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Q4ZYV7

- PNCB_PSEU2

UniProt

Q4ZYV7 - PNCB_PSEU2

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, Psyr_0595
Organism
Pseudomonas syringae pv. syringae (strain B728a)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciPSYR205918:GJ94-598-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:Psyr_0595
OrganismiPseudomonas syringae pv. syringae (strain B728a)
Taxonomic identifieri205918 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonasPseudomonas syringae
ProteomesiUP000000426: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 407407Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_1000025008Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi205918.Psyr_0595.

Structurei

3D structure databases

ProteinModelPortaliQ4ZYV7.
SMRiQ4ZYV7. Positions 1-397.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4ZYV7-1 [UniParc]FASTAAdd to Basket

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MSESAFSNRI VQSLLDTDFY KLTMMQAVLH NYPNVDVEWE FRCRNGEDLR    50
PYLDEIKHQI ELLCELSLSP EHLAFLERIT FIKPDFLRFL GLFRFNTRYV 100
KTTIENDELC IRLHGPWLHV ILFEVPLLAI VSEVRNRHRY PDTLLSQARD 150
RLYDKFEWLT THATTDELAE LKVADFGTRR RFSYRVQEEM LGVLKNDFPG 200
QFVGTSNVHL ARQLDLKPLG TMAHEWIMAH QQLGPRLIDS QIAALDCWVR 250
EYRGLLGIAL TDCITTDAFL NDFDLYFAKL FDGLRHDSGD PVKWAEKCIS 300
HYQKLGIDPM SKTLVFSDGL NLPKALDIFR ALRGRINVSF GIGTNLTADI 350
PGIAPMNMVL KMTACAGQAV AKISDEPGKT QCKDPNFVAY LRHVFKVPDL 400
PSPEKPA 407
Length:407
Mass (Da):46,678
Last modified:June 7, 2005 - v1
Checksum:i721ACA2AF017D55C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000075 Genomic DNA. Translation: AAY35665.1.
RefSeqiWP_010427809.1. NC_007005.1.
YP_233703.1. NC_007005.1.

Genome annotation databases

EnsemblBacteriaiAAY35665; AAY35665; Psyr_0595.
GeneIDi3366073.
KEGGipsb:Psyr_0595.
PATRICi19981629. VBIPseSyr42314_0618.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000075 Genomic DNA. Translation: AAY35665.1 .
RefSeqi WP_010427809.1. NC_007005.1.
YP_233703.1. NC_007005.1.

3D structure databases

ProteinModelPortali Q4ZYV7.
SMRi Q4ZYV7. Positions 1-397.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 205918.Psyr_0595.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAY35665 ; AAY35665 ; Psyr_0595 .
GeneIDi 3366073.
KEGGi psb:Psyr_0595.
PATRICi 19981629. VBIPseSyr42314_0618.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci PSYR205918:GJ94-598-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B728a.

Entry informationi

Entry nameiPNCB_PSEU2
AccessioniPrimary (citable) accession number: Q4ZYV7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 7, 2005
Last modified: September 3, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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