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Q4ZZF5 (SYR_PSEU2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Psyr_0397
OrganismPseudomonas syringae pv. syringae (strain B728a) [Complete proteome] [HAMAP]
Taxonomic identifier205918 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonasPseudomonas syringae

Protein attributes

Sequence length579 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 579579Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242072

Regions

Motif128 – 13811"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q4ZZF5 [UniParc].

Last modified June 7, 2005. Version 1.
Checksum: 7643E2AAA0D164E9

FASTA57963,675
        10         20         30         40         50         60 
MKDTIRQLIQ QALTRLVTEG VLPEGLTPAI QVENARDKTH GDFASNIAMM LAKPAGMKPR 

        70         80         90        100        110        120 
DLAEKLIAAL PADQQISKVE IAGPGFLNFF QNTAALAARL DAALADPEKL SVRKAGAAQR 

       130        140        150        160        170        180 
VVVDLSAPNL AKEMHVGHLR STIIGDGVAN VLEFLGDTVI RQNHVGDWGT QFGMLLAYLQ 

       190        200        210        220        230        240 
EKPATSDELS DLENFYRAAK QRFDESEEFA ERARGLVVKL QAGDAECLAL WTRFKDISLS 

       250        260        270        280        290        300 
HCQETYERLN VKLTPADVMG ESAYNDDLAN VVNDLKATGL LVESNGAQCV FLEEFRTADD 

       310        320        330        340        350        360 
TPLPVIVQKA GGGYLYATTD LAAIRYRSKV LKADRVLYFV DQRQALHFQQ VFEVARRAGF 

       370        380        390        400        410        420 
VHDGMQLEHM GFGTMNGADG RPFKTRDGGT VKLIDLLDEA EERAYTLVRE KNPEVAEAEL 

       430        440        450        460        470        480 
RSIAKAVGIS AVKYADLSKH RASDYSFNFD QMLSFEGNTA PYLLYAYTRV AGVFRKLGSA 

       490        500        510        520        530        540 
FDASKGQIVL AAPQEQELAA RLAQFTETLN NVAEKGTPHV LCAYLYDLAG LFSSFYENCP 

       550        560        570 
ILGAENPDQQ QSRLRLAALT GRTLKQGLDL LGLETLERM 

« Hide

References

[1]"Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000."
Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A., Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S., Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M., Kyrpides N.C., Ivanova N., Lindow S.E.
Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B728a.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000075 Genomic DNA. Translation: AAY35467.1.
RefSeqYP_233505.1. NC_007005.1.

3D structure databases

ProteinModelPortalQ4ZZF5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING205918.Psyr_0397.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY35467; AAY35467; Psyr_0397.
GeneID3365873.
KEGGpsb:Psyr_0397.
PATRIC19981211. VBIPseSyr42314_0411.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMADIMAESA.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycPSYR205918:GJ94-398-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PSEU2
AccessionPrimary (citable) accession number: Q4ZZF5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 7, 2005
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries