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Q50290

- Y198_MYCPN

UniProt

Q50290 - Y198_MYCPN

Protein

Uncharacterized adenine-specific methylase MPN_198

Gene

MPN_198

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

    GO - Molecular functioni

    1. nucleic acid binding Source: InterPro
    2. site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciMPNE272634:GJ6Z-205-MONOMER.

    Protein family/group databases

    REBASEi6710. M.MpnI.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized adenine-specific methylase MPN_198 (EC:2.1.1.72)
    Alternative name(s):
    M.MpnIP
    Gene namesi
    Ordered Locus Names:MPN_198
    ORF Names:GT9_orf319V, MP633
    OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
    Taxonomic identifieri272634 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000808: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 319319Uncharacterized adenine-specific methylase MPN_198PRO_0000088018Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272634.MPN198.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the N(4)/N(6)-methyltransferase family.Curated

    Phylogenomic databases

    eggNOGiNOG10100.
    KOiK00571.
    OMAiPNNCLWL.
    OrthoDBiEOG60CWHX.

    Family and domain databases

    InterProiIPR002052. DNA_methylase_N6_adenine_CS.
    IPR025247. EcoRI_methylase.
    [Graphical view]
    PfamiPF13651. EcoRI_methylase. 2 hits.
    [Graphical view]
    PROSITEiPS00092. N6_MTASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q50290-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHYFNRAKKA KNNEFYTLFE DIAAEVACYP NAFKGKVVLC NCNDGYQSNF    50
    WQFFQSQFHA LGLKKLVAIA FNPLGNSYQL NFDGKEIKEL PLAGNGSFDS 100
    AEAIVLLKQS DIVVTNPPFS LFQDFVCLLA EHGKQFLVLG HNGAVGYNQI 150
    FKLFKEEQLW YGHTVNSSML FQVQSNFKLY DPKSVNFVKK DGQLFQKVPG 200
    ISWFTNLKKN QQPAWLKTKS RYQGNEHKYP KFDWYDAIFV SKVKEIPLDW 250
    FGYMGVPLTF LNCFNPKQFE LIDCLANPYA TLDTLKTNAY VRSHHGDVRN 300
    VKGKRRYVRV VIKQRQNVI 319
    Length:319
    Mass (Da):36,870
    Last modified:November 1, 1996 - v1
    Checksum:iC665CA40A958A78B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U34795 Genomic DNA. Translation: AAC43683.1.
    U00089 Genomic DNA. Translation: AAB96281.1.
    PIRiS62810.
    RefSeqiNP_109886.1. NC_000912.1.
    WP_010874555.1. NC_000912.1.

    Genome annotation databases

    EnsemblBacteriaiAAB96281; AAB96281; MPN_198.
    GeneIDi876831.
    KEGGimpn:MPN198.
    PATRICi20021719. VBIMycPne110_0216.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U34795 Genomic DNA. Translation: AAC43683.1 .
    U00089 Genomic DNA. Translation: AAB96281.1 .
    PIRi S62810.
    RefSeqi NP_109886.1. NC_000912.1.
    WP_010874555.1. NC_000912.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272634.MPN198.

    Protein family/group databases

    REBASEi 6710. M.MpnI.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB96281 ; AAB96281 ; MPN_198 .
    GeneIDi 876831.
    KEGGi mpn:MPN198.
    PATRICi 20021719. VBIMycPne110_0216.

    Phylogenomic databases

    eggNOGi NOG10100.
    KOi K00571.
    OMAi PNNCLWL.
    OrthoDBi EOG60CWHX.

    Enzyme and pathway databases

    BioCyci MPNE272634:GJ6Z-205-MONOMER.

    Family and domain databases

    InterProi IPR002052. DNA_methylase_N6_adenine_CS.
    IPR025247. EcoRI_methylase.
    [Graphical view ]
    Pfami PF13651. EcoRI_methylase. 2 hits.
    [Graphical view ]
    PROSITEi PS00092. N6_MTASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of 56 kb from the genome of the bacterium Mycoplasma pneumoniae comprising the dnaA region, the atp operon and a cluster of ribosomal protein genes."
      Hilbert H., Himmelreich R., Plagens H., Herrmann R.
      Nucleic Acids Res. 24:628-639(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 29342 / M129.
    2. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
      Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
      Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29342 / M129.

    Entry informationi

    Entry nameiY198_MYCPN
    AccessioniPrimary (citable) accession number: Q50290
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Mycoplasma pneumoniae
      Mycoplasma pneumoniae (strain M129): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3