Q50303 (RL6_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L6

Gene names

Name:	rplF
Ordered Locus Names:	MPN_180
ORF Names:	MP651

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma pneumoniae

Protein attributes

Sequence length	184 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center By similarity. HAMAP-Rule MF_01365
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Sequence similarities	Belongs to the ribosomal protein L6P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 184	184	50S ribosomal protein L6 HAMAP-Rule MF_01365		PRO_0000131061

Sequences

	Sequence		Length	Mass (Da)
	Q50303 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: C92DC101E99C2651	FASTA	184	20,589
	10 20 30 40 50 60 MSKIGNRTIT LDPAKVNLNF QKDHIAVKGP LGQIELKLPP NLPLKFELKD NNLQITRNNE 70 80 90 100 110 120 LKQSKIFHGT YNALITNAII GVTQGFEKKL RLVGVGYRAN VEGETLNLQL GYSHPIKEKI 130 140 150 160 170 180 PKGLTVKVEK NTEITISGIS KELVGQFATE VRKWRKPEPY KGKGVLYFDE VIVRKAGKTA EGKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of 56 kb from the genome of the bacterium Mycoplasma pneumoniae comprising the dnaA region, the atp operon and a cluster of ribosomal protein genes." Hilbert H., Himmelreich R., Plagens H., Herrmann R. Nucleic Acids Res. 24:628-639(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 29342 / M129.
[2]	"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U34795 Genomic DNA. Translation: AAC43701.1. U00089 Genomic DNA. Translation: AAB96299.1.
PIR	S62827.
RefSeq	NP_109868.1. NC_000912.1.
3D structure databases
ProteinModelPortal	Q50303.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q50303. 1 interaction.
STRING	272634.MPN180.
Proteomic databases
PaxDb	Q50303.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB96299; AAB96299; MPN_180.
GeneID	876780.
KEGG	mpn:MPN180.
PATRIC	20021683. VBIMycPne110_0198.
Phylogenomic databases
eggNOG	COG0097.
KO	K02933.
OMA	KRRPEPY.
ProtClustDB	PRK05498.
Enzyme and pathway databases
BioCyc	MPNE272634:GJ6Z-187-MONOMER.
Family and domain databases
Gene3D	3.90.930.12. 2 hits.
HAMAP	MF_01365_B. Ribosomal_L6_B.
InterPro	IPR000702. Ribosomal_L6. IPR020040. Ribosomal_L6_a/b-dom. IPR019906. Ribosomal_L6_bac-type. IPR002358. Ribosomal_L6_CS. [Graphical view]
PANTHER	PTHR11655. PTHR11655. 1 hit. PTHR11655:SF6. PTHR11655:SF6. 1 hit.
Pfam	PF00347. Ribosomal_L6. 2 hits. [Graphical view]
PIRSF	PIRSF002162. Ribosomal_L6. 1 hit.
PRINTS	PR00059. RIBOSOMALL6.
SUPFAM	SSF56053. Ribosomal_L6. 2 hits.
TIGRFAMs	TIGR03654. L6_bact. 1 hit.
PROSITE	PS00525. RIBOSOMAL_L6_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL6_MYCPN

Accession

Primary (citable) accession number: Q50303

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program