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Q4ZG55

- GREB1_HUMAN

UniProt

Q4ZG55 - GREB1_HUMAN

Protein

Protein GREB1

Gene

GREB1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (07 Jun 2005)
      Previous versions | rss
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    Functioni

    May play a role in estrogen-stimulated cell proliferation. Acts as a regulator of hormone-dependent cancer growth in breast and prostate cancers.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein GREB1
    Alternative name(s):
    Gene regulated in breast cancer 1 protein
    Gene namesi
    Name:GREB1
    Synonyms:KIAA0575
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:24885. GREB1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA164747489.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 19491949Protein GREB1PRO_0000320944Add
    BLAST

    Proteomic databases

    MaxQBiQ4ZG55.
    PaxDbiQ4ZG55.
    PRIDEiQ4ZG55.

    PTM databases

    PhosphoSiteiQ4ZG55.

    Expressioni

    Tissue specificityi

    Expressed in proliferating prostatic tissue and prostate cancer.1 Publication

    Inductioni

    Estrogen-responsive; regulated by estrogen receptors. Regulated by androgens. The regulatory region of the gene contains 3 estrogen-responsive elements.5 Publications

    Gene expression databases

    ArrayExpressiQ4ZG55.
    BgeeiQ4ZG55.
    GenevestigatoriQ4ZG55.

    Organism-specific databases

    HPAiHPA024616.
    HPA027843.
    HPA028416.

    Interactioni

    Protein-protein interaction databases

    IntActiQ4ZG55. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4ZG55.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1868 – 188821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi1109 – 1232124Ser-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the GREB1 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG86176.
    HOVERGENiHBG107963.
    OMAiNYTSVET.
    OrthoDBiEOG76X5Z7.
    PhylomeDBiQ4ZG55.
    TreeFamiTF329531.

    Family and domain databases

    InterProiIPR028422. GREB1.
    [Graphical view]
    PANTHERiPTHR15720. PTHR15720. 1 hit.

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q4ZG55-1) [UniParc]FASTAAdd to Basket

