Q4ZXL0 (ALGL_PSEU2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Alginate lyase
EC=4.2.2.3

Alternative name(s):
Poly(beta-D-mannuronate) lyase
Poly(mana) alginate lyase

Gene names

Name:	algL
Ordered Locus Names:	Psyr_1056

Organism

Pseudomonas syringae pv. syringae (strain B728a) [Complete proteome] [HAMAP]

Taxonomic identifier

205918 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas syringae

Protein attributes

Sequence length	378 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond By similarity. HAMAP MF_00557
Catalytic activity	Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. HAMAP MF_00557
Subcellular location	Periplasm Potential HAMAP MF_00557.
Sequence similarities	Belongs to the polysaccharide lyase 5 family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alginic acid catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	poly(beta-D-mannuronate) lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential
	Chain	29 – 378	350	Alginate lyase HAMAP MF_00557		PRO_5000000624

Sequences

	Sequence		Length	Mass (Da)
	Q4ZXL0 [UniParc]. Last modified June 7, 2005. Version 1. Checksum: 9E7F9120396267F2	FASTA	378	42,439
	10 20 30 40 50 60 MQTPKLIRPT LLSMAILSSM AWATGASAAL VPPKGYDAPI EKIKTGDHSF SCEAIPKPYT 70 80 90 100 110 120 DKLVFRSKYE GSDKARATLN AVSEEAFRDA TKDITTLERG VSKVVMQYMR DGRPEQLDCA 130 140 150 160 170 180 LNMMTTWAKA DALESREFNH TGKSMRKWAL GSMSSAYLRL KFSESHPLAN RQQDAKIIEA 190 200 210 220 230 240 WFSKLADQVV SDWSNLPLDK INNHSYWAAW SVMATAVATN RQDLFDWAVK EYKVAANQVD 250 260 270 280 290 300 KDGFLPNEMK RRQRALSYHN YALPPLAMIA SFAQANGVDL RPENNGALKR LGDRVLAGVK 310 320 330 340 350 360 DPSIFAEHNG EKQDMTDLKK DPKFAWLEPY CSLYTCSPDV LEEKHEKQPF KTFRLGGDLT 370 KVYDPSHEKG DKGDNDGS

References

[1]

"Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000." Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A., Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S., Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M., Kyrpides N.C., Ivanova N., Lindow S.E. Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005) [PubMed: 16043691] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B728a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000075 Genomic DNA. Translation: AAY36112.1.
RefSeq	YP_234150.1. NC_007005.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q4ZXL0.
Protein family/group databases
CAZy	PL5. Polysaccharide Lyase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3366550.
GenomeReviews	Gene locus Psyr_1056 in contig CP000075_GR.
KEGG	psb:Psyr_1056.
NMPDR	fig|205918.4.peg.1375.
PATRIC	19982595. VBIPseSyr42314_1086.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG42597.
HOGENOM	HBG336064.
OMA	AAWSVMA.
ProtClustDB	PRK00325.
Enzyme and pathway databases
BioCyc	PSYR205918:PSYR_1056-MONOMER.
Family and domain databases
HAMAP	MF_00557. Alginate_lyase. [Tree]
InterPro	IPR022859. Alginate_lyase. IPR008397. Alginate_lyase_dom. IPR008929. Chondroitin_lyas. [Graphical view]
Gene3D	G3DSA:1.50.10.110. Alginate_lyase. 1 hit.
KO	K01729.
Pfam	PF05426. Alginate_lyase. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALGL_PSEU2

Accession

Primary (citable) accession number: Q4ZXL0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	June 7, 2005
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program