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Q503W7 (ATD1B_DANRE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATPase family AAA domain-containing protein 1-B

EC=3.6.1.3
Gene names
Name:atad1b
ORF Names:si:bz1g13.1, zgc:110042
OrganismDanio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]
Taxonomic identifier7955 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR). Required for NMDA-stimulated AMPAR internalization in an ATPase-dependent manner By similarity.

Catalytic activity

ATP + H2O = ADP + phosphate.

Subcellular location

Peroxisome By similarity. Cell junctionsynapsepostsynaptic cell membrane By similarity.

Sequence similarities

Belongs to the AAA ATPase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 362362ATPase family AAA domain-containing protein 1-B
PRO_0000084795

Regions

Nucleotide binding137 – 1448ATP Potential

Experimental info

Sequence conflict951H → Y in AAH95151. Ref.2
Sequence conflict2661V → A in AAH95151. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q503W7 [UniParc].

Last modified September 13, 2005. Version 2.
Checksum: 70136A5CC5CF05EC

FASTA36241,094
        10         20         30         40         50         60 
MVLKEIPTEN ITRPLGRNEV IGLLFRLTIF GAVTYFTIKW MVDAIDPTRK QKVEAQKQAE 

        70         80         90        100        110        120 
KLMRQIGVQN VKLSEYEMSI AAHLVDPLTM QITWHDIAGL DEVITELKDT VILPIQKRHL 

       130        140        150        160        170        180 
FEGSRLLQPP KGVLLYGPPG CGKTLIAKAT AKEAGFRFIN LQPSTLTDKW YGESQKLAAA 

       190        200        210        220        230        240 
VFSLAIKLQP SIIFIDEIDS FLRNRSSSDH EATAMMKAQF MSLWDGLDTD YNCQVIIMGA 

       250        260        270        280        290        300 
TNRPQDLDSA ILRRMPTRFH INQPNVRQRK DILKLILENE NVESAVELSE IAKQTDGFSG 

       310        320        330        340        350        360 
SDLREMCRDA ALLCVRDFVH QESPEEDFIR PIRQEDLQRA IEKMKKSKSA GVHEAFMQVP 


LD 

« Hide

References

[1]NIH - Zebrafish Gene Collection (ZGC) project
Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye.
[2]"The zebrafish reference genome sequence and its relationship to the human genome."
Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J. expand/collapse author list , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-281.
Strain: Tuebingen.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC095151 mRNA. Translation: AAH95151.1.
AL731788 Genomic DNA. Translation: CAI11460.1.
RefSeqNP_001019592.1. NM_001024421.2.
UniGeneDr.78224.

3D structure databases

ProteinModelPortalQ503W7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7955.ENSDARP00000073585.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSDART00000079130; ENSDARP00000073585; ENSDARG00000056609.
GeneID368412.
KEGGdre:368412.

Organism-specific databases

CTD368412.
ZFINZDB-GENE-030616-44. atad1b.

Phylogenomic databases

eggNOGCOG0464.
GeneTreeENSGT00550000074823.
HOGENOMHOG000225141.
HOVERGENHBG057074.
OMAREMCRDA.
OrthoDBEOG7SR4MJ.
PhylomeDBQ503W7.
TreeFamTF105016.

Gene expression databases

BgeeQ503W7.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00004. AAA. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00674. AAA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20812908.
PROQ503W7.

Entry information

Entry nameATD1B_DANRE
AccessionPrimary (citable) accession number: Q503W7
Secondary accession number(s): Q5SQM1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: April 16, 2014
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families