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Protein
Submitted name:

Nuclear receptor subfamily 2, group C, member 1

Gene

nr2c1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotationImported

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 2, group C, member 1Imported
Gene namesi
Name:nr2c1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-041210-198. nr2c1.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ503E0.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000109984.

Structurei

3D structure databases

ProteinModelPortaliQ503E0.
SMRiQ503E0. Positions 113-188.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini110 – 18576Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains 1 Nuclear receptor DNA-binding domain.UniRule annotation
Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOGENOMiHOG000013058.
HOVERGENiHBG008596.
KOiK08543.

Family and domain databases

Gene3Di1.10.565.10. 3 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 2 hits.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q503E0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGESPRIQL VSADGGLQIV TEQQLAQKVQ IVTAIDQAGA GKQQFILANL
60 70 80 90 100
DYPNQEKLFI KQENSPAKVI LTSSDGSAVN QLLFASPELS GQQIQFVTDG
110 120 130 140 150
SDQGSMKPPV EYCVVCGDKA SGRHYGAVSC EGCKGFFKRS IRKNLVYTCR
160 170 180 190 200
GSGECVINKH HRNRCQYCRL QRCMALGMKQ DSVQCERKPV EVSREKPANC
210 220 230 240 250
APSIEKIYIR KNLCSPLAAM PTFVSQKEST RPTSLLDSNM LLNIQQSISK
260 270 280 290 300
LDNTILIPSS PDQNDSSQGD LGTLANVVTS LGRLNKSREM MDSSTDLSGI
310 320 330 340 350
DTMSNDDSVM TDIQREESND VTRAFDTLTK VLKAEESCGE EVADGAVAVR
360 370 380 390 400
DDEQTSALLE LEGPLLSDMH VPFKLMMPLP MPDFLNLNYI CESASRLLFL
410 420 430 440 450
SMHWARSIPA FQALGSENGI TLMKACWNEL FALGLAQCSH IMNVETILTA
460 470 480 490 500
IINHLQTSLD EEKLSPERVK QVMEHIWRMQ EFCNSMSRMS PDAYEYAYLK
510 520 530 540 550
AVVLFSPDHS AVDGTLQIER FQEKAYMELQ DYVSKVYPED TYRLSKLLVR
560 570 580 590 600
LPALRLMSAA VTEELFFAGL IGNVQIDSII PYILKMESTD YNSQPISGVE
Length:600
Mass (Da):66,709
Last modified:June 7, 2005 - v1
Checksum:i97D67B4AC3567461
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC095365 mRNA. Translation: AAH95365.1.
RefSeqiNP_001018458.1. NM_001020622.1.
UniGeneiDr.42016.

Genome annotation databases

GeneIDi553649.
KEGGidre:553649.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC095365 mRNA. Translation: AAH95365.1.
RefSeqiNP_001018458.1. NM_001020622.1.
UniGeneiDr.42016.

3D structure databases

ProteinModelPortaliQ503E0.
SMRiQ503E0. Positions 113-188.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000109984.

Proteomic databases

PaxDbiQ503E0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi553649.
KEGGidre:553649.

Organism-specific databases

CTDi7181.
ZFINiZDB-GENE-041210-198. nr2c1.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOGENOMiHOG000013058.
HOVERGENiHBG008596.
KOiK08543.

Family and domain databases

Gene3Di1.10.565.10. 3 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 2 hits.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ503E0_DANRE
AccessioniPrimary (citable) accession number: Q503E0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 7, 2005
Last sequence update: June 7, 2005
Last modified: September 7, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.