    Also known as: GREB1a

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MGNSYAGQLK TTRFEEVLHN SIEASLRSNN LVPRPIFSQL YLEAEQQLAA     50
    LEGGSRVDNE EEEEEGEGGL ETNGPPNPFQ LHPLPEGCCT TDGFCQAGKD 100
    LRLVSISNEP MDVPAGFLLV GVKSPSLPDH LLVCAVDKRF LPDDNGHNAL 150
    LGFSGNCVGC GKKGFCYFTE FSNHINLKLT TQPKKQKHLK YYLVRNAQGT 200
    LTKGPLICWK GSEFRSRQIP ASTCSSSLFP ALESTAAFPS EPVPGTNPSI 250
    LMGAQQAGPA SDHPSLNAAM GPAVFNGKDS PKCQQLAKNN LLALPRPSAL 300
    GILSNSGPPK KRHKGWSPES PSAPDGGCPQ GGGNRAKYES AGMSCVPQVG 350
    LVGPASVTFP VVASGEPVSV PDNLLKICKA KPVIFKGHGN FPYLCGNLND 400
    VVVSPLLYTC YQNSQSVSRA YEQYGASAIQ PISEEMQLLL TVYYLVQLAA 450
    DQVPLMEDLE QIFLRSWRES HLTEIRQYQQ APPQPFPPAP SAAAPVTSAQ 500
    LPWLASLAAS SCNDSVHVIE CAYSLAEGLS EMFRLLVEGK LAKTNYVVII 550
    CACRSAAIDS CIAVTGKYQA RILSESLLTP AEYQKEVNYE LVTGKVDSLG 600
    AFFSTLCPEG DIDILLDKFH QENQGHISSS LAASSVTKAA SLDVSGTPVC 650
    TSYNLEPHSI RPFQLAVAQK LLSHVCSIAD SSTQNLDLGS FEKVDFLICI 700
    PPSEVTYQQT LLHVWHSGVL LELGLKKEHM TKQRVEQYVL KLDTEAQTKF 750
    KAFLQNSFQN PHTLFVLIHD HAHWDLVSST VHNLYSQSDP SVGLVDRLLN 800
    CREVKEAPNI VTLHVTSFPY ALQTQHTLIS PYNEIHWPAS CSNGVDLYHE 850
    NKKYFGLSEF IESTLSGHSL PLLRYDSSFE AMVTALGKRF PRLHSAVIRT 900
    FVLVQHYAAA LMAVSGLPQM KNYTSVETLE ITQNLLNSPK QCPCGHGLMV 950
    LLRVPCSPLA VVAYERLAHV RARLALEEHF EIILGSPSSG VTVGKHFVKQ 1000
    LRMWQKIEDV EWRPQTYLEL EGLPCILIFS GMDPHGESLP RSLRYCDLRL 1050
    INSSCLVRTA LEQELGLAAY FVSNEVPLEK GARNEALESD AEKLSSTDNE 1100
    DEELGTEGST SEKRSPMKRE RSRSHDSASS SLSSKASGSA LGGESSAQPT 1150
    ALPQGEHARS PQPRGPAEEG RAPGEKQRPR ASQGPPSAIS RHSPGPTPQP 1200
    DCSLRTGQRS VQVSVTSSCS QLSSSSGSSS SSVAPAAGTW VLQASQCSLT 1250
    KACRQPPIVF LPKLVYDMVV STDSSGLPKA ASLLPSPSVM WASSFRPLLS 1300
    KTMTSTEQSL YYRQWTVPRP SHMDYGNRAE GRVDGFHPRR LLLSGPPQIG 1350
    KTGAYLQFLS VLSRMLVRLT EVDVYDEEEI NINLREESDW HYLQLSDPWP 1400
    DLELFKKLPF DYIIHDPKYE DASLICSHYQ GIKSEDRGMS RKPEDLYVRR 1450
    QTARMRLSKY AAYNTYHHCE QCHQYMGFHP RYQLYESTLH AFAFSYSMLG 1500
    EEIQLHFIIP KSKEHHFVFS QPGGQLESMR LPLVTDKSHE YIKSPTFTPT 1550
    TGRHEHGLFN LYHAMDGASH LHVLVVKEYE MAIYKKYWPN HIMLVLPSIF 1600
    NSAGVGAAHF LIKELSYHNL ELERNRQEEL GIKPQDIWPF IVISDDSCVM 1650
    WNVVDVNSAG ERSREFSWSE RNVSLKHIMQ HIEAAPDIMH YALLGLRKWS 1700
    SKTRASEVQE PFSRCHVHNF IILNVDLTQN VQYNQNRFLC DDVDFNLRVH 1750
    SAGLLLCRFN RFSVMKKQIV VGGHRSFHIT SKVSDNSAAV VPAQYICAPD 1800
    SKHTFLAAPA QLLLEKFLQH HSHLFFPLSL KNHDHPVLSV DCYLNLGSQI 1850
    SVCYVSSRPH SLNISCSDLL FSGLLLYLCD SFVGASFLKK FHFLKGATLC 1900
    VICQDRSSLR QTVVRLELED EWQFRLRDEF QTANAREDRP LFFLTGRHI 1949
    Length:1,949
    Mass (Da):216,467
    Last modified:June 7, 2005 - v1
    Checksum:iBA12C0535B166BC4
    GO
    Isoform 2 (identifier: Q4ZG55-2) [UniParc]FASTAAdd to Basket

    Also known as: GREB1b

    The sequence of this isoform differs from the canonical sequence as follows:
         450-457: ADQVPLME → HQIRNPDV
         458-1949: Missing.

    Show »
    Length:457
    Mass (Da):48,935
    Checksum:i2C0028B0ECC23CB4
    GO
    Isoform 3 (identifier: Q4ZG55-3) [UniParc]FASTAAdd to Basket

    Also known as: GREB1c

    The sequence of this isoform differs from the canonical sequence as follows:
         387-409: GHGNFPYLCGNLNDVVVSPLLYT → VFVNGATQMVALGPAEPASPRSL
         410-1949: Missing.

    Show »
    Length:409
    Mass (Da):43,253
    Checksum:i0E03659DC466B4C0
    GO
    Isoform 4 (identifier: Q4ZG55-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1002: Missing.

    Show »
    Length:947
    Mass (Da):107,227
    Checksum:i21023519D9B054E9
    GO

    Sequence cautioni

    The sequence BAA25501.2 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti829 – 8291I → S in AAG39036. (PubMed:11103799)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti77 – 771N → T.2 Publications
    Corresponds to variant rs10929757 [ dbSNP | Ensembl ].
    VAR_039313
    Natural varianti122 – 1221V → A.
    Corresponds to variant rs4669751 [ dbSNP | Ensembl ].
    VAR_039314
    Natural varianti346 – 3461V → M.
    Corresponds to variant rs6744817 [ dbSNP | Ensembl ].
    VAR_039315
    Natural varianti359 – 3591F → L.
    Corresponds to variant rs35188552 [ dbSNP | Ensembl ].
    VAR_061654
    Natural varianti632 – 6321A → T.
    Corresponds to variant rs36030386 [ dbSNP | Ensembl ].
    VAR_061655
    Natural varianti973 – 9731R → Q.
    Corresponds to variant rs3762579 [ dbSNP | Ensembl ].
    VAR_039316
    Natural varianti1463 – 14631Y → C.
    Corresponds to variant rs11695925 [ dbSNP | Ensembl ].
    VAR_039317
    Natural varianti1687 – 16871D → N.2 Publications
    Corresponds to variant rs2304402 [ dbSNP | Ensembl ].
    VAR_039318
    Natural varianti1814 – 18141L → V.
    Corresponds to variant rs34955282 [ dbSNP | Ensembl ].
    VAR_039319

