaini23 – 720698 PotentialImportedPRO_5000146568Add
    BLAST

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4AIPX-ray2.40A/B/C23-720[»]
    ProteinModelPortaliQ51162.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TonB-dependent receptor family.UniRule annotation

    Keywords - Domaini

    SignalImported, TonB boxUniRule annotationSAAS annotation

    Phylogenomic databases

    KOiK16087.

    Family and domain databases

    Gene3Di2.170.130.10. 1 hit.
    2.40.170.20. 1 hit.
    InterProiIPR017690. OM_insertion_C_omp85_target.
    IPR012910. Plug.
    IPR000531. TonB-dep_rcpt_b-brl.
    IPR010917. TonB_rcpt_CS.
    IPR010105. TonB_sidphr_rcpt.
    [Graphical view]
    PfamiPF07715. Plug. 1 hit.
    PF00593. TonB_dep_Rec. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03304. OMP85_target. 2 hits.
    TIGR01783. TonB-siderophor. 1 hit.
    PROSITEiPS01156. TONB_DEPENDENT_REC_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q51162-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTPLFRLSL LSLTLAAGFA HAAENNAKVV LDTVTVKGDR QGSKIRTNIV    50
    TLQQKDESTA TDMRELLKEE PSIDFGGGNG TSQFLTLRGM GQNSVDIKVD 100
    NAYSDSQILY HQGRFIVDPA LVKVVSVQKG AGSASAGIGA TNGAIIAKTV 150
    DAQDLLKGLD KNWGVRLNSG FASNEGVSYG ASVFGKEGNF DGLFSYNRND 200
    EKDYEAGKGF RNVNGGKTVP YSALDKRSYL AKIGTTFGDD DHRIVLSHMK 250
    DQHRGIRTVR EEFTVGDKSS RINIDRQAPA YRETTQSNTN LAYTGKNLGF 300
    VEKLDANAYV LEKERYSADD SGTGYAGNVK GPNHTRITTR GANFNFDSRL 350
    AEQTLLKYGI NYRHQEIKPQ AFLNSKFSIP TTEEKNGQKV DKPMEQQMKD 400
    RADEDTVHAY KLSNPTKTDT GVYVEAIHDI GDFTLTGGLR YDRFKVKTHD 450
    GKTVSSSNLN PSFGVIWQPH EHWSFSASHN YASRSPRLYD ALQTHGKRGI 500
    ISIADGTKAE RARNTEIGFN YNDGTFAANG SYFWQTIKDA LANPQNRHDS 550
    VAVREAVNAG YIKNHGYELG ASYRTGGLTA KVGVSHSKPR FYDTHKDKLL 600
    SANPEFGAQV GRTWTASLAY RFQNPNLEIG WRGRYVQKAT GSILAAGQKD 650
    RKGNLENVVR KGFGVNDVFA NWKPLGKDTL NVNLSVNNVF NKFYYPHSQR 700
    WTNTLPGVGR DVRLGVNYKF 720
    Length:720
    Mass (Da):79,612
    Last modified:November 1, 1996 - v1
    Checksum:i7F9E540A12A3DB2D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X89755 Genomic DNA. Translation: CAA61902.1.
    PIRiS58133.
    RefSeqiYP_005900546.1. NC_017516.1.

    Genome annotation databases

    GeneIDi12491084.
    KEGGinmh:NMBH4476_1926.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X89755 Genomic DNA. Translation: CAA61902.1 .
    PIRi S58133.
    RefSeqi YP_005900546.1. NC_017516.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4AIP X-ray 2.40 A/B/C 23-720 [» ]
    ProteinModelPortali Q51162.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 12491084.
    KEGGi nmh:NMBH4476_1926.

    Phylogenomic databases

    KOi K16087.

    Family and domain databases

    Gene3Di 2.170.130.10. 1 hit.
    2.40.170.20. 1 hit.
    InterProi IPR017690. OM_insertion_C_omp85_target.
    IPR012910. Plug.
    IPR000531. TonB-dep_rcpt_b-brl.
    IPR010917. TonB_rcpt_CS.
    IPR010105. TonB_sidphr_rcpt.
    [Graphical view ]
    Pfami PF07715. Plug. 1 hit.
    PF00593. TonB_dep_Rec. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03304. OMP85_target. 2 hits.
    TIGR01783. TonB-siderophor. 1 hit.
    PROSITEi PS01156. TONB_DEPENDENT_REC_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular characterization of FrpB, the 70-kilodalton iron-regulated outer membrane protein of Neisseria meningitidis."
      Pettersson A.M., Maas, van Wassenaar, van der Ley, Tommassen
      Infect. Immun. 63:4181-4184(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: H44/76Imported.
    2. "Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis."
      Saleem M., Prince S.M., Rigby S.E., Imran M., Patel H., Chan H., Sanders H., Maiden M.C., Feavers I.M., Derrick J.P.
      PLoS ONE 8:e56746-e56746(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 23-720.

    Entry informationi

    Entry nameiQ51162_NEIME
    AccessioniPrimary (citable) accession number: Q51162
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3