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Protein

WSC domain-containing protein 1

Gene

Wscd1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
WSC domain-containing protein 1
Gene namesi
Name:Wscd1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1308212. Wscd1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei15 – 3521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 572572WSC domain-containing protein 1PRO_0000305063Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi105 – 1051N-linked (GlcNAc...)Sequence analysis
Glycosylationi254 – 2541N-linked (GlcNAc...)Sequence analysis
Glycosylationi345 – 3451N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ505J3.
PRIDEiQ505J3.

Expressioni

Gene expression databases

GenevisibleiQ505J3. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010358.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini139 – 23193WSC 1PROSITE-ProRule annotationAdd
BLAST
Domaini242 – 33796WSC 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the WSCD family.Curated
Contains 2 WSC domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4157. Eukaryota.
ENOG4111FP9. LUCA.
GeneTreeiENSGT00390000012250.
HOGENOMiHOG000060082.
HOVERGENiHBG102242.
InParanoidiQ505J3.
OMAiSKEWPDF.
OrthoDBiEOG7QZG95.
PhylomeDBiQ505J3.
TreeFamiTF324060.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR000863. Sulfotransferase_dom.
IPR002889. WSC_carb-bd.
[Graphical view]
PfamiPF00685. Sulfotransfer_1. 1 hit.
PF01822. WSC. 2 hits.
[Graphical view]
SMARTiSM00321. WSC. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51212. WSC. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q505J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKPFFRLQK FLRRTQFLLL FLTAAYLMTG SLLLLQRARV ALPQALRAPG
60 70 80 90 100
SLQALPVATV ALGVGLLDSR SLHDPHSSPD LLLDVDTLRS PLARVPPGIR
110 120 130 140 150
WPRRNRSSLR RRWLHHLTSD PQGPPTLGPE ASGPASHNQG NYLGCFSEEG
160 170 180 190 200
QERTLKGAVF YDLRKMTVSH CQEACAERSY VYAGLEAGAE CYCGNRLPAT
210 220 230 240 250
RVSLKECNQE CKGEKGSMCG ALHRLSVYSV GLQQSGAKKR WTATYRGCFP
260 270 280 290 300
LPENITRTFS SSMTQANVTV ETCSGFCSQK EFPLAILRGW ACYCAYPTPQ
310 320 330 340 350
FSLRDAVDGA LCSQGTEAQG LPGYCEVYQT PVQDTRCTDR KFLPNKSKVF
360 370 380 390 400
VALSSFPGAG NTWARHLIEH ATGFYTGSYY FDGTLYNKGF KGEKDHWRSR
410 420 430 440 450
RTICVKTHES GRREIEMFDS AILLIRNPYR SLVAEFNRKC AGHLGYAPDR
460 470 480 490 500
NWKSKEWPDF VNSYASWWSS HVLDWLKYGK RLLVVHYEEL RHSLVPTLRE
510 520 530 540 550
MVAFLNVSVS EERLLCVENN KEGSFRRRGR HPHDQEPFTP EMKDLINGYI
560 570
RTVDQALRDH NWAGLPREYV PR
Length:572
Mass (Da):64,789
Last modified:June 7, 2005 - v1
Checksum:iC838CB1C31C24634
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC094520 mRNA. Translation: AAH94520.1.
RefSeqiNP_001019405.1. NM_001024234.1.
UniGeneiRn.198297.

Genome annotation databases

EnsembliENSRNOT00000010358; ENSRNOP00000010358; ENSRNOG00000007869.
ENSRNOT00000081954; ENSRNOP00000071155; ENSRNOG00000007869.
GeneIDi287466.
KEGGirno:287466.
UCSCiRGD:1308212. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC094520 mRNA. Translation: AAH94520.1.
RefSeqiNP_001019405.1. NM_001024234.1.
UniGeneiRn.198297.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010358.

Proteomic databases

PaxDbiQ505J3.
PRIDEiQ505J3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000010358; ENSRNOP00000010358; ENSRNOG00000007869.
ENSRNOT00000081954; ENSRNOP00000071155; ENSRNOG00000007869.
GeneIDi287466.
KEGGirno:287466.
UCSCiRGD:1308212. rat.

Organism-specific databases

CTDi23302.
RGDi1308212. Wscd1.

Phylogenomic databases

eggNOGiKOG4157. Eukaryota.
ENOG4111FP9. LUCA.
GeneTreeiENSGT00390000012250.
HOGENOMiHOG000060082.
HOVERGENiHBG102242.
InParanoidiQ505J3.
OMAiSKEWPDF.
OrthoDBiEOG7QZG95.
PhylomeDBiQ505J3.
TreeFamiTF324060.

Miscellaneous databases

NextBioi626236.
PROiQ505J3.

Gene expression databases

GenevisibleiQ505J3. RN.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR000863. Sulfotransferase_dom.
IPR002889. WSC_carb-bd.
[Graphical view]
PfamiPF00685. Sulfotransfer_1. 1 hit.
PF01822. WSC. 2 hits.
[Graphical view]
SMARTiSM00321. WSC. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51212. WSC. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiWSCD1_RAT
AccessioniPrimary (citable) accession number: Q505J3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: June 7, 2005
Last modified: May 11, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.