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 10021002Missing in isoform 4. 2 PublicationsVSP_031757Add
    BLAST
    Alternative sequencei387 – 40923GHGNF…PLLYT → VFVNGATQMVALGPAEPASP RSL in isoform 3. 1 PublicationVSP_031758Add
    BLAST
    Alternative sequencei410 – 19491540Missing in isoform 3. 1 PublicationVSP_031759Add
    BLAST
    Alternative sequencei450 – 4578ADQVPLME → HQIRNPDV in isoform 2. 1 PublicationVSP_031760
    Alternative sequencei458 – 19491492Missing in isoform 2. 1 PublicationVSP_031761Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF245388 mRNA. Translation: AAG39036.1.
    AF245389 mRNA. Translation: AAG39037.1.
    AF245390 mRNA. Translation: AAG39038.1.
    AB011147 mRNA. Translation: BAA25501.2. Different initiation.
    AC011994 Genomic DNA. Translation: AAX88907.1.
    AC110754 Genomic DNA. No translation available.
    CH471053 Genomic DNA. Translation: EAX00927.1.
    CH471053 Genomic DNA. Translation: EAX00928.1.
    BC054502 mRNA. Translation: AAH54502.1.
    CCDSiCCDS33146.1. [Q4ZG55-2]
    CCDS33147.1. [Q4ZG55-3]
    CCDS42655.1. [Q4ZG55-1]
    PIRiT00340.
    RefSeqiNP_055483.2. NM_014668.3. [Q4ZG55-1]
    NP_149081.1. NM_033090.2. [Q4ZG55-2]
    NP_683701.2. NM_148903.2. [Q4ZG55-3]
    XP_005246249.1. XM_005246192.2. [Q4ZG55-1]
    XP_005246254.1. XM_005246197.1. [Q4ZG55-4]
    XP_006711967.1. XM_006711904.1. [Q4ZG55-1]
    XP_006711968.1. XM_006711905.1. [Q4ZG55-1]
    XP_006711969.1. XM_006711906.1. [Q4ZG55-1]
    UniGeneiHs.467733.

    Genome annotation databases

    EnsembliENST00000234142; ENSP00000234142; ENSG00000196208. [Q4ZG55-1]
    ENST00000263834; ENSP00000263834; ENSG00000196208. [Q4ZG55-3]
    ENST00000381483; ENSP00000370892; ENSG00000196208. [Q4ZG55-2]
    ENST00000381486; ENSP00000370896; ENSG00000196208. [Q4ZG55-1]
    ENST00000396123; ENSP00000379429; ENSG00000196208. [Q4ZG55-4]
    GeneIDi9687.
    KEGGihsa:9687.
    UCSCiuc002rbk.1. human. [Q4ZG55-1]
    uc002rbl.3. human. [Q4ZG55-3]
    uc002rbn.1. human. [Q4ZG55-2]
    uc002rbp.1. human. [Q4ZG55-4]

    Polymorphism databases

    DMDMi74739248.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Web resourcesi

    Atlas of Genetics and Cytogenetics in Oncology and Haematology

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF245388 mRNA. Translation: AAG39036.1 .
    AF245389 mRNA. Translation: AAG39037.1 .
    AF245390 mRNA. Translation: AAG39038.1 .
    AB011147 mRNA. Translation: BAA25501.2 . Different initiation.
    AC011994 Genomic DNA. Translation: AAX88907.1 .
    AC110754 Genomic DNA. No translation available.
    CH471053 Genomic DNA. Translation: EAX00927.1 .
    CH471053 Genomic DNA. Translation: EAX00928.1 .
    BC054502 mRNA. Translation: AAH54502.1 .
    CCDSi CCDS33146.1. [Q4ZG55-2 ]
    CCDS33147.1. [Q4ZG55-3 ]
    CCDS42655.1. [Q4ZG55-1 ]
    PIRi T00340.
    RefSeqi NP_055483.2. NM_014668.3. [Q4ZG55-1 ]
    NP_149081.1. NM_033090.2. [Q4ZG55-2 ]
    NP_683701.2. NM_148903.2. [Q4ZG55-3 ]
    XP_005246249.1. XM_005246192.2. [Q4ZG55-1 ]
    XP_005246254.1. XM_005246197.1. [Q4ZG55-4 ]
    XP_006711967.1. XM_006711904.1. [Q4ZG55-1 ]
    XP_006711968.1. XM_006711905.1. [Q4ZG55-1 ]
    XP_006711969.1. XM_006711906.1. [Q4ZG55-1 ]
    UniGenei Hs.467733.

