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Q501F9

- P2C67_ARATH

UniProt

Q501F9 - P2C67_ARATH

Protein

Probable protein phosphatase 2C 67

Gene

At5g02760

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (07 Jun 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi77 – 771Manganese 1By similarity
    Metal bindingi77 – 771Manganese 2By similarity
    Metal bindingi78 – 781Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi276 – 2761Manganese 2By similarity
    Metal bindingi335 – 3351Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G02760-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 67 (EC:3.1.3.16)
    Short name:
    AtPP2C67
    Gene namesi
    Ordered Locus Names:At5g02760
    ORF Names:F9G14.70
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G02760.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 370370Probable protein phosphatase 2C 67PRO_0000367988Add
    BLAST

    Proteomic databases

    PaxDbiQ501F9.
    PRIDEiQ501F9.

    Expressioni

    Gene expression databases

    GenevestigatoriQ501F9.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT5G02760.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ501F9.
    SMRiQ501F9. Positions 44-349.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini72 – 316245PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000238703.
    InParanoidiQ501F9.
    OMAiMVKPCWR.
    PhylomeDBiQ501F9.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q501F9-1 [UniParc]FASTAAdd to Basket

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    MVKPCWRIGA GMERSKINPT KVDGLTWYKD LGLHTFGEFS MAMIQANSVM    50
    EDQCQIESGP LTFNNPTVQG TFVGVYDGHG GPEASRFIAD NIFPKLKKFA 100
    SEGREISEQV ISKAFAETDK DFLKTVTKQW PTNPQMASVG SCCLAGVICN 150
    GLVYIANTGD SRAVLGRSER GGVRAVQLSV EHNANLESAR QELWSLHPND 200
    PTILVMKHRL WRVKGVIQVT RSIGDAYLKR AEFNREPLLP KFRLPEHFTK 250
    PILSADPSVT ITRLSPQDEF IILASDGLWE HLSNQEAVDI VHNSPRQGIA 300
    RRLLKAALKE AAKKREMRYS DLTEIHPGVR RHFHDDITVI VVYLNPHPVK 350
    TNSWASPLSI RGGYPMHSTS 370
    Length:370
    Mass (Da):41,334
    Last modified:June 7, 2005 - v1
    Checksum:i9F21EC0115FD62FD
    GO

    Sequence cautioni

    The sequence CAB86030.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL162973 Genomic DNA. Translation: CAB86030.1. Sequence problems.
    CP002688 Genomic DNA. Translation: AED90514.1.
    BT022008 mRNA. Translation: AAY25420.1.
    BT023482 mRNA. Translation: AAY57321.1.
    PIRiT48297.
    RefSeqiNP_195896.2. NM_120354.3.
    UniGeneiAt.23648.
    At.69718.

    Genome annotation databases

    EnsemblPlantsiAT5G02760.1; AT5G02760.1; AT5G02760.
    GeneIDi831234.
    KEGGiath:AT5G02760.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL162973 Genomic DNA. Translation: CAB86030.1 . Sequence problems.
    CP002688 Genomic DNA. Translation: AED90514.1 .
    BT022008 mRNA. Translation: AAY25420.1 .
    BT023482 mRNA. Translation: AAY57321.1 .
    PIRi T48297.
    RefSeqi NP_195896.2. NM_120354.3.
    UniGenei At.23648.
    At.69718.

    3D structure databases

    ProteinModelPortali Q501F9.
    SMRi Q501F9. Positions 44-349.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT5G02760.1-P.

    Proteomic databases

    PaxDbi Q501F9.
    PRIDEi Q501F9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G02760.1 ; AT5G02760.1 ; AT5G02760 .
    GeneIDi 831234.
    KEGGi ath:AT5G02760.

    Organism-specific databases

    TAIRi AT5G02760.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000238703.
    InParanoidi Q501F9.
    OMAi MVKPCWR.
    PhylomeDBi Q501F9.

    Enzyme and pathway databases

    BioCyci ARA:AT5G02760-MONOMER.

    Gene expression databases

    Genevestigatori Q501F9.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
      Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
      , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
      Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Arabidopsis ORF clones."
      Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.
      Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C67_ARATH
    AccessioniPrimary (citable) accession number: Q501F9
    Secondary accession number(s): Q9LZ09
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: June 7, 2005
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3