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Protein
Submitted name:

Apolipoprotein Ea

Gene

apoea

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processLipid transportSAAS annotation, Transport

Enzyme and pathway databases

ReactomeiR-DRE-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-DRE-8957275 Post-translational protein phosphorylation
R-DRE-8963901 Chylomicron remodeling
R-DRE-8964026 Chylomicron clearance

Names & Taxonomyi

Protein namesi
Submitted name:
Apolipoprotein EaImported
Submitted name:
Zgc:110064Imported
Gene namesi
Name:apoeaImported
Synonyms:zgc:110064Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 19

Organism-specific databases

ZFINiZDB-GENE-010724-18 apoea

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501458659419 – 269Sequence analysisAdd BLAST251

Expressioni

Gene expression databases

BgeeiENSDARG00000102004

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000110656

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili98 – 132Sequence analysisAdd BLAST35
Coiled coili149 – 169Sequence analysisAdd BLAST21
Coiled coili193 – 242Sequence analysisAdd BLAST50

Sequence similaritiesi

Belongs to the apolipoprotein A1/A4/E family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IVK0 Eukaryota
ENOG4111MYC LUCA
GeneTreeiENSGT00730000111315
HOGENOMiHOG000034005
HOVERGENiHBG105614
KOiK04524
OMAiIHAVETK
OrthoDBiEOG091G0KAN
TreeFamiTF334458

Family and domain databases

InterProiView protein in InterPro
IPR000074 ApoA_E
PfamiView protein in Pfam
PF01442 Apolipoprotein, 1 hit

Sequencei

Sequence statusi: Complete.

Q503V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFVAVIVAL AVISGCQGRF LFQDEPRSRW EEAVDQFWNH VSELTTRAEE
60 70 80 90 100
MRDNIKATQL GRELDTLISD SMMELQMYRD DLHSKLAPYA QERAQKFNED
110 120 130 140 150
LQLLVTKLRT HMEEAKDRVT EYTEELRTMV EQNSDELKNK ANSYAKKLRK
160 170 180 190 200
RFNKDIQEIN KKMSTYLEEV QSRASQSVED VKDRLEPYFT SMHERAQQKL
210 220 230 240 250
VNLREALRSQ AEEIKERLDS RMQELRDQVE KTKENVHNTL QQKAEDVQKW
260
FEPYVSHIQK QMEPVWESL
Length:269
Mass (Da):32,035
Last modified:June 7, 2005 - v1
Checksum:i885DEE50F698F679
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU855694 Genomic DNA No translation available.
BC095169 mRNA Translation: AAH95169.1
RefSeqiNP_001018401.1, NM_001020565.1
UniGeneiDr.77157

Genome annotation databases

EnsembliENSDART00000172219; ENSDARP00000133853; ENSDARG00000102004
GeneIDi553587
KEGGidre:553587

Similar proteinsi

Entry informationi

Entry nameiQ503V2_DANRE
AccessioniPrimary (citable) accession number: Q503V2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2005
Last sequence update: June 7, 2005
Last modified: May 23, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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