Q4ZQI2 (Q4ZQI2_PSEU2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
6,7-dimethyl-8-ribityllumazine synthase 1 HAMAP MF_00178
Short name=DMRL synthase 1 HAMAP MF_00178
Short name=Lumazine synthase 1 HAMAP MF_00178
EC=2.5.1.9 HAMAP MF_00178

Alternative name(s):
Riboflavin synthase beta chain 1 HAMAP MF_00178

Gene names

Name:	ribH1 HAMAP MF_00178
Ordered Locus Names:	Psyr_3558

Organism

Pseudomonas syringae pv. syringae (strain B728a) [Complete proteome] [HAMAP] EMBL AAY38590.1

Taxonomic identifier

205918 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas syringae

Protein attributes

Sequence length	170 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8-lumazine By similarity. HAMAP MF_00178
Catalytic activity	2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. HAMAP MF_00178
Pathway	Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2. HAMAP MF_00178
Sequence similarities	Belongs to the DMRL synthase family. HAMAP MF_00178

Ontologies

Keywords
Biological process	Riboflavin biosynthesis HAMAP MF_00178
Molecular function	Transferase HAMAP MF_00178 EMBL AAY38590.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	riboflavin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	riboflavin synthase complex Inferred from electronic annotation. Source: InterPro
Molecular function	riboflavin synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4ZQI2 [UniParc]. Last modified June 7, 2005. Version 1. Checksum: E9CB64A019DA91F2	FASTA	170	18,778
	10 20 30 40 50 60 MQPTAIDSKS KSHANERVAF IQACWHKDIV DQSRKGFIAE MANQGYAESD IDIFEVGGAF 70 80 90 100 110 120 EIPLHAKLLA NTGRYAGIVG AALVVDGGIY RHEFVAQSVV SALMQVQLET EVPVFSVVLT 130 140 150 160 170 PHHFHAGEEH QKFFFDHFVH KGEEAAKTCA DTLTKVRSLR RLDAQQKAAC

References

[1]

"Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000." Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A., Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S., Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M., Kyrpides N.C., Ivanova N., Lindow S.E. Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005) [PubMed: 16043691] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000075 Genomic DNA. Translation: AAY38590.1.
RefSeq	YP_236628.1. NC_007005.1.
3D structure databases
ProteinModelPortal	Q4ZQI2.
SMR	Q4ZQI2. Positions 17-146.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4ZQI2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3369089.
GenomeReviews	Gene locus Psyr_3558 in contig CP000075_GR.
KEGG	psb:Psyr_3558.
NMPDR	fig|205918.4.peg.3995.
PATRIC	19987782. VBIPseSyr42314_3644.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0054.
HOGENOM	HBG311126.
OMA	RRYTAIV.
ProtClustDB	PRK12419.
Enzyme and pathway databases
BioCyc	PSYR205918:PSYR_3558-MONOMER.
Family and domain databases
HAMAP	MF_00178. Lumazine_synth. [Tree]
InterPro	IPR002180. DMRL_synthase. [Graphical view]
Gene3D	G3DSA:3.40.50.960. DMRL_synthase. 1 hit.
KO	K00794.
PANTHER	PTHR21058. DMRL_synthase. 1 hit.
Pfam	PF00885. DMRL_synthase. 1 hit. [Graphical view]
SUPFAM	SSF52121. DMRL_synthase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4ZQI2_PSEU2

Accession

Primary (citable) accession number: Q4ZQI2

Entry history

Integrated into UniProtKB/TrEMBL:	June 7, 2005
Last sequence update:	June 7, 2005
Last modified:	December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)