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Q50287 (T1SF_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative type-1 restriction enzyme specificity protein MPN_201
Alternative name(s):
S.MpnORFFP
Type I restriction enzyme specificity protein MPN_201
Short name=S protein
Gene names
Ordered Locus Names:MPN_201
ORF Names:GT9_orf238, MP630
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity By similarity.

Subunit structure

The type I restriction/modification system is composed of three polypeptides R, M and S By similarity.

Domain

Contains two DNA recognition domains, each specifying recognition of one of the two defined components of the target sequence By similarity.

Sequence similarities

Belongs to the type-I restriction system S methylase family.

Ontologies

Keywords
   Biological processRestriction system
   LigandDNA-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 238238Putative type-1 restriction enzyme specificity protein MPN_201
PRO_0000198050

Sequences

Sequence LengthMass (Da)Tools
Q50287 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 2A5188B9DFC701F5

FASTA23827,550
        10         20         30         40         50         60 
MAEIPIDFPP LKIQEKIATI LDTFTELRAR KKQYAFYRDY LLNQENIRKI YGANIPFETF 

        70         80         90        100        110        120 
QVKDICEIRR GRAITKAYIR NNPGENPVYS AATTNDGELG HIKDCDFDGE YITWTTNGYA 

       130        140        150        160        170        180 
GVVFYRNGKF NASQDCGVLK VKNKKICTKF LSLLLEIEAT KFVHNLASRP KLSQKVMAEI 

       190        200        210        220        230 
ELSFPPLEIQ EKIADILCAF EKLCNDLVEG IPAEIELRKK QLDYYQNFLF NWVQKIRN 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of 56 kb from the genome of the bacterium Mycoplasma pneumoniae comprising the dnaA region, the atp operon and a cluster of ribosomal protein genes."
Hilbert H., Himmelreich R., Plagens H., Herrmann R.
Nucleic Acids Res. 24:628-639(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 29342 / M129.
[2]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U34795 Genomic DNA. Translation: AAC43680.1.
U00089 Genomic DNA. Translation: AAB96278.1.
PIRS62809.

3D structure databases

ProteinModelPortalQ50287.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

REBASE6700. S.MpnORF201P.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96278; AAB96278; MPN_201.
PATRIC20021727. VBIMycPne110_0220.

Phylogenomic databases

eggNOGCOG0732.
OMAFYCTNVC.
OrthoDBEOG6PKF94.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-208-MONOMER.

Family and domain databases

InterProIPR000055. Restrct_endonuc_typeI_HsdS.
[Graphical view]
PfamPF01420. Methylase_S. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameT1SF_MYCPN
AccessionPrimary (citable) accession number: Q50287
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names