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Q50331

- ATPB_MYCPN

UniProt

Q50331 - ATPB_MYCPN

Protein

ATP synthase subunit beta

Gene

atpD

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
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    Functioni

    Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.UniRule annotation

    Catalytic activityi

    ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi156 – 1638ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-HAMAP

    GO - Biological processi

    1. ATP hydrolysis coupled proton transport Source: InterPro
    2. plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    ATP synthesis, Hydrogen ion transport, Ion transport, Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMPNE272634:GJ6Z-644-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ATP synthase subunit betaUniRule annotation (EC:3.6.3.14UniRule annotation)
    Alternative name(s):
    ATP synthase F1 sector subunit betaUniRule annotation
    F-ATPase subunit betaUniRule annotation
    Gene namesi
    Name:atpDUniRule annotation
    Ordered Locus Names:MPN_598
    ORF Names:MP244
    OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
    Taxonomic identifieri272634 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000808: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. plasma membrane Source: UniProtKB-SubCell
    2. proton-transporting ATP synthase complex, catalytic core F(1) Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell membrane, CF(1), Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 475475ATP synthase subunit betaPRO_0000144453Add
    BLAST

    Proteomic databases

    PaxDbiQ50331.
    PRIDEiQ50331.

    Interactioni

    Subunit structurei

    F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.UniRule annotation

    Protein-protein interaction databases

    IntActiQ50331. 1 interaction.
    STRINGi272634.MPN598.

    Structurei

    3D structure databases

    ProteinModelPortaliQ50331.
    SMRiQ50331. Positions 9-467.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATPase alpha/beta chains family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0055.
    KOiK02112.
    OMAiKYLSQPF.
    OrthoDBiEOG6HQSP3.

    Family and domain databases

    Gene3Di1.10.1140.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_01347. ATP_synth_beta_bact.
    InterProiIPR003593. AAA+_ATPase.
    IPR020003. ATPase_a/bsu_AS.
    IPR005722. ATPase_F1-cplx_bsu.
    IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
    IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
    IPR004100. ATPase_F1_a/bsu_N.
    IPR024034. ATPase_F1_bsu/V1_C.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR15184:SF8. PTHR15184:SF8. 1 hit.
    PfamiPF00006. ATP-synt_ab. 1 hit.
    PF00306. ATP-synt_ab_C. 1 hit.
    PF02874. ATP-synt_ab_N. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF47917. SSF47917. 1 hit.
    SSF50615. SSF50615. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR01039. atpD. 1 hit.
    PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q50331-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKENITYGK VHQVIGPVVD VIFTESSQLP RIYDCLSVKL AGEELFLEAA    50
    QLIGDDIVRC IALGPTEGLA RNEKVTNYNH PIEVPVGKNV LGRMFNVLGK 100
    PIDGKEELPK KPQLPIHRKP PSFDDQSNTL EIFETGIKVI DLLTPYARGG 150
    KIGLFGGAGV GKTVLVQELI HNIAKEHSGL SVFAGVGERT REGNDLYYEM 200
    IQGGVIDKTA LVFGQMNEPP GARMRVALTA LTMAEYFRDH DNQDVLLFID 250
    NIFRFTQAGS EVSALLGRMP SAVGYQPTLA TEMGQLQERI ASTKTGSITS 300
    VQAIYVPADD LTDPAPATTF THLDAKTVLD RNIAALGIFP AINPLESTSR 350
    LLDPNIVGIN HYKVALGVQN ILQRFAELQD IIAILGIDEL ADEDKIIVER 400
    ARRIRNFLSQ PFFVAEKFSG IAGKYVPLSD TIQSFKEILD GKHDDLPEQA 450
    FFFVGTIQEA VEKAKRLKKA TVEEK 475
    Length:475
    Mass (Da):52,237
    Last modified:November 1, 1997 - v1
    Checksum:i1533D5A16D5135AC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U43738 Genomic DNA. Translation: AAC43659.1.
    U00089 Genomic DNA. Translation: AAB95892.1.
    PIRiS62849.
    RefSeqiNP_110287.1. NC_000912.1.
    WP_010874955.1. NC_000912.1.

    Genome annotation databases

    EnsemblBacteriaiAAB95892; AAB95892; MPN_598.
    GeneIDi877122.
    KEGGimpn:MPN598.
    PATRICi20022677. VBIMycPne110_0661.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U43738 Genomic DNA. Translation: AAC43659.1 .
    U00089 Genomic DNA. Translation: AAB95892.1 .
    PIRi S62849.
    RefSeqi NP_110287.1. NC_000912.1.
    WP_010874955.1. NC_000912.1.

    3D structure databases

    ProteinModelPortali Q50331.
    SMRi Q50331. Positions 9-467.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q50331. 1 interaction.
    STRINGi 272634.MPN598.

    Proteomic databases

    PaxDbi Q50331.
    PRIDEi Q50331.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB95892 ; AAB95892 ; MPN_598 .
    GeneIDi 877122.
    KEGGi mpn:MPN598.
    PATRICi 20022677. VBIMycPne110_0661.

    Phylogenomic databases

    eggNOGi COG0055.
    KOi K02112.
    OMAi KYLSQPF.
    OrthoDBi EOG6HQSP3.

    Enzyme and pathway databases

    BioCyci MPNE272634:GJ6Z-644-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1140.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_01347. ATP_synth_beta_bact.
    InterProi IPR003593. AAA+_ATPase.
    IPR020003. ATPase_a/bsu_AS.
    IPR005722. ATPase_F1-cplx_bsu.
    IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
    IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
    IPR004100. ATPase_F1_a/bsu_N.
    IPR024034. ATPase_F1_bsu/V1_C.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR15184:SF8. PTHR15184:SF8. 1 hit.
    Pfami PF00006. ATP-synt_ab. 1 hit.
    PF00306. ATP-synt_ab_C. 1 hit.
    PF02874. ATP-synt_ab_N. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47917. SSF47917. 1 hit.
    SSF50615. SSF50615. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR01039. atpD. 1 hit.
    PROSITEi PS00152. ATPASE_ALPHA_BETA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of 56 kb from the genome of the bacterium Mycoplasma pneumoniae comprising the dnaA region, the atp operon and a cluster of ribosomal protein genes."
      Hilbert H., Himmelreich R., Plagens H., Herrmann R.
      Nucleic Acids Res. 24:628-639(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 29342 / M129.
    2. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
      Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
      Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29342 / M129.

    Entry informationi

    Entry nameiATPB_MYCPN
    AccessioniPrimary (citable) accession number: Q50331
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 105 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Mycoplasma pneumoniae
      Mycoplasma pneumoniae (strain M129): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3