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Protein
Submitted name:

Prostaglandin-endoperoxide synthase 2

Gene

ptgs2

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-XTR-197264 Nicotinamide salvaging
R-XTR-2142770 Synthesis of 15-eicosatetraenoic acid derivatives
R-XTR-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
R-XTR-9018677 Biosynthesis of DHA-derived SPMs
R-XTR-9018679 Biosynthesis of EPA-derived SPMs
R-XTR-9025094 Biosynthesis of DPAn-3 SPMs
R-XTR-9027604 Biosynthesis of electrophilic Omega-3 PUFA oxo-derivatives

Protein family/group databases

PeroxiBasei4266 XtPGHS02

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin-endoperoxide synthase 2Imported
Submitted name:
Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase)Imported
Gene namesi
Name:ptgs2Imported
Synonyms:MGC97821Imported
ORF Names:TGas066j02.1-001Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-482133 ptgs2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501430947919 – 604Sequence analysisAdd BLAST586

Expressioni

Gene expression databases

BgeeiENSXETG00000017378

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000037831

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 56EGF-likeInterPro annotationAdd BLAST39

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2408 Eukaryota
ENOG410XPZ3 LUCA
GeneTreeiENSGT00390000010743
HOGENOMiHOG000013149
HOVERGENiHBG000366
KOiK11987
OMAiMFAFMAQ
OrthoDBiEOG091G03CD
TreeFamiTF329675

Family and domain databases

Gene3Di1.10.640.10, 1 hit
InterProiView protein in InterPro
IPR029576 COX-2
IPR000742 EGF-like_dom
IPR010255 Haem_peroxidase
IPR019791 Haem_peroxidase_animal
IPR037120 Haem_peroxidase_sf
PANTHERiPTHR11903:SF8 PTHR11903:SF8, 1 hit
PfamiView protein in Pfam
PF03098 An_peroxidase, 1 hit
PRINTSiPR00457 ANPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 1 hit
PS50292 PEROXIDASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q501R2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVLPAAVFL SLLVFSQAAN PCCSNPCQNR GVCMTVGHDR YECDCTRTGF
60 70 80 90 100
YGENCTKPEF LSWLRLKLKP APNTVHYILT HFKGLWNIVN NISFLRDAIM
110 120 130 140 150
RYVLTSRSHL IDSPPTYNSH YGYKSWEAFS NLSYYTRTLP PVERDCPTPM
160 170 180 190 200
GVKGMKELPS AKLVVEKFLM RRKFIPDPQG SNVMFAFFAQ HFTHQFFRTD
210 220 230 240 250
MAKGAAFTKA LGHGVDLNHI YGESLERQHK LRLMKGGKLK YQMISGEMYP
260 270 280 290 300
PTVKTTGVDM VYPPHIPDHL QFAVGQEVFG LVPGLMMYST IWLREHNRVC
310 320 330 340 350
DILSNEHPEW DDERIFQTAR LILIGETIKI VIEDYVQHLS GYHFKLKFDP
360 370 380 390 400
ELLFNQKFQY QNRISAEFNT LYHWHPLLPD TFAISEKEYS YPQFLYNNSV
410 420 430 440 450
MLNHGLTEMV ESFSRQTAGR VAGGRNFPAA ITRVAVASIE HSREMRYQSL
460 470 480 490 500
NEYRKRFMLK PFESFEELTG EKEMSAELEK LYGDIDAMEF YPGLLVEQPR
510 520 530 540 550
PGAIFGETMV EIGAPFSLKG LMGNPICSPE YWKPSTFGGS VGFDIVNSAS
560 570 580 590 600
LQKLICNNVR DCPYTAFHVL KSKPSEKDFI NASSDSTLEN VKPSLILKEH

ASEL
Length:604
Mass (Da):69,100
Last modified:June 7, 2005 - v1
Checksum:i6333B374EA926B0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01026272 Genomic DNA No translation available.
BC095912 mRNA Translation: AAH95912.1
CR942339 mRNA Translation: CAJ83938.1
RefSeqiNP_001025697.1, NM_001030526.1
UniGeneiStr.15770

Genome annotation databases

EnsembliENSXETT00000037831; ENSXETP00000037831; ENSXETG00000017378
GeneIDi595089
KEGGixtr:595089

Similar proteinsi

Entry informationi

Entry nameiQ501R2_XENTR
AccessioniPrimary (citable) accession number: Q501R2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2005
Last sequence update: June 7, 2005
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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