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Q50331 (ATPB_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP synthase subunit beta

EC=3.6.3.14
Alternative name(s):
ATP synthase F1 sector subunit beta
F-ATPase subunit beta
Gene names
Name:atpD
Ordered Locus Names:MPN_598
ORF Names:MP244
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length475 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits By similarity. HAMAP-Rule MF_01347

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP-Rule MF_01347

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_01347.

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 475475ATP synthase subunit beta HAMAP-Rule MF_01347
PRO_0000144453

Regions

Nucleotide binding156 – 1638ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q50331 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 1533D5A16D5135AC

FASTA47552,237
        10         20         30         40         50         60 
MKKENITYGK VHQVIGPVVD VIFTESSQLP RIYDCLSVKL AGEELFLEAA QLIGDDIVRC 

        70         80         90        100        110        120 
IALGPTEGLA RNEKVTNYNH PIEVPVGKNV LGRMFNVLGK PIDGKEELPK KPQLPIHRKP 

       130        140        150        160        170        180 
PSFDDQSNTL EIFETGIKVI DLLTPYARGG KIGLFGGAGV GKTVLVQELI HNIAKEHSGL 

       190        200        210        220        230        240 
SVFAGVGERT REGNDLYYEM IQGGVIDKTA LVFGQMNEPP GARMRVALTA LTMAEYFRDH 

       250        260        270        280        290        300 
DNQDVLLFID NIFRFTQAGS EVSALLGRMP SAVGYQPTLA TEMGQLQERI ASTKTGSITS 

       310        320        330        340        350        360 
VQAIYVPADD LTDPAPATTF THLDAKTVLD RNIAALGIFP AINPLESTSR LLDPNIVGIN 

       370        380        390        400        410        420 
HYKVALGVQN ILQRFAELQD IIAILGIDEL ADEDKIIVER ARRIRNFLSQ PFFVAEKFSG 

       430        440        450        460        470 
IAGKYVPLSD TIQSFKEILD GKHDDLPEQA FFFVGTIQEA VEKAKRLKKA TVEEK 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of 56 kb from the genome of the bacterium Mycoplasma pneumoniae comprising the dnaA region, the atp operon and a cluster of ribosomal protein genes."
Hilbert H., Himmelreich R., Plagens H., Herrmann R.
Nucleic Acids Res. 24:628-639(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 29342 / M129.
[2]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U43738 Genomic DNA. Translation: AAC43659.1.
U00089 Genomic DNA. Translation: AAB95892.1.
PIRS62849.
RefSeqNP_110287.1. NC_000912.1.

3D structure databases

ProteinModelPortalQ50331.
SMRQ50331. Positions 9-467.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ50331. 1 interaction.
STRING272634.MPN598.

Proteomic databases

PaxDbQ50331.
PRIDEQ50331.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB95892; AAB95892; MPN_598.
GeneID877122.
KEGGmpn:MPN598.
PATRIC20022677. VBIMycPne110_0661.

Phylogenomic databases

eggNOGCOG0055.
KOK02112.
OMAKYLSQPF.
OrthoDBEOG6HQSP3.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-644-MONOMER.

Family and domain databases

Gene3D1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_01347. ATP_synth_beta_bact.
InterProIPR003593. AAA+_ATPase.
IPR020003. ATPase_a/bsu_AS.
IPR005722. ATPase_F1-cplx_bsu.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR15184:SF8. PTHR15184:SF8. 1 hit.
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF47917. SSF47917. 1 hit.
SSF50615. SSF50615. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR01039. atpD. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATPB_MYCPN
AccessionPrimary (citable) accession number: Q50331
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 14, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names