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Protein

Type-2 restriction enzyme NgoFVII

Gene

ngoFVIIR

Organism
Neisseria gonorrhoeae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Recognizes the double-stranded sequence GCSGC and cleaves after G-4.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processRestriction system

Protein family/group databases

REBASEi3137. NgoFVII.

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme NgoFVII (EC:3.1.21.4)
Short name:
R.NgoFVII
Alternative name(s):
Endonuclease NgoFVII
R.NgoVII
Type II restriction enzyme NgoFVII
Gene namesi
Name:ngoFVIIR
Synonyms:dcrG
OrganismiNeisseria gonorrhoeae
Taxonomic identifieri485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000773461 – 326Type-2 restriction enzyme NgoFVIIAdd BLAST326

Interactioni

Protein-protein interaction databases

STRINGi528357.NgonPI_010100003033.

Structurei

3D structure databases

SMRiQ50976.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiView protein in InterPro
IPR019065. Res_endonuc_III_NgoFVII.
PfamiView protein in Pfam
PF09565. RE_NgoFVII. 1 hit.

Sequencei

Sequence statusi: Complete.

Q50976-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTVFSNIAN AKITEKSLNA VWMDLFKSAD EVLMATGYVS NDAVVELHKI
60 70 80 90 100
LELNDHIQKI DLLVGMHYLE GFSHLQYDSL CKLNDFLRHE KRGAVYVSPF
110 120 130 140 150
VKFHGKMYSF KNYQKINGLI GSANLTCFWD STERTYETML HLNGKPAQIL
160 170 180 190 200
QADIQSTIHK LGKNIQEVER PSKFIEHNSH LENCLGVQKI APEQIRQLFA
210 220 230 240 250
QTSEYHFSIP AKTEEKSNLN VFFGEGRRDK RGFVKPRPWY EVELIVSKDI
260 270 280 290 300
TSQEGYPVLK SFTVITDDGW QFQCKTSGDY SKTSTQKMNL KTLGKWIKGR
310 320
LESHGCLQNN EKITHETLRE YGNESF
Length:326
Mass (Da):37,528
Last modified:November 1, 1996 - v1
Checksum:i1908B94B4DEDFD25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43736 Genomic DNA. Translation: AAA86271.1.
PIRiT10166.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43736 Genomic DNA. Translation: AAA86271.1.
PIRiT10166.

3D structure databases

SMRiQ50976.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi528357.NgonPI_010100003033.

Protein family/group databases

REBASEi3137. NgoFVII.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR019065. Res_endonuc_III_NgoFVII.
PfamiView protein in Pfam
PF09565. RE_NgoFVII. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiT2F7_NEIGO
AccessioniPrimary (citable) accession number: Q50976
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: February 15, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.