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Protein

Chemotaxis response regulator protein-glutamate methylesterase 1

Gene

cheB1

Organism
Pseudomonas syringae pv. syringae (strain B728a)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR.UniRule annotation

Catalytic activityi

Protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei182UniRule annotation1
Active sitei208UniRule annotation1
Active sitei304UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processChemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis response regulator protein-glutamate methylesterase 1UniRule annotation (EC:3.1.1.61UniRule annotation)
Gene namesi
Name:cheB1UniRule annotation
Ordered Locus Names:Psyr_0781
OrganismiPseudomonas syringae pv. syringae (strain B728a)
Taxonomic identifieri205918 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonasPseudomonas syringae
Proteomesi
  • UP000000426 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002254761 – 358Chemotaxis response regulator protein-glutamate methylesterase 1Add BLAST358

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei584-aspartylphosphateUniRule annotation1

Post-translational modificationi

Phosphorylated by CheA. Phosphorylation suppresses the inhibitory activity of the N-terminal domain.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi205918.Psyr_0781.

Structurei

3D structure databases

ProteinModelPortaliQ4ZYD3.
SMRiQ4ZYD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 124Response regulatoryPROSITE-ProRule annotationAdd BLAST118
Domaini170 – 358CheB-type methylesteraseUniRule annotationAdd BLAST189

Domaini

The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMP. Bacteria.
COG2201. LUCA.
HOGENOMiHOG000151423.
KOiK03412.
OMAiHAMAQTT.
OrthoDBiPOG091H045J.

Family and domain databases

CDDicd16432. CheB_Rec. 1 hit.
cd00156. REC. 1 hit.
Gene3Di3.40.50.180. 1 hit.
HAMAPiMF_00099. CheB_methylest. 1 hit.
InterProiView protein in InterPro
IPR035909. CheB_C.
IPR011006. CheY-like_superfamily.
IPR008248. Sig_transdc_resp-reg_CheB.
IPR000673. Sig_transdc_resp-reg_Me-estase.
IPR001789. Sig_transdc_resp-reg_receiver.
PfamiView protein in Pfam
PF01339. CheB_methylest. 1 hit.
PF00072. Response_reg. 1 hit.
PIRSFiPIRSF000876. RR_chemtxs_CheB. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF52738. SSF52738. 1 hit.
PROSITEiView protein in PROSITE
PS50122. CHEB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4ZYD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNKKISVLL VDDSAVVRQV LVAILNDTPD IHVMGAASDP IFAMSKLAQE
60 70 80 90 100
WPDVIVLDVE MPRMDGITFL KKIMSERPTP VVICSSLTQK GAETSLQALS
110 120 130 140 150
AGAVEIITKP TTGLKNFLID SAAELVAAVR AAANSNVRNL GKRTAAPVLN
160 170 180 190 200
PASKLTADAI LPAASGHAMA QTTERIVAIG TSTGGTQALE AVLTALPRVC
210 220 230 240 250
PGMVIVQHMP EKFTASFAER LNSLSQIEVR EARNNDRILP GLALIAPGGK
260 270 280 290 300
HMMVTRSGAY YHVQVIDGPL VNRHRPSVDV LFRSVAKFAG KNATGIIMTG
310 320 330 340 350
MGDDGARGLK EMLDAGSATV AQDEASCVVF GMPKEAIKLN AAQRIIPLQE

IHQAILHR
Length:358
Mass (Da):37,997
Last modified:June 7, 2005 - v1
Checksum:i1DFDE66425F31A93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000075 Genomic DNA. Translation: AAY35839.1.
RefSeqiWP_011266626.1. NC_007005.1.
YP_233877.1. NC_007005.1.

Genome annotation databases

EnsemblBacteriaiAAY35839; AAY35839; Psyr_0781.
GeneIDi3366268.
KEGGipsb:Psyr_0781.
PATRICifig|205918.7.peg.807.

Similar proteinsi

Entry informationi

Entry nameiCHEB1_PSEU2
AccessioniPrimary (citable) accession number: Q4ZYD3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: June 7, 2005
Last modified: November 22, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome