ATP synthase subunit beta - Mycoplasma pneumoniae (strain ATCC 29342 / M129)

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Q50331 (ATPB_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 97. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
ATP synthase subunit beta
EC=3.6.3.14

Alternative name(s):
ATP synthase F1 sector subunit beta
F-ATPase subunit beta

Gene names

Name:	atpD
Ordered Locus Names:	MPN_598
ORF Names:	MP244

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma ›

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits By similarity. HAMAP-Rule MF_01347
Catalytic activity	ATP + H₂O + H⁺(In) = ADP + phosphate + H⁺(Out). HAMAP-Rule MF_01347
Subunit structure	F-type ATPases have 2 components, CF₁ - the catalytic core - and CF₀ - the membrane proton channel. CF₁ has five subunits: alpha₃, beta₃, gamma₁, delta₁, epsilon₁. CF₀ has three main subunits: a₁, b₂ and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF₁ is attached to CF₀ by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_01347.
Sequence similarities	Belongs to the ATPase alpha/beta chains family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP proton-transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 475

475

ATP synthase subunit beta HAMAP-Rule MF_01347

PRO_0000144453

Regions

Nucleotide binding

156 – 163

ATP By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

Q50331 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 1533D5A16D5135AC
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FASTA

475

52,237

        10         20         30         40         50         60 
MKKENITYGK VHQVIGPVVD VIFTESSQLP RIYDCLSVKL AGEELFLEAA QLIGDDIVRC 

        70         80         90        100        110        120 
IALGPTEGLA RNEKVTNYNH PIEVPVGKNV LGRMFNVLGK PIDGKEELPK KPQLPIHRKP 

       130        140        150        160        170        180 
PSFDDQSNTL EIFETGIKVI DLLTPYARGG KIGLFGGAGV GKTVLVQELI HNIAKEHSGL 

       190        200        210        220        230        240 
SVFAGVGERT REGNDLYYEM IQGGVIDKTA LVFGQMNEPP GARMRVALTA LTMAEYFRDH 

       250        260        270        280        290        300 
DNQDVLLFID NIFRFTQAGS EVSALLGRMP SAVGYQPTLA TEMGQLQERI ASTKTGSITS 

       310        320        330        340        350        360 
VQAIYVPADD LTDPAPATTF THLDAKTVLD RNIAALGIFP AINPLESTSR LLDPNIVGIN 

       370        380        390        400        410        420 
HYKVALGVQN ILQRFAELQD IIAILGIDEL ADEDKIIVER ARRIRNFLSQ PFFVAEKFSG 

       430        440        450        460        470 
IAGKYVPLSD TIQSFKEILD GKHDDLPEQA FFFVGTIQEA VEKAKRLKKA TVEEK

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of 56 kb from the genome of the bacterium Mycoplasma pneumoniae comprising the dnaA region, the atp operon and a cluster of ribosomal protein genes." Hilbert H., Himmelreich R., Plagens H., Herrmann R. Nucleic Acids Res. 24:628-639(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 29342 / M129.
[2]	"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U43738 Genomic DNA. Translation: AAC43659.1. U00089 Genomic DNA. Translation: AAB95892.1.
PIR	S62849.
RefSeq	NP_110287.1. NC_000912.1.
3D structure databases
ProteinModelPortal	Q50331.
SMR	Q50331. Positions 9-467.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q50331. 1 interaction.
STRING	272634.MPN598.
Proteomic databases
PaxDb	Q50331.
PRIDE	Q50331.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB95892; AAB95892; MPN_598.
GeneID	877122.
KEGG	mpn:MPN598.
PATRIC	20022677. VBIMycPne110_0661.
Phylogenomic databases
eggNOG	COG0055.
KO	K02112.
OMA	NNIAKGH.
ProtClustDB	PRK09280.
Enzyme and pathway databases
BioCyc	MPNE272634:GJ6Z-644-MONOMER.
Family and domain databases
Gene3D	1.10.1140.10. 1 hit.
HAMAP	MF_01347. ATP_synth_beta_bact.
InterPro	IPR003593. AAA+_ATPase. IPR020003. ATPase_a/bsu_AS. IPR004100. ATPase_a/bsu_N. IPR005722. ATPase_F1-cplx_bsu. IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C. IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd. IPR024034. ATPase_F1_bsu/V1_C. [Graphical view]
PANTHER	PTHR15184:SF8. PTHR15184:SF8. 1 hit.
Pfam	PF00006. ATP-synt_ab. 1 hit. PF00306. ATP-synt_ab_C. 1 hit. PF02874. ATP-synt_ab_N. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF47917. ATPase_a/b_C. 1 hit. SSF50615. ATPase_a/b_N. 1 hit.
TIGRFAMs	TIGR01039. atpD. 1 hit.
PROSITE	PS00152. ATPASE_ALPHA_BETA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPB_MYCPN

Accession

Primary (citable) accession number: Q50331

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 97 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents