Reviewed, UniProtKB/Swiss-Prot Q4ZLB5 (UBIC_PSEU2)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	Psyr_5030

Organism

Pseudomonas syringae pv. syringae (strain B728a) [Complete proteome] [HAMAP]

Taxonomic identifier

205918 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas syringae

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000240562
Sites
	Binding site	80	1	Substrate By similarity
	Binding site	118	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4ZLB5-1 [UniParc]. Last modified June 7, 2005. Version 1. Checksum: 7CD624FC58A26C55	FASTA	186	20,882
	10 20 30 40 50 60 MTQQSPAFIG PAWLEREQLI DAPDPVMLDW LFNQDSLTRR LDRLSDGRFS VFPQFEGWQP 70 80 90 100 110 120 LRPDECLALG LPEAGEGWVR EVYLRGNGNN WVFARSVAAR SALQDGGLDM DELGTRSLGE 130 140 150 160 170 180 LLFSDPAFVR GTLEVCHYPE AWLPAADAAR GLWARRSRFD RDALSVLVAE VFLPALCTAI HDKDHV

References

[1]

"Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000." Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A., Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S., Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M., Kyrpides N.C., Ivanova N., Lindow S.E. Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005) [PubMed: 16043691] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000075 Genomic DNA. Translation: AAY40057.1.
RefSeq	YP_238095.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q4ZLB5.
Genome annotation databases
GeneID	3370588.
GenomeReviews	Gene locus Psyr_5030 in contig CP000075_GR.
KEGG	psb:Psyr_5030.
NMPDR	fig|205918.4.peg.230.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4ZLB5.
OMA	PVVFAHS.
Enzyme and pathway databases
BioCyc	PSYR205918:PSYR_5030-MON.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_PSEU2

Accession

Primary (citable) accession number: Q4ZLB5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	June 7, 2005
Last modified:	November 3, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)