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Protein

Probable glucan endo-1,6-beta-glucosidase B

Gene

exgB

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides (By similarity).By similarity

Catalytic activityi

Random hydrolysis of (1->6)-linkages in (1->6)-beta-D-glucans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei219Proton donorBy similarity1
Active sitei320NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucan endo-1,6-beta-glucosidase B (EC:3.2.1.75)
Alternative name(s):
Beta-1,6-glucanase B
Endo-1,6-beta-D-glucanase B
Endo-1,6-beta-glucanase B
Gene namesi
Name:exgB
ORF Names:AFUA_2G09350
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:Afu2g09350

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000039470718 – 396Probable glucan endo-1,6-beta-glucosidase BAdd BLAST379

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi30N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi272N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi5085.CADAFUBP00002464

Structurei

3D structure databases

ProteinModelPortaliQ4X1N4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000217590
InParanoidiQ4X1N4
KOiK22277
OMAiDSEHFPQ
OrthoDBiEOG092C2511

Family and domain databases

InterProiView protein in InterPro
IPR001547 Glyco_hydro_5
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00150 Cellulase, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q4X1N4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRRLAAFSA LSGLATAWLP EVNKKITSTN GTNLFTSSNG KIRGVNLGSQ
60 70 80 90 100
FVFEPWIAEK AWSDMGCGGQ KSEFDCVSRL GQANANSAFA SHWGSWITQD
110 120 130 140 150
DIAEMVSYGL NTIRVPVGYW MREDLVYSDS EHFPQGGLQY LENLCEWASD
160 170 180 190 200
AGLYIIIDLH GAPGAQTPQN PFTGQYAPIA GFYQDYQFEG ALKFLEWMTT
210 220 230 240 250
NIHQNDKFRN VGMLEVVNEP VQDAGKVGSM RSSYYPNAFK RIRAAEQSLN
260 270 280 290 300
IDRNNYLHIQ MMDRLWGSGD PNESLTDTYY AAYDDHRYLK WASVAVSKDS
310 320 330 340 350
YISTSCSDQL NSNTPTIVGE WSLSVPDNVQ WNSDWSPDSN KDFYKKWFAA
360 370 380 390
QVTAYERQQG WIFWTWKAQL GDYRWSYQGG LLLTRPGIGD QQVLTL
Length:396
Mass (Da):44,795
Last modified:July 5, 2005 - v1
Checksum:iD53B00929BC0E598
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000001 Genomic DNA Translation: EAL93231.1
RefSeqiXP_755269.1, XM_750176.1

Genome annotation databases

EnsemblFungiiCADAFUAT00004063; CADAFUAP00004063; CADAFUAG00004063
GeneIDi3513261
KEGGiafm:AFUA_2G09350

Similar proteinsi

Entry informationi

Entry nameiEXGB_ASPFU
AccessioniPrimary (citable) accession number: Q4X1N4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: July 5, 2005
Last modified: April 25, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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