    3D structure databases

    ProteinModelPortali Q4ZG55.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q4ZG55. 1 interaction.

    PTM databases

    PhosphoSitei Q4ZG55.

    Polymorphism databases

    DMDMi 74739248.

    Proteomic databases

    MaxQBi Q4ZG55.
    PaxDbi Q4ZG55.
    PRIDEi Q4ZG55.

    Protocols and materials databases

    DNASUi 9687.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000234142 ; ENSP00000234142 ; ENSG00000196208 . [Q4ZG55-1 ]
    ENST00000263834 ; ENSP00000263834 ; ENSG00000196208 . [Q4ZG55-3 ]
    ENST00000381483 ; ENSP00000370892 ; ENSG00000196208 . [Q4ZG55-2 ]
    ENST00000381486 ; ENSP00000370896 ; ENSG00000196208 . [Q4ZG55-1 ]
    ENST00000396123 ; ENSP00000379429 ; ENSG00000196208 . [Q4ZG55-4 ]
    GeneIDi 9687.
    KEGGi hsa:9687.
    UCSCi uc002rbk.1. human. [Q4ZG55-1 ]
    uc002rbl.3. human. [Q4ZG55-3 ]
    uc002rbn.1. human. [Q4ZG55-2 ]
    uc002rbp.1. human. [Q4ZG55-4 ]

    Organism-specific databases

    CTDi 9687.
    GeneCardsi GC02P011674.
    HGNCi HGNC:24885. GREB1.
    HPAi HPA024616.
    HPA027843.
    HPA028416.
    MIMi 611736. gene.
    neXtProti NX_Q4ZG55.
    PharmGKBi PA164747489.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG86176.
    HOVERGENi HBG107963.
    OMAi NYTSVET.
    OrthoDBi EOG76X5Z7.
    PhylomeDBi Q4ZG55.
    TreeFami TF329531.

    Miscellaneous databases

    GenomeRNAii 9687.
    NextBioi 36380.
    PROi Q4ZG55.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q4ZG55.
    Bgeei Q4ZG55.
    Genevestigatori Q4ZG55.

    Family and domain databases

    InterProi IPR028422. GREB1.
    [Graphical view ]
    PANTHERi PTHR15720. PTHR15720. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer."
      Ghosh M.G., Thompson D.A., Weigel R.J.
      Cancer Res. 60:6367-6375(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3), NUCLEOTIDE SEQUENCE [MRNA] OF 1-1001 (ISOFORM 1).
      Tissue: Mammary carcinoma.
    2. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Nagase T., Ishikawa K., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
      DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
      Tissue: Brain.
    3. Ohara O., Nagase T., Ishikawa K.
      Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: SEQUENCE REVISION.
    4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS THR-77 AND ASN-1687.
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), VARIANTS THR-77 AND ASN-1687.
      Tissue: Skin.
    7. Cited for: INDUCTION BY ESTROGEN.
    8. "GREB 1 is a critical regulator of hormone dependent breast cancer growth."
      Rae J.M., Johnson M.D., Scheys J.O., Cordero K.E., Larios J.M., Lippman M.E.
      Breast Cancer Res. Treat. 92:141-149(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: POSSIBLE FUNCTION, INDUCTION BY ESTROGEN.
    9. "GREB1 is a novel androgen-regulated gene required for prostate cancer growth."
      Rae J.M., Johnson M.D., Cordero K.E., Scheys J.O., Larios J.M., Gottardis M.M., Pienta K.J., Lippman M.E.
      Prostate 66:886-894(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY, INDUCTION.
    10. "Regulation of GREB1 transcription by estrogen receptor alpha through a multipartite enhancer spread over 20 kb of upstream flanking sequences."
      Deschenes J., Bourdeau V., White J.H., Mader S.
      J. Biol. Chem. 282:17335-17339(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION BY ESTROGEN.
    11. "Long-range activation of GREB1 by estrogen receptor via three distal consensus estrogen-responsive elements in breast cancer cells."
      Sun J., Nawaz Z., Slingerland J.M.
      Mol. Endocrinol. 21:2651-2662(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION BY ESTROGEN.

    Entry informationi

    Entry nameiGREB1_HUMAN
    AccessioniPrimary (citable) accession number: Q4ZG55
    Secondary accession number(s): A6NHD0
    , A6NKN0, B5MDA9, O60321, Q7Z5S2, Q9H2Q6, Q9H2Q7, Q9H2Q8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: June 7, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3