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Protein

Type-2 restriction enzyme NgoBV

Gene

ngoBVR

Organism
Neisseria gonorrhoeae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Recognizes the double-stranded sequence GGNNCC and cleaves after N-3.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Restriction system

Protein family/group databases

REBASEi3134. NgoBV.

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme NgoBV (EC:3.1.21.4)
Short name:
R.NgoBV
Alternative name(s):
Endonuclease NgoBV
R.NgoV
Type II restriction enzyme NgoBV
Gene namesi
Name:ngoBVR
Synonyms:dcrE
OrganismiNeisseria gonorrhoeae
Taxonomic identifieri485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000773451 – ›175Type-2 restriction enzyme NgoBVAdd BLAST›175

Structurei

3D structure databases

ProteinModelPortaliQ50975.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR019064. Restrct_endonuc_II_NlaIV.
[Graphical view]
PfamiPF09564. RE_NgoBV. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q50975-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKLTAQQIF DKLLDEEKIL SANGQIRFFL GDVDIIVKQK DVVGNIIQEW
60 70 80 90 100
LGGWLRKREI EFDVSTNTQM PPDFFLNKKD RSRELLEVKA FNRNACPGFD
110 120 130 140 150
IADFKMYSDE SFISPISGCR LFNIGYDMDD NGNVTIKDLW LKKVWQITRS
160 170
MDGWAINFKS KKAWCIKSAR VFGTA
Length:175
Mass (Da):20,257
Last modified:November 1, 1996 - v1
Checksum:i786E8EBCCDF08235
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1751

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43735 Genomic DNA. Translation: AAA86269.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43735 Genomic DNA. Translation: AAA86269.1.

3D structure databases

ProteinModelPortaliQ50975.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

REBASEi3134. NgoBV.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR019064. Restrct_endonuc_II_NlaIV.
[Graphical view]
PfamiPF09564. RE_NgoBV. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiT2B5_NEIGO
AccessioniPrimary (citable) accession number: Q50975
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.