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Protein

Polyferredoxin protein MvhB

Gene

mvhB

Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

[4Fe-4S] clusterCuratedNote: Binds 10 [4Fe-4S] clusters.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi9Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi12Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi15Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi19Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi76Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi79Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi82Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi86Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi107Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi110Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi113Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi117Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi146Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi149Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi152Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi156Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi177Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi180Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi183Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi187Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi216Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi219Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi222Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi226Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi246Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi249Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi252Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi256Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi325Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi328Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi331Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi335Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi366Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi369Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi372Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi376Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi394Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi397Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi400Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi404Iron-sulfur (4Fe-4S)Sequence analysis1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyferredoxin protein MvhB
Gene namesi
Name:mvhB
Ordered Locus Names:MTH_1133
OrganismiMethanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Taxonomic identifieri187420 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter
Proteomesi
  • UP000005223 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001591431 – 412Polyferredoxin protein MvhBAdd BLAST412

Proteomic databases

PRIDEiQ50784.

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH1133.

Structurei

3D structure databases

ProteinModelPortaliQ50784.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 294Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST28
Domaini30 – 574Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST28
Domaini67 – 964Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd BLAST30
Domaini97 – 1274Fe-4S ferredoxin-type 4PROSITE-ProRule annotationAdd BLAST31
Domaini138 – 1664Fe-4S ferredoxin-type 5PROSITE-ProRule annotationAdd BLAST29
Domaini168 – 1974Fe-4S ferredoxin-type 6PROSITE-ProRule annotationAdd BLAST30
Domaini207 – 2364Fe-4S ferredoxin-type 7PROSITE-ProRule annotationAdd BLAST30
Domaini238 – 2664Fe-4S ferredoxin-type 8PROSITE-ProRule annotationAdd BLAST29
Domaini276 – 3054Fe-4S ferredoxin-type 9PROSITE-ProRule annotationAdd BLAST30
Domaini314 – 3454Fe-4S ferredoxin-type 10PROSITE-ProRule annotationAdd BLAST32
Domaini357 – 3864Fe-4S ferredoxin-type 11PROSITE-ProRule annotationAdd BLAST30
Domaini385 – 4124Fe-4S ferredoxin-type 12PROSITE-ProRule annotationAdd BLAST28

Sequence similaritiesi

Contains 12 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG02181. Archaea.
COG1145. LUCA.
OMAiECIGCEK.

Family and domain databases

InterProiIPR001080. 3Fe4S_ferredoxin.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF00037. Fer4. 2 hits.
PF12798. Fer4_3. 1 hit.
PF12800. Fer4_4. 1 hit.
PF12838. Fer4_7. 3 hits.
PF13187. Fer4_9. 1 hit.
[Graphical view]
PRINTSiPR00352. 3FE4SFRDOXIN.
PROSITEiPS00198. 4FE4S_FER_1. 10 hits.
PS51379. 4FE4S_FER_2. 12 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q50784-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIVNKEDCI RCGACQGTCP TAAIEVTPED VIYCDICGGE PKCVDICPTG
60 70 80 90 100
ALKLEDLVVD EAGNTQGRIV FNPDKCNECG DCVEVCPPQI LKLDEGKVKK
110 120 130 140 150
VPLQGFCVMC QKCVDICPVG VIGVEGIKEP AKVELEIEGP IFIADCVGCG
160 170 180 190 200
MCVPECPVDA ITLDKVGGVI EIDEDTCIKC GVCAQTCPWN AVYISGRKPE
210 220 230 240 250
KRAKEIKKFE LDEDACIGCN TCVEACPGDF IVPRTSNLTV ELPAICTACG
260 270 280 290 300
LCEQLCPVDA IDLEVELGPA KPASEEGLVW DEEKCDFIGA CANICPNDAI
310 320 330 340 350
RVVTKEGMKV PDNEKVDEEP SFAMCTRCGA CTVACPKGAL SLVDMDKVVD
360 370 380 390 400
GEVVKRKRVQ YNPALCDQCG DCIEACPYDM LKLTDEKVPL KGFCILCDQC
410
IPACPKGALS LK
Length:412
Mass (Da):44,103
Last modified:January 16, 2004 - v2
Checksum:i845D8F4D55EB3DED
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti96G → A in AAB02352 (PubMed:2654933).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J04540 Genomic DNA. Translation: AAB02352.1.
AE000666 Genomic DNA. Translation: AAB85622.1.
PIRiG30315.
RefSeqiWP_010876757.1. NC_000916.1.

Genome annotation databases

EnsemblBacteriaiAAB85622; AAB85622; MTH_1133.
GeneIDi1471541.
KEGGimth:MTH_1133.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J04540 Genomic DNA. Translation: AAB02352.1.
AE000666 Genomic DNA. Translation: AAB85622.1.
PIRiG30315.
RefSeqiWP_010876757.1. NC_000916.1.

3D structure databases

ProteinModelPortaliQ50784.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187420.MTH1133.

Proteomic databases

PRIDEiQ50784.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB85622; AAB85622; MTH_1133.
GeneIDi1471541.
KEGGimth:MTH_1133.

Phylogenomic databases

eggNOGiarCOG02181. Archaea.
COG1145. LUCA.
OMAiECIGCEK.

Family and domain databases

InterProiIPR001080. 3Fe4S_ferredoxin.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF00037. Fer4. 2 hits.
PF12798. Fer4_3. 1 hit.
PF12800. Fer4_4. 1 hit.
PF12838. Fer4_7. 3 hits.
PF13187. Fer4_9. 1 hit.
[Graphical view]
PRINTSiPR00352. 3FE4SFRDOXIN.
PROSITEiPS00198. 4FE4S_FER_1. 10 hits.
PS51379. 4FE4S_FER_2. 12 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMVHB_METTH
AccessioniPrimary (citable) accession number: Q50784
Secondary accession number(s): O27205
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: January 16, 2004
Last modified: November 2, 2016
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.