Q4ZYV7 (PNCB_PSEU2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase
Short name=NAPRTase
EC=2.4.2.11

Gene names

Name:	pncB
Ordered Locus Names:	Psyr_0595

Organism

Pseudomonas syringae pv. syringae (strain B728a) [Complete proteome] [HAMAP]

Taxonomic identifier

205918 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas syringae

Protein attributes

Sequence length	407 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570
Subcellular location	Cytoplasm By similarity HAMAP MF_00570.
Sequence similarities	Belongs to the NAPRTase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: EC nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 407	407	Nicotinate phosphoribosyltransferase HAMAP MF_00570		PRO_1000025008

Sequences

	Sequence		Length	Mass (Da)
	Q4ZYV7 [UniParc]. Last modified June 7, 2005. Version 1. Checksum: 721ACA2AF017D55C	FASTA	407	46,678
	10 20 30 40 50 60 MSESAFSNRI VQSLLDTDFY KLTMMQAVLH NYPNVDVEWE FRCRNGEDLR PYLDEIKHQI 70 80 90 100 110 120 ELLCELSLSP EHLAFLERIT FIKPDFLRFL GLFRFNTRYV KTTIENDELC IRLHGPWLHV 130 140 150 160 170 180 ILFEVPLLAI VSEVRNRHRY PDTLLSQARD RLYDKFEWLT THATTDELAE LKVADFGTRR 190 200 210 220 230 240 RFSYRVQEEM LGVLKNDFPG QFVGTSNVHL ARQLDLKPLG TMAHEWIMAH QQLGPRLIDS 250 260 270 280 290 300 QIAALDCWVR EYRGLLGIAL TDCITTDAFL NDFDLYFAKL FDGLRHDSGD PVKWAEKCIS 310 320 330 340 350 360 HYQKLGIDPM SKTLVFSDGL NLPKALDIFR ALRGRINVSF GIGTNLTADI PGIAPMNMVL 370 380 390 400 KMTACAGQAV AKISDEPGKT QCKDPNFVAY LRHVFKVPDL PSPEKPA

References

[1]

"Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000." Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A., Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S., Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M., Kyrpides N.C., Ivanova N., Lindow S.E. Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005) [PubMed: 16043691] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B728a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000075 Genomic DNA. Translation: AAY35665.1.
RefSeq	YP_233703.1. NC_007005.1.
3D structure databases
HSSP	HSSP built from PDB template 1VLP based on UniProtKB P39683.
ProteinModelPortal	Q4ZYV7.
SMR	Q4ZYV7. Positions 1-397.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4ZYV7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3366073.
GenomeReviews	Gene locus Psyr_0595 in contig CP000075_GR.
KEGG	psb:Psyr_0595.
NMPDR	fig|205918.4.peg.928.
PATRIC	19981629. VBIPseSyr42314_0618.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1488.
HOGENOM	HBG325503.
OMA	HQFPQTH.
PhylomeDB	Q4ZYV7.
ProtClustDB	PRK05321.
Enzyme and pathway databases
BioCyc	PSYR205918:PSYR_0595-MONOMER.
Family and domain databases
HAMAP	MF_00570. NAPRTase. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
KO	K00763.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PNCB_PSEU2

Accession

Primary (citable) accession number: Q4ZYV7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 7, 2005
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program