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Protein

DNA ligase

Gene

PB000674.02.0

Organism
Plasmodium berghei (strain Anka)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PB000674.02.0Imported
OrganismiPlasmodium berghei (strain Anka)Imported
Taxonomic identifieri5823 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Vinckeia)
ProteomesiUP000007720 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiPlasmoDB:PBANKA_140260.

Interactioni

Protein-protein interaction databases

STRINGi5821.PBANKA_140260.

Structurei

3D structure databases

ProteinModelPortaliQ4YVG1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036006.
InParanoidiQ4YVG1.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 2 hits.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4YVG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLLLILLT KMFFCKIKRY MRTEYNYVTP FMKSKLFHNY KNKFNVIILK
60 70 80 90 100
NIRNNVPNRN DKYLKCLSFP KKLDGGEQCD TKIEETHVKN EEKEASKRKN
110 120 130 140 150
TNDDSAKTKK SKVKNENEIK KGSLFNCKVY EDEKISDLTS PKFNPANFDI
160 170 180 190 200
SNLCLSEKDK IKHKFKDSLL FTFLTNTFNQ IEELKGSGAG SKKNVAIILS
210 220 230 240 250
NVFRVLIYYS PNDLIPAVYI TLNKVAPDYQ NVEAGVGEAL ILKTMSEAYS
260 270 280 290 300
RTETSIKKDL QQIEDLGIIA ESCSCKMRTI FPLPLTIQSV FNELKSIPNI
310 320 330 340 350
SGSNSQQKKR EVIKKLLVSA KTSEAKYIVR FLQQRLRIGV NSATVLQALA
360 370 380 390 400
YAFVLTRPEI PENIIKDGKM MNEKLLNEQT MVKGDKDNCN DGTTEVKNEN
410 420 430 440 450
DIKLEKQNDT DNKTNMLDID QFNNLVKSIK IRNERMSKPN LFFNIGKEGD
460 470 480 490 500
TRLLPIFKEL KNAYCDINND SDIFECMEKS VKSALCELPN IEMIIQNLLS
510 520 530 540 550
GDDMNVLMKK CTVKTGVPVQ PMLAKPTKGI QEVLDRFNNV TFTCEYKYDG
560 570 580 590 600
ERAQIHYIDK DNIKIFSRNL ETMTEKYPDV IQIVKDQIMP GVTESIIDSE
610 620 630 640 650
VVAYDIENKK ILPFQILTTR KRKDVDIENI KVKICLFPFD LICCNGIPVI
660 670 680 690 700
KEPLEIRRKL LYSLLKCKEG VLEYATHSEM NNIDDIDIFL QDAIENNCEG
710 720 730 740 750
LMVKTLLDNA SYEPSRRSLN WLKVKKDYIE GLSDSVDLVP IAGYYGKGKR
760 770 780 790 800
SGVYGAFVLA AYNSETENFQ TVCKAGTGFS DEILNALHES LSDKIIPNKK
810 820 830 840 850
SYYEVSDKLN PDVWFDAHYV WEIKAADLSL SPVHTAAIGV YSDDKGIGLR
860 870 880 890
FPRFLRLRDD KNPEQATTAQ QIVEFYEAQF ASKKNKNNNY NDESGSE
Length:897
Mass (Da):102,547
Last modified:July 5, 2005 - v1
Checksum:i7B6045DEAC2307B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAAI01002272 Genomic DNA. Translation: CAH97995.1.
RefSeqiXP_677122.1. XM_672030.1.

Genome annotation databases

GeneIDi3425646.
KEGGipbe:PB000674.02.0.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAAI01002272 Genomic DNA. Translation: CAH97995.1.
RefSeqiXP_677122.1. XM_672030.1.

3D structure databases

ProteinModelPortaliQ4YVG1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5821.PBANKA_140260.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3425646.
KEGGipbe:PB000674.02.0.

Organism-specific databases

EuPathDBiPlasmoDB:PBANKA_140260.

Phylogenomic databases

HOGENOMiHOG000036006.
InParanoidiQ4YVG1.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 2 hits.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ANKAImported.

Entry informationi

Entry nameiQ4YVG1_PLABA
AccessioniPrimary (citable) accession number: Q4YVG1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: June 24, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.