Reviewed,
UniProtKB/Swiss-Prot Q4WYS7 (NNT1_ASPFU)
Last modified
February 9, 2010.
Version 30.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Putative nicotinamide N-methyltransferase EC=2.1.1.1 | ||||
| Gene names |
| ||||
| Organism | Aspergillus fumigatus (Sartorya fumigata) [Complete proteome] | ||||
| Taxonomic identifier | 5085 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus |
Protein attributes
| Sequence length | 259 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Putative nicotinamide N-methyltransferase involved in rDNA silencing and in lifespan determination By similarity. |
| Catalytic activity | S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-methylnicotinamide. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the NNT1 family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | S-adenosyl-L-methionine |
| Molecular function | Methyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | nicotinamide N-methyltransferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 259 | 259 | Putative nicotinamide N-methyltransferase | PRO_0000096890 | |||
Sequences
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References
| [1] | "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus." Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L. Denning D.W.Nature 438:1151-1156(2005) [PubMed: 16372009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Af293 / CBS 101355 / FGSC A1100. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AAHF01000002 Genomic DNA. Translation: EAL92176.1. |
| RefSeq | XP_754214.1. |
3D structure databases | |
| SMR | Q4WYS7. Positions 38-254. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q4WYS7. |
Genome annotation databases | |
| GeneID | 3512117. |
| KEGG | afm:AFUA_3G14110. |
Phylogenomic databases | |
| eggNOG | fuNOG05731. |
| HOGENOM | HBG397955. |
| OMA | VVFSPHR. |
| OrthoDB | EOG92BZS7. |
| PhylomeDB | Q4WYS7. |
Enzyme and pathway databases | |
| BRENDA | 2.1.1.1. 18841. |
Family and domain databases | |
| InterPro | IPR019410. Methyltransferase-16_put. [Graphical view] |
| Pfam | PF10294. Methyltransf_16. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | NNT1_ASPFU | ||||||||
| Accession | Primary (citable) accession number: Q4WYS7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||

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