Q4XN87 (Q4XN87_PLACH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uracil-DNA glycosylase, putative EMBL CAH81625.1

Gene names

ORF Names:

PC000728.04.0 EMBL CAH81625.1

Organism

Plasmodium chabaudi [Reference proteome]

Taxonomic identifier

5825 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Vinckeia)

Protein attributes

Sequence length	324 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine By similarity. RuleBase RU003780
Catalytic activity	Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil. RuleBase RU003780
Sequence similarities	Belongs to the uracil-DNA glycosylase family. RuleBase RU003780

Ontologies

Keywords
Biological process	DNA damage DNA repair RuleBase RU003780
Molecular function	Glycosidase RuleBase RU003780 Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	base-excision repair Inferred from electronic annotation. Source: InterPro
Molecular_function	uracil DNA N-glycosylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4XN87 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 2C05786C7B29E0CE	FASTA	324	37,514
	10 20 30 40 50 60 MNKLKVQKTI DQFFAIKPKK SVSANIEVMT SASSDSLVSS CIEEIEKTQN NLKKRKINND 70 80 90 100 110 120 NDIIKKELRL SKDEEIIDIS NVGIEPGMIN KKIMQKELAD YNYIEEIKSL MHTEWYEHLE 130 140 150 160 170 180 GELKKNYFKN MYLRIKDERK KKVIYPPENL VFTAFLKTPL SKIKVVIVGQ DPYHQKGQAM 190 200 210 220 230 240 GLCFSVPVGI KIPPSLKNIL KEIKQKSDHG DLTSWTEQGV FLLNTSLTVE ENKPASHKNY 250 260 270 280 290 300 GWETFTDKVI DIINEKKKQI VFMLWGNFAI KKCAKIDTKK HFILKSGHPS PLSIKHFVNC 310 320 DHFNKCNNFL IKNNMSPIKW ELPQ

References

[1]

"A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses." Hall N., Karras M., Raine J.D., Carlton J.M., Kooij T.W.A., Berriman M., Florens L., Janssen C.S., Pain A., Christophides G.K., James K., Rutherford K., Harris B., Harris D., Churcher C.M., Quail M.A., Ormond D., Doggett J. , Trueman H.E., Mendoza J., Bidwell S.L., Rajandream M.A., Carucci D.J., Yates J.R. III, Kafatos F.C., Janse C.J., Barrell B.G., Turner C.M.R., Waters A.P., Sinden R.S. Science 307:82-86(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CAAJ01004478 Genomic DNA. Translation: CAH81625.1.
RefSeq	XP_742629.1. XM_737536.1.
3D structure databases
ProteinModelPortal	Q4XN87.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	PCHAS_102850:mRNA; PCHAS_102850:pep; PCHAS_102850.
GeneID	3495721.
KEGG	pcb:PC000728.04.0.
Organism-specific databases
EuPathDB	PlasmoDB:PCHAS_102850.
Phylogenomic databases
HOGENOM	HOG000229528.
KO	K03648.
Family and domain databases
Gene3D	3.40.470.10. 1 hit.
HAMAP	MF_00148. UDG.
InterPro	IPR018085. Ura-DNA_Glyclase_AS. IPR002043. Ura_DNA_glycsylse. IPR005122. Uracil-DNA_glycosylase-like. [Graphical view]
PANTHER	PTHR11264. PTHR11264. 1 hit.
Pfam	PF03167. UDG. 1 hit. [Graphical view]
SMART	SM00986. UDG. 1 hit. [Graphical view]
SUPFAM	SSF52141. UDNA_glycsylseSF. 1 hit.
TIGRFAMs	TIGR00628. ung. 1 hit.
PROSITE	PS00130. U_DNA_GLYCOSYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4XN87_PLACH

Accession

Primary (citable) accession number: Q4XN87

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	March 6, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)