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Q501F9

- P2C67_ARATH

UniProt

Q501F9 - P2C67_ARATH

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Protein

Probable protein phosphatase 2C 67

Gene

At5g02760

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi77 – 771Manganese 1By similarity
Metal bindingi77 – 771Manganese 2By similarity
Metal bindingi78 – 781Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi276 – 2761Manganese 2By similarity
Metal bindingi335 – 3351Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT5G02760-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 67 (EC:3.1.3.16)
Short name:
AtPP2C67
Gene namesi
Ordered Locus Names:At5g02760
ORF Names:F9G14.70
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G02760.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 370370Probable protein phosphatase 2C 67PRO_0000367988Add
BLAST

Proteomic databases

PaxDbiQ501F9.
PRIDEiQ501F9.

Expressioni

Gene expression databases

GenevestigatoriQ501F9.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G02760.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ501F9.
SMRiQ501F9. Positions 44-349.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini72 – 316245PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000238703.
InParanoidiQ501F9.
OMAiMVKPCWR.
PhylomeDBiQ501F9.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q501F9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKPCWRIGA GMERSKINPT KVDGLTWYKD LGLHTFGEFS MAMIQANSVM
60 70 80 90 100
EDQCQIESGP LTFNNPTVQG TFVGVYDGHG GPEASRFIAD NIFPKLKKFA
110 120 130 140 150
SEGREISEQV ISKAFAETDK DFLKTVTKQW PTNPQMASVG SCCLAGVICN
160 170 180 190 200
GLVYIANTGD SRAVLGRSER GGVRAVQLSV EHNANLESAR QELWSLHPND
210 220 230 240 250
PTILVMKHRL WRVKGVIQVT RSIGDAYLKR AEFNREPLLP KFRLPEHFTK
260 270 280 290 300
PILSADPSVT ITRLSPQDEF IILASDGLWE HLSNQEAVDI VHNSPRQGIA
310 320 330 340 350
RRLLKAALKE AAKKREMRYS DLTEIHPGVR RHFHDDITVI VVYLNPHPVK
360 370
TNSWASPLSI RGGYPMHSTS
Length:370
Mass (Da):41,334
Last modified:June 7, 2005 - v1
Checksum:i9F21EC0115FD62FD
GO

Sequence cautioni

The sequence CAB86030.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162973 Genomic DNA. Translation: CAB86030.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED90514.1.
BT022008 mRNA. Translation: AAY25420.1.
BT023482 mRNA. Translation: AAY57321.1.
PIRiT48297.
RefSeqiNP_195896.2. NM_120354.3.
UniGeneiAt.23648.
At.69718.

Genome annotation databases

EnsemblPlantsiAT5G02760.1; AT5G02760.1; AT5G02760.
GeneIDi831234.
KEGGiath:AT5G02760.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162973 Genomic DNA. Translation: CAB86030.1 . Sequence problems.
CP002688 Genomic DNA. Translation: AED90514.1 .
BT022008 mRNA. Translation: AAY25420.1 .
BT023482 mRNA. Translation: AAY57321.1 .
PIRi T48297.
RefSeqi NP_195896.2. NM_120354.3.
UniGenei At.23648.
At.69718.

3D structure databases

ProteinModelPortali Q501F9.
SMRi Q501F9. Positions 44-349.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT5G02760.1-P.

Proteomic databases

PaxDbi Q501F9.
PRIDEi Q501F9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G02760.1 ; AT5G02760.1 ; AT5G02760 .
GeneIDi 831234.
KEGGi ath:AT5G02760.

Organism-specific databases

TAIRi AT5G02760.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000238703.
InParanoidi Q501F9.
OMAi MVKPCWR.
PhylomeDBi Q501F9.

Enzyme and pathway databases

BioCyci ARA:AT5G02760-MONOMER.

Gene expression databases

Genevestigatori Q501F9.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
    Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
    , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
    Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Arabidopsis ORF clones."
    Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.
    Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C67_ARATH
AccessioniPrimary (citable) accession number: Q501F9
Secondary accession number(s): Q9LZ09
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 7, 2005
Last modified: November 26, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3