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Reviewed, UniProtKB/Swiss-Prot Q4ZMC3 (PQQC_PSEU2)

Last modified June 16, 2009. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Pyrroloquinoline-quinone synthase
    EC=1.3.3.11
Alternative name(s):
    Coenzyme PQQ synthesis protein C
    Pyrroloquinoline quinone biosynthesis protein C
Gene names
Name: pqqC
Ordered Locus Names: Psyr_4672
OrganismPseudomonas syringae pv. syringae (strain B728a) [Complete proteome] [HAMAP]
Taxonomic identifier205918 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

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Protein attributes

Sequence length251 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity.

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family.

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Ontologies

Keywords
   Biological processPQQ biosynthesis
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

pyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 251251Pyrroloquinoline-quinone synthase HAMAP MF_00654
PRO_1000061676

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Sequences

Sequence LengthMass (Da)Tools
Q4ZMC3-1 [UniParc].

Last modified June 7, 2005. Version 1.
Checksum: E5FCA799BA306006

FASTA25129,117
        10         20         30         40         50         60 
MSEATALSPA EFEQALRAKG AYYHIYHPFH VAMYEGRATR EQIQGWVANR FYYQVNIPLK 

        70         80         90        100        110        120 
DAAILANCPD REIRREWIQR LLDHDGAPGE DGGIEAWLRL GQAVGLDPDQ LRSQELVLPG 

       130        140        150        160        170        180 
VRFAVDAYVN FARRANWQEA ASSSLTELFA PQIHQSRLDS WPQHYPWIDP AGYEYFRTRL 

       190        200        210        220        230        240 
GQARRDVEHG LAITLQHYTT YEGQQRMLEI LQFKLDILWS MLDAMSMAYE LNRPPYHSVT 

       250 
DQRVWHKGIT L

« Hide

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References

[1]"Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000."
Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A., Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S., Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M., Kyrpides N.C., Ivanova N., Lindow S.E.
Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005) [PubMed: 16043691] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000075 Genomic DNA. Translation: AAY39699.1.
RefSeqYP_237737.1.

3D structure databases

SMRQ4ZMC3. Positions 7-246.
ModBaseSearch...

Genome annotation databases

GeneID3370222.
GenomeReviewsGene locus Psyr_4672 in contig CP000075_GR.
KEGGpsb:Psyr_4672.
NMPDRfig|205918.4.peg.3735.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ4ZMC3.
OMAQ4ZMC3. DSWPQHY.

Enzyme and pathway databases

BioCycPSYR205918:PSYR_4672-MON.

Family and domain databases

HAMAPMF_00654.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synth_PqqC.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

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Entry information

Entry namePQQC_PSEU2
AccessionPrimary (citable) accession number: Q4ZMC3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 7, 2005
Last modified: June 16, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents