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Q4ZNZ2 (Q4ZNZ2_PSEU2) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047
EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Psyr_4100
OrganismPseudomonas syringae pv. syringae (strain B728a) [Complete proteome] [HAMAP] EMBL AAY39130.1
Taxonomic identifier205918 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas syringae ›

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS005905 HAMAP-Rule MF_00047

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005905 HAMAP-Rule MF_00047

Subcellular location

Cytoplasm By similarity SAAS SAAS005905 HAMAP-Rule MF_00047.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. SAAS SAAS005905 HAMAP-Rule MF_00047

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain117 – 312196ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding143 – 19856ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2661Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2791Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2791Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2811Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
Q4ZNZ2 [UniParc].

Last modified June 7, 2005. Version 1.
Checksum: 84EECFF371B90260

FASTA31933,800
        10         20         30         40         50         60 
MTAVAQSSLR STLEPKSFGR VAVLFGGKSA ERAVSLNSGN AVLGALLEAG VDAFGIDVGD 

        70         80         90        100        110        120 
DFLQRLVSEK IDRAFIVLHG RGGEDGTMQG LLECLEIPYT GSGVLASALA MDKLRTKQVW 

       130        140        150        160        170        180 
QSLGLATPAH AVLENESDCI CAATELGLPL IVKPAHEGSS IGMAKVNSVD ELIAAWKAAS 

       190        200        210        220        230        240 
TYDSQVLVEQ WIQGPEFTVA SLRGQVLPPI GLGTPHSFYD YDAKYLASDT QYRIPCGLGD 

       250        260        270        280        290        300 
AQEQELKQLA ARACDAIGIA GWARTDVMQD AQGKFWLLEV NTVPGMTDHS LVPMAARAAG 

       310 
LDFQQLVLAI LADSVQARG

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References

[1]"Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000."
Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A., Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S., Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M., Kyrpides N.C., Ivanova N., Lindow S.E.
Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B728a.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000075 Genomic DNA. Translation: AAY39130.1.
RefSeqYP_237168.1. NC_007005.1.

3D structure databases

ProteinModelPortalQ4ZNZ2.
SMRQ4ZNZ2. Positions 19-312.
ModBaseSearch...

Protein-protein interaction databases

STRING205918.Psyr_4100.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAY39130; AAY39130; Psyr_4100.
GeneID3369636.
KEGGpsb:Psyr_4100.
PATRIC19988940. VBIPseSyr42314_4218.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMAEVLVEKW.
ProtClustDBPRK01372.

Enzyme and pathway databases

BioCycPSYR205918:GJ94-4161-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ4ZNZ2_PSEU2
AccessionPrimary (citable) accession number: Q4ZNZ2
Entry history
Integrated into UniProtKB/TrEMBL: June 7, 2005
Last sequence update: June 7, 2005
Last modified: May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info