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Protein
Submitted name:

CD27 molecule

Gene

Cd27

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-5669034. TNFs bind their physiological receptors.

Names & Taxonomyi

Protein namesi
Submitted name:
CD27 moleculeImported
Submitted name:
Similar to CD27 antigen-mouse, isoform CRA_bImported
Gene namesi
Name:Cd27Imported
Synonyms:MGC112688Imported
ORF Names:rCG_30251Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1560499. Cd27.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei182 – 203HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501109922021 – 251Sequence analysisAdd BLAST231

Expressioni

Gene expression databases

BgeeiENSRNOG00000027466.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000029803.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 104TNFR-CysInterPro annotationAdd BLAST41
Repeati64 – 104TNFR-CysPROSITE-ProRule annotationAdd BLAST41

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IZUP. Eukaryota.
ENOG410ZDEA. LUCA.
GeneTreeiENSGT00510000049297.
HOGENOMiHOG000082545.
HOVERGENiHBG018200.
KOiK05144.
OMAiYSCPREE.
OrthoDBiEOG091G0KN1.
TreeFamiTF336960.

Family and domain databases

CDDicd13408. TNFRSF7. 1 hit.
InterProiView protein in InterPro
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022328. TNFR_7.
IPR034000. TNFRSF7_N.
PfamiView protein in Pfam
PF00020. TNFR_c6. 1 hit.
PRINTSiPR01960. TNFACTORR7.
SMARTiView protein in SMART
SM00208. TNFR. 2 hits.
PROSITEiView protein in PROSITE
PS50050. TNFR_NGFR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q501W2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAWPPLYWLC MLGTLVGLLA TPAPNNCPDR HYWIGAGLCC QMCGPGTFLV
60 70 80 90 100
KHCDQDRAAA QCDPCIPGTS FSPDYHTRPH CESCRHCNSG FLIRNCTVTA
110 120 130 140 150
NAECTCSKGW QCRDQECTEC DPPLNPALTS QPSEAPSPQL PPPTHLPYAT
160 170 180 190 200
EKPSWPPQRQ LPDSTVYSRL PSQRPLCSSD CIRIFVTFSS MLLVFVLGGI
210 220 230 240 250
LFFHQRRNHG PNEDSQAVPE ELCPYSCPRE EEGSVIPIQE DYRKPEPASY

P
Length:251
Mass (Da):27,941
Last modified:June 7, 2005 - v1
Checksum:i99DD5B9BCFCFB2D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07062033 Genomic DNA. No translation available.
BC095844 mRNA. Translation: AAH95844.1.
CH473964 Genomic DNA. Translation: EDM01855.1.
RefSeqiNP_001019506.1. NM_001024335.1.
UniGeneiRn.134200.

Genome annotation databases

EnsembliENSRNOT00000038023; ENSRNOP00000029803; ENSRNOG00000027466.
GeneIDi500318.
KEGGirno:500318.
UCSCiRGD:1560499. rat.

Similar proteinsi

Entry informationi

Entry nameiQ501W2_RAT
AccessioniPrimary (citable) accession number: Q501W2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2005
Last sequence update: June 7, 2005
Last modified: October 25, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported