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Protein

50S ribosomal protein L6

Gene

rplF

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-187-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L6UniRule annotation
Gene namesi
Name:rplFUniRule annotation
Ordered Locus Names:MPN_180
ORF Names:MP651
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 18418450S ribosomal protein L6PRO_0000131061Add
BLAST

Proteomic databases

PaxDbiQ50303.

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

IntActiQ50303. 1 interaction.
STRINGi272634.MPN180.

Structurei

3D structure databases

ProteinModelPortaliQ50303.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L6P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0097.
KOiK02933.
OMAiCEVSAGR.
OrthoDBiEOG67DPRD.

Family and domain databases

Gene3Di3.90.930.12. 2 hits.
HAMAPiMF_01365_B. Ribosomal_L6_B.
InterProiIPR000702. Ribosomal_L6.
IPR020040. Ribosomal_L6_a/b-dom.
IPR019906. Ribosomal_L6_bac-type.
IPR002358. Ribosomal_L6_CS.
[Graphical view]
PANTHERiPTHR11655. PTHR11655. 1 hit.
PfamiPF00347. Ribosomal_L6. 2 hits.
[Graphical view]
PIRSFiPIRSF002162. Ribosomal_L6. 1 hit.
PRINTSiPR00059. RIBOSOMALL6.
SUPFAMiSSF56053. SSF56053. 2 hits.
TIGRFAMsiTIGR03654. L6_bact. 1 hit.
PROSITEiPS00525. RIBOSOMAL_L6_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q50303-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKIGNRTIT LDPAKVNLNF QKDHIAVKGP LGQIELKLPP NLPLKFELKD
60 70 80 90 100
NNLQITRNNE LKQSKIFHGT YNALITNAII GVTQGFEKKL RLVGVGYRAN
110 120 130 140 150
VEGETLNLQL GYSHPIKEKI PKGLTVKVEK NTEITISGIS KELVGQFATE
160 170 180
VRKWRKPEPY KGKGVLYFDE VIVRKAGKTA EGKK
Length:184
Mass (Da):20,589
Last modified:November 1, 1997 - v1
Checksum:iC92DC101E99C2651
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U34795 Genomic DNA. Translation: AAC43701.1.
U00089 Genomic DNA. Translation: AAB96299.1.
PIRiS62827.
RefSeqiNP_109868.1. NC_000912.1.
WP_010874537.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB96299; AAB96299; MPN_180.
GeneIDi876780.
KEGGimpn:MPN180.
PATRICi20021683. VBIMycPne110_0198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U34795 Genomic DNA. Translation: AAC43701.1.
U00089 Genomic DNA. Translation: AAB96299.1.
PIRiS62827.
RefSeqiNP_109868.1. NC_000912.1.
WP_010874537.1. NC_000912.1.

3D structure databases

ProteinModelPortaliQ50303.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ50303. 1 interaction.
STRINGi272634.MPN180.

Proteomic databases

PaxDbiQ50303.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB96299; AAB96299; MPN_180.
GeneIDi876780.
KEGGimpn:MPN180.
PATRICi20021683. VBIMycPne110_0198.

Phylogenomic databases

eggNOGiCOG0097.
KOiK02933.
OMAiCEVSAGR.
OrthoDBiEOG67DPRD.

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-187-MONOMER.

Family and domain databases

Gene3Di3.90.930.12. 2 hits.
HAMAPiMF_01365_B. Ribosomal_L6_B.
InterProiIPR000702. Ribosomal_L6.
IPR020040. Ribosomal_L6_a/b-dom.
IPR019906. Ribosomal_L6_bac-type.
IPR002358. Ribosomal_L6_CS.
[Graphical view]
PANTHERiPTHR11655. PTHR11655. 1 hit.
PfamiPF00347. Ribosomal_L6. 2 hits.
[Graphical view]
PIRSFiPIRSF002162. Ribosomal_L6. 1 hit.
PRINTSiPR00059. RIBOSOMALL6.
SUPFAMiSSF56053. SSF56053. 2 hits.
TIGRFAMsiTIGR03654. L6_bact. 1 hit.
PROSITEiPS00525. RIBOSOMAL_L6_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of 56 kb from the genome of the bacterium Mycoplasma pneumoniae comprising the dnaA region, the atp operon and a cluster of ribosomal protein genes."
    Hilbert H., Himmelreich R., Plagens H., Herrmann R.
    Nucleic Acids Res. 24:628-639(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 29342 / M129.
  2. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiRL6_MYCPN
AccessioniPrimary (citable) accession number: Q50303
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: January 7, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.