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Protein
Submitted name:

Nuclear receptor subfamily 2, group C, member 1

Gene

nr2c1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi110 – 185Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 2, group C, member 1Imported
Gene namesi
Name:nr2c1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-041210-198 nr2c1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ503E0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini110 – 185Nuclear receptorInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
HOGENOMiHOG000013058
HOVERGENiHBG008596
KOiK08543

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 2 hits
PROSITEiView protein in PROSITE
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q503E0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGESPRIQL VSADGGLQIV TEQQLAQKVQ IVTAIDQAGA GKQQFILANL
60 70 80 90 100
DYPNQEKLFI KQENSPAKVI LTSSDGSAVN QLLFASPELS GQQIQFVTDG
110 120 130 140 150
SDQGSMKPPV EYCVVCGDKA SGRHYGAVSC EGCKGFFKRS IRKNLVYTCR
160 170 180 190 200
GSGECVINKH HRNRCQYCRL QRCMALGMKQ DSVQCERKPV EVSREKPANC
210 220 230 240 250
APSIEKIYIR KNLCSPLAAM PTFVSQKEST RPTSLLDSNM LLNIQQSISK
260 270 280 290 300
LDNTILIPSS PDQNDSSQGD LGTLANVVTS LGRLNKSREM MDSSTDLSGI
310 320 330 340 350
DTMSNDDSVM TDIQREESND VTRAFDTLTK VLKAEESCGE EVADGAVAVR
360 370 380 390 400
DDEQTSALLE LEGPLLSDMH VPFKLMMPLP MPDFLNLNYI CESASRLLFL
410 420 430 440 450
SMHWARSIPA FQALGSENGI TLMKACWNEL FALGLAQCSH IMNVETILTA
460 470 480 490 500
IINHLQTSLD EEKLSPERVK QVMEHIWRMQ EFCNSMSRMS PDAYEYAYLK
510 520 530 540 550
AVVLFSPDHS AVDGTLQIER FQEKAYMELQ DYVSKVYPED TYRLSKLLVR
560 570 580 590 600
LPALRLMSAA VTEELFFAGL IGNVQIDSII PYILKMESTD YNSQPISGVE
Length:600
Mass (Da):66,709
Last modified:June 7, 2005 - v1
Checksum:i97D67B4AC3567461
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC095365 mRNA Translation: AAH95365.1
RefSeqiNP_001018458.1, NM_001020622.1
UniGeneiDr.42016

Genome annotation databases

GeneIDi553649
KEGGidre:553649

Similar proteinsi

Entry informationi

Entry nameiQ503E0_DANRE
AccessioniPrimary (citable) accession number: Q503E0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2005
Last sequence update: June 7, 2005
Last modified: March 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health