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Reviewed, UniProtKB/Swiss-Prot Q4X1Q4 (ADA_ASPFU)

Last modified November 3, 2009. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase
Gene names
Name: aah1
ORF Names: AFUA_2G09150
OrganismAspergillus fumigatus (Sartorya fumigata) [Complete proteome]
Taxonomic identifier5085 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesTrichocomaceaemitosporic TrichocomaceaeAspergillus

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence similarities

Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Cellular componentCytoplasm
Nucleus
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine ribonucleoside monophosphate biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionadenosine deaminase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 354354Adenosine deaminase
PRO_0000256230

Sites

Active site2111 Potential
Active site2581 Potential
Active site2911 Potential
Active site2921 Potential

Sequences

Sequence LengthMass (Da)Tools
Q4X1Q4-1 [UniParc].

Last modified July 5, 2005. Version 1.
Checksum: 591204D6B19AB461

FASTA35439,864
        10         20         30         40         50         60 
MCQSPLHDFL HGLPKCEHHV HLEGCVTPEL IFQLAEKNNI QLPNPATHPA YASVEALRAR 

        70         80         90        100        110        120 
YAEFTSLNDF LDFYFHGMSV LHHQSDFEEL AWAYFQKAHA DGVHHAEVFF DPQVHQARGI 

       130        140        150        160        170        180 
DYETVVSGFT AGCKRAEREL GLSTRLILCF VRHLPVDSAT KLYELALASN HFESRVVHGL 

       190        200        210        220        230        240 
GWSSSEVGPP KDMFREIYAS ASGKGIRLTA HAGEEGDPTY ISTALELGAR RIDHGIRLVE 

       250        260        270        280        290        300 
DPELMERVAR EGIMLTVCPL SNVRLRCVQS VEQVPIRKFL DAGVKFSINS DDPAYFGGYI 

       310        320        330        340        350 
LDNYCAVQEA FQLSILEWRV IAENSVNESW IDEARKAELL KRIDDHVQKH TVVA 

« Hide

References

Cross-references

Sequence databases

AAHF01000001 Genomic DNA. Translation: EAL93211.1.
RefSeqXP_755249.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ4X1Q4.

Genome annotation databases

GeneID3513729.
GenomeReviewsGene locus aah1 in contig CM000170_GR.
KEGGafm:AFUA_2G09150.

Phylogenomic databases

HOGENOMQ4X1Q4.
OMACLLRHLP.

Enzyme and pathway databases

BRENDA3.5.4.4. 18841.

Family and domain databases

InterProIPR006650. A/AMP_deam_AS.
IPR001365. A/AMP_deaminase.
IPR006330. A_deaminase.
[Graphical view]
PANTHERPTHR11409. A/AMP_deaminase. 1 hit.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. aden_deam. 1 hit.
PROSITEPS00485. A_DEAMINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADA_ASPFU
AccessionPrimary (citable) accession number: Q4X1Q4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 5, 2005
Last modified: November 3